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The map label for this gene is argB [H]

Identifier: 123968091

GI number: 123968091

Start: 485187

End: 486038

Strand: Reverse

Name: argB [H]

Synonym: A9601_05561

Alternate gene names: 123968091

Gene position: 486038-485187 (Counterclockwise)

Preceding gene: 123968092

Following gene: 123968090

Centisome position: 29.11

GC content: 33.22

Gene sequence:

>852_bases
ATGAATGATTCTCAAAGAGTATCAATATTAAGCGAAGCACTTCCATATATACAAAGTTTCTCAGGTAGAAAAATTGTTAT
CAAGTATGGTGGTTCTGTTATGGAGAATGATAATTTAAAAAATGCTTTTTTTAGAGACATTGCACTTTTATCAACCGTTG
GTGTTTGTCCGATAGTAATTCATGGAGGTGGACCAGAGATTAATAATTGGTTAAGGAAATTAGAAATATCTCCTAAATTC
GAAAATGGATTAAGAATTACTGATCAAAAAACAATGGAAATTGTCGAGATGGTCCTAATGGGAAGAGTTAACAAAGAGAT
TGTAAAAGGGATTAATAAAACTGGATCCTTAGCTGTGGGAATATCAGGTCTTGATGGCAACTTAATTCAATCTAGAGAAC
TAGGAGATGGTAGCCATGGGTTAGTAGGAGAGGTTACAAAAATCAATCCTGAAATATTAGATCCTCTTATTTCTAAAGGA
TACATCCCAATTATTTCTAGCATTGGATCAACTTTGGAGGGTATTTCCCATAACATTAATGCAGATTTTGTTGCTGGAGA
AATTGCTGCTGCAATAAATGCAGAAAAACTTATTCTTCTTACTGATACTCAAGGAATTTTAAAAGAAAAAGATGACAAAA
ATAGTCTTGTTGCAAAAACTAATCTCAAAGAGGCAAGAGATTTTATTGATAAAAAAATTGTGACTGCAGGTATGATTCCA
AAGACAGAATGCTGTATAAGAGCTTTAGCCCAAGGAGTCAAAGCAGCTCACATAATTGATGGACAAATAGAACATTCATT
ACTTCTTGAGATTTTTACAAATTCCGGAATAGGTACAATGATAGTCGCCTAA

Upstream 100 bases:

>100_bases
TAATAAAAAAGAATTTGATTTTATTCTCTTTTATTGAATATAGGGATATATTTGTAAAAACCTAATTTCTCAATTCAATC
AAGTTTTATAAATTTTAATA

Downstream 100 bases:

>100_bases
CCCATGAAAACTTATGAGCAAGTTTTAGAAAAAGTAGAACTTGCTTTAGCTAAAGGTGAGTATCATCATTGCATTGAATT
TCTTTTGCCCATAATCGAAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMENDNLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLRKLEISPKF
ENGLRITDQKTMEIVEMVLMGRVNKEIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKG
YIPIISSIGSTLEGISHNINADFVAGEIAAAINAEKLILLTDTQGILKEKDDKNSLVAKTNLKEARDFIDKKIVTAGMIP
KTECCIRALAQGVKAAHIIDGQIEHSLLLEIFTNSGIGTMIVA

Sequences:

>Translated_283_residues
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMENDNLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLRKLEISPKF
ENGLRITDQKTMEIVEMVLMGRVNKEIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKG
YIPIISSIGSTLEGISHNINADFVAGEIAAAINAEKLILLTDTQGILKEKDDKNSLVAKTNLKEARDFIDKKIVTAGMIP
KTECCIRALAQGVKAAHIIDGQIEHSLLLEIFTNSGIGTMIVA
>Mature_283_residues
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMENDNLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLRKLEISPKF
ENGLRITDQKTMEIVEMVLMGRVNKEIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKG
YIPIISSIGSTLEGISHNINADFVAGEIAAAINAEKLILLTDTQGILKEKDDKNSLVAKTNLKEARDFIDKKIVTAGMIP
KTECCIRALAQGVKAAHIIDGQIEHSLLLEIFTNSGIGTMIVA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=283, Percent_Identity=26.8551236749117, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693208, Length=225, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320913, Length=281, Percent_Identity=31.3167259786477, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 30486; Mature: 30486

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMENDNLKNAFFRDIALLSTVGVCPIVI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHHHHHHHHHHCCCCEEEE
HGGGPEINNWLRKLEISPKFENGLRITDQKTMEIVEMVLMGRVNKEIVKGINKTGSLAVG
ECCCCCHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEE
ISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKGYIPIISSIGSTLEGISHNIN
EECCCCCEEECCCCCCCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
ADFVAGEIAAAINAEKLILLTDTQGILKEKDDKNSLVAKTNLKEARDFIDKKIVTAGMIP
CHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCC
KTECCIRALAQGVKAAHIIDGQIEHSLLLEIFTNSGIGTMIVA
CHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMENDNLKNAFFRDIALLSTVGVCPIVI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHHHHHHHHHHCCCCEEEE
HGGGPEINNWLRKLEISPKFENGLRITDQKTMEIVEMVLMGRVNKEIVKGINKTGSLAVG
ECCCCCHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEE
ISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKGYIPIISSIGSTLEGISHNIN
EECCCCCEEECCCCCCCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
ADFVAGEIAAAINAEKLILLTDTQGILKEKDDKNSLVAKTNLKEARDFIDKKIVTAGMIP
CHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCC
KTECCIRALAQGVKAAHIIDGQIEHSLLLEIFTNSGIGTMIVA
CHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA