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The map label for this gene is cry2 [H]

Identifier: 123967930

GI number: 123967930

Start: 349600

End: 351096

Strand: Reverse

Name: cry2 [H]

Synonym: A9601_03931

Alternate gene names: 123967930

Gene position: 351096-349600 (Counterclockwise)

Preceding gene: 123967933

Following gene: 123967929

Centisome position: 21.03

GC content: 28.32

Gene sequence:

>1497_bases
ATGAAAGAAATAAATATCTTATGGTTTAAGAAAGATTTAAGAATTTTTGATAACGAAGCTCTCTGTGAGGCTATAAAAGA
TAATGATATTTTACCTATTTATATTATTGAGTTAGATATTTGGAGCCAAAATACTCATTCAGATAGACAATGGCAATTTT
GCAAAGAAAGTTTAATAGATTTAAGAAATGCACTTGCTGAGATTGGACAACCATTAATTATTAGGACTGGTAATGTTATT
AATATATTTGATGCAATTAGTTCAAAATTTAAAATCAAAGGTATATATAGCCATCAAGAAACCGGAGATTGGCTTACTTA
TAAAAGAGATCAAAAAGTAAAAGAATGGGCTTTCAGCAAAAATATTATTTGGAAGGAATTTCTACAATTTTCAGTTTTCA
GAGGAAATTTAGATAGGAATAATTGGTCTAAAAAGTGGCAAAAAAATTCCGAAAAAAACTTACTTAAAGCTCCATTAAGA
ATTAATTCTATTAACTTTAATACTGGAGAAATACCCTCAGACGAAATTTTTTCCTTTAAAAAAGAAACTTGTCCAGGAAG
AATGCAAGGTGGAAGAAAGAAAGGTTTAGAGAGAATGCAATACTTCTTTAGTAATAAATTAGATTCTTATTCAAAAGATA
TATCTAGCCCAGAAAAATCATTTGATAGTTGTACAAGACTATCCCCATATATTTGTTGGGGATGCATTTCATTAAAAGAA
ATTTTTCAAAAGGCAAATATATCAAAAAACAATAATTCTAGGATGTTAAAAAGCAGATTAACTTGGCATTGTCATTTTAT
TCAGAAACTTGAAAGTGAACCAGAACTAGAGTTTAGGGAATACCATCCTTTTTTTAAAAATATTAGAGAAAAAAATAATG
AATTACTTTATTCATGGAGTTCAGGTAATACGGGCTTTCCTTTTATAGATGCATGTATGCGCTCATTAAATTTCCATGGA
TGGATTAACTTCAGGATGCGGGCTATGTTAATGTCTTTTGCTAGCTATAATTTATGGCTACCGTGGCAAGACTCAGGTTC
TGAATTAGCAAATAAATTTGTAGATTATGAGCCTGGAATACATTGGAACCAATGCCAAATGCAATCTGGAACTACATCTA
TAAATACCAATAGAATTTATAATCCTATTAAGCAGGGAAAAGATCATGATCCACAAGGAAAATTTATAAAAAAATGGTTA
CCAGAATTAAAGGATTTATCACTTAATTTCATTCATGAACCATGGTTATTATCTAGATTTAATAAAGAAGAATATGAACA
AATTAATTACATAAGACCAATAATTGATATCCCAAATAGCACTAAAAATGCAAAGAAGAAAATTCAGGAAATAACTAAAA
AGGATGGATATTGGGATATCTCAAAAGAAATTTATTTAAAACATGGCTCCAGAAAAAGGCTTAGAAAAAATATAAATAAT
AAAAAAATTATTTCTAGGGAAAAGGAAATACAATACGAATTGAAATTAGATTTCTAA

Upstream 100 bases:

>100_bases
TTGTTATTTTCATTTTTTTGATTTTTAGTTATTCTAAAATTTTTTTATATTTTTCACCTACAAACTTAATCATATTTTTC
TAGTATTAAAAGAAAAAATT

Downstream 100 bases:

>100_bases
ACTTTATTTTAAGAAATTTATAGATTCCTTTTAATGTATAGGAAAGTTTTGTAAATTTTGAAATTCAATATATAAATCCA
CGATGAAGTAATGCAAGCTT

Product: putative deoxyribodipyrimidine photolyase

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MKEINILWFKKDLRIFDNEALCEAIKDNDILPIYIIELDIWSQNTHSDRQWQFCKESLIDLRNALAEIGQPLIIRTGNVI
NIFDAISSKFKIKGIYSHQETGDWLTYKRDQKVKEWAFSKNIIWKEFLQFSVFRGNLDRNNWSKKWQKNSEKNLLKAPLR
INSINFNTGEIPSDEIFSFKKETCPGRMQGGRKKGLERMQYFFSNKLDSYSKDISSPEKSFDSCTRLSPYICWGCISLKE
IFQKANISKNNNSRMLKSRLTWHCHFIQKLESEPELEFREYHPFFKNIREKNNELLYSWSSGNTGFPFIDACMRSLNFHG
WINFRMRAMLMSFASYNLWLPWQDSGSELANKFVDYEPGIHWNQCQMQSGTTSINTNRIYNPIKQGKDHDPQGKFIKKWL
PELKDLSLNFIHEPWLLSRFNKEEYEQINYIRPIIDIPNSTKNAKKKIQEITKKDGYWDISKEIYLKHGSRKRLRKNINN
KKIISREKEIQYELKLDF

Sequences:

>Translated_498_residues
MKEINILWFKKDLRIFDNEALCEAIKDNDILPIYIIELDIWSQNTHSDRQWQFCKESLIDLRNALAEIGQPLIIRTGNVI
NIFDAISSKFKIKGIYSHQETGDWLTYKRDQKVKEWAFSKNIIWKEFLQFSVFRGNLDRNNWSKKWQKNSEKNLLKAPLR
INSINFNTGEIPSDEIFSFKKETCPGRMQGGRKKGLERMQYFFSNKLDSYSKDISSPEKSFDSCTRLSPYICWGCISLKE
IFQKANISKNNNSRMLKSRLTWHCHFIQKLESEPELEFREYHPFFKNIREKNNELLYSWSSGNTGFPFIDACMRSLNFHG
WINFRMRAMLMSFASYNLWLPWQDSGSELANKFVDYEPGIHWNQCQMQSGTTSINTNRIYNPIKQGKDHDPQGKFIKKWL
PELKDLSLNFIHEPWLLSRFNKEEYEQINYIRPIIDIPNSTKNAKKKIQEITKKDGYWDISKEIYLKHGSRKRLRKNINN
KKIISREKEIQYELKLDF
>Mature_498_residues
MKEINILWFKKDLRIFDNEALCEAIKDNDILPIYIIELDIWSQNTHSDRQWQFCKESLIDLRNALAEIGQPLIIRTGNVI
NIFDAISSKFKIKGIYSHQETGDWLTYKRDQKVKEWAFSKNIIWKEFLQFSVFRGNLDRNNWSKKWQKNSEKNLLKAPLR
INSINFNTGEIPSDEIFSFKKETCPGRMQGGRKKGLERMQYFFSNKLDSYSKDISSPEKSFDSCTRLSPYICWGCISLKE
IFQKANISKNNNSRMLKSRLTWHCHFIQKLESEPELEFREYHPFFKNIREKNNELLYSWSSGNTGFPFIDACMRSLNFHG
WINFRMRAMLMSFASYNLWLPWQDSGSELANKFVDYEPGIHWNQCQMQSGTTSINTNRIYNPIKQGKDHDPQGKFIKKWL
PELKDLSLNFIHEPWLLSRFNKEEYEQINYIRPIIDIPNSTKNAKKKIQEITKKDGYWDISKEIYLKHGSRKRLRKNINN
KKIISREKEIQYELKLDF

Specific function: Has no photolyase activity [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI188536100, Length=491, Percent_Identity=22.1995926680244, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI4758072, Length=497, Percent_Identity=24.3460764587525, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI188536103, Length=307, Percent_Identity=25.7328990228013, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1786926, Length=472, Percent_Identity=24.5762711864407, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324962, Length=502, Percent_Identity=23.5059760956175, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17137248, Length=462, Percent_Identity=24.025974025974, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24585455, Length=462, Percent_Identity=24.025974025974, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24648152, Length=503, Percent_Identity=22.0675944333996, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 59375; Mature: 59375

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEINILWFKKDLRIFDNEALCEAIKDNDILPIYIIELDIWSQNTHSDRQWQFCKESLID
CCCEEEEEEECCCHHCCCHHHHHHHCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHH
LRNALAEIGQPLIIRTGNVINIFDAISSKFKIKGIYSHQETGDWLTYKRDQKVKEWAFSK
HHHHHHHCCCCEEEECCCEEEHHHHHCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHC
NIIWKEFLQFSVFRGNLDRNNWSKKWQKNSEKNLLKAPLRINSINFNTGEIPSDEIFSFK
CHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCCHHHHHHH
KETCPGRMQGGRKKGLERMQYFFSNKLDSYSKDISSPEKSFDSCTRLSPYICWGCISLKE
HHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
IFQKANISKNNNSRMLKSRLTWHCHFIQKLESEPELEFREYHPFFKNIREKNNELLYSWS
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHCCCCEEEEEC
SGNTGFPFIDACMRSLNFHGWINFRMRAMLMSFASYNLWLPWQDSGSELANKFVDYEPGI
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCCC
HWNQCQMQSGTTSINTNRIYNPIKQGKDHDPQGKFIKKWLPELKDLSLNFIHEPWLLSRF
CCCCEECCCCCCCCCCHHHHCHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHC
NKEEYEQINYIRPIIDIPNSTKNAKKKIQEITKKDGYWDISKEIYLKHGSRKRLRKNINN
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCHHEEEECCCHHHHHHCCCC
KKIISREKEIQYELKLDF
CHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MKEINILWFKKDLRIFDNEALCEAIKDNDILPIYIIELDIWSQNTHSDRQWQFCKESLID
CCCEEEEEEECCCHHCCCHHHHHHHCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHH
LRNALAEIGQPLIIRTGNVINIFDAISSKFKIKGIYSHQETGDWLTYKRDQKVKEWAFSK
HHHHHHHCCCCEEEECCCEEEHHHHHCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHC
NIIWKEFLQFSVFRGNLDRNNWSKKWQKNSEKNLLKAPLRINSINFNTGEIPSDEIFSFK
CHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCCHHHHHHH
KETCPGRMQGGRKKGLERMQYFFSNKLDSYSKDISSPEKSFDSCTRLSPYICWGCISLKE
HHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
IFQKANISKNNNSRMLKSRLTWHCHFIQKLESEPELEFREYHPFFKNIREKNNELLYSWS
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHCCCCEEEEEC
SGNTGFPFIDACMRSLNFHGWINFRMRAMLMSFASYNLWLPWQDSGSELANKFVDYEPGI
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCCC
HWNQCQMQSGTTSINTNRIYNPIKQGKDHDPQGKFIKKWLPELKDLSLNFIHEPWLLSRF
CCCCEECCCCCCCCCCHHHHCHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHC
NKEEYEQINYIRPIIDIPNSTKNAKKKIQEITKKDGYWDISKEIYLKHGSRKRLRKNINN
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCHHEEEECCCHHHHHHCCCC
KKIISREKEIQYELKLDF
CHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]