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The map label for this gene is sdh [H]

Identifier: 121610297

GI number: 121610297

Start: 3733821

End: 3735227

Strand: Direct

Name: sdh [H]

Synonym: Veis_3361

Alternate gene names: 121610297

Gene position: 3733821-3735227 (Clockwise)

Preceding gene: 121610296

Following gene: 121610298

Centisome position: 67.07

GC content: 66.03

Gene sequence:

>1407_bases
GTGGTACGCGACTTCGCAGGCGTGCTCGTGCGCCGCGGCGCCGGCACCATCGTTGTGCTCGGCTCGGTCGCCGCGCAGGA
TGCTGCGCCACTGATGGCCGCCTATGCTGCCAGCAGGGCCTGTGTGCAGCAGTTGGTGCACTGCGTGCGTTCCGACCTGC
ACGGCTCGGTCGTACGCGTCACCTGTGTGCAACCCGGTACCACCCGCACAGGCTTGCTCGATGACCAGCCGGGCCTGTCA
GCCGACGAACGCTTTGCCGGCTTTACGCCGCTTGAAGCCGCCGACTTGGCCAAGACCATCTGCTGGATTCACCAGCAGCC
TGCGCACGTCAATGTGCAGGAGATGACCCTGTTTCCGGTAGCGCAGAGCCTCTATGTTCGCGGTGTGCATTGCCGCGTGC
CCGAGACTTGCGCGCTCACCGCCGTTCCCTGGAAGAAGGCCAAGCCAATGACTTTGATGATCGACCATGAAATGGAGGCC
GTGGCGCGCCAGCTTTGGCCCTCGCCGCAGCGGCTGCAGCTGGCCACAGGCGGACTGTTCAACCGCGTGGTGCAGGTGCA
GTCCCCCGTCGGCACGACCTACCTGAAGCGCTTTACCGATGCGGCCAGCTCCGGCGACTTCCCCCCGCTGCCCACCAGCG
CCTCTCAGCGTTGCCTGGTCGCCTCCAACTGGCACGAACTCGCCCTGCGCGCGAGCGCGCGCGAGCCGCGCGCAGCGGTT
CCGTCCCTGGTTGCAGTGCAGACCGCGCTCGACCTGGTGGCGATGGAGGAGGCGCAGGGCGAGCCGCTGTATGACGCACT
CGTGGGCGATGGCCTTGGCGTCGGCGCGACGCTGCAAACGGTGACGGCATGGCTGGGCGCTCTGCACAGCCTGCCCCTTG
AGCCGCGCCCGCTGCTGTGGGCCGCCAGCGGACCATTCAAGGCCTTCAAGATCGATTTGCAGTACACGCGCATGTTGCCC
GAGATACCGCAAGCGTTGCACGCGGCAGGCGAGCGCTTCGTCGCCGACTACCTGCAACGCAGCGAGGAGCCCGTGCACGG
TGATCTCAACTCGCGCAACATCCTGAGCGCCGAAGGCGCGGTCTCCGTGATCGACTTCGAACAGGGCCACTTCGGCGAAG
GCGTGTATGACCTAGCCTATCTGCTGAGCGAGTACGTAATCCGCGACTTGCGCTTTGGGGTTGGTCCCGAAGCTACCATC
ACGGCGGCCTGGGAAGGCTATTGCCAAGCACGTGACCGCCACGCCAATGCGGAGACCTGGCGGCGCCTGCGTCTTCACCT
GGGATTCCAAACGCTGTATCGCCTAGTGGGGCCCAGCCGCAAGGTGTGGACCGGCCACCTGGACGATGTGATGAAGGATG
CGGTGCGGCGCTGGAGCACCGCAGAACTGTCGGCCTGGCTGCAATGA

Upstream 100 bases:

>100_bases
CATCCGCGAACACAACAAGAATCCCAAGCCCATCAAGTGGAAGTACGACGATCCATCACGGCGCATTCGACAGGTGCTTA
TTCAATGATGCAGTGGACTA

Downstream 100 bases:

>100_bases
CAGCGCGCGCCAACGTGCCGCTGGCAGCGAGCTATGTCGGCTTCTTCCTGCCGGCCGGAGTGCTCCTCAGCTACTTGCCG
CCGTTTCTGGCGGGCAAGGG

Product: aminoglycoside phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MVRDFAGVLVRRGAGTIVVLGSVAAQDAAPLMAAYAASRACVQQLVHCVRSDLHGSVVRVTCVQPGTTRTGLLDDQPGLS
ADERFAGFTPLEAADLAKTICWIHQQPAHVNVQEMTLFPVAQSLYVRGVHCRVPETCALTAVPWKKAKPMTLMIDHEMEA
VARQLWPSPQRLQLATGGLFNRVVQVQSPVGTTYLKRFTDAASSGDFPPLPTSASQRCLVASNWHELALRASAREPRAAV
PSLVAVQTALDLVAMEEAQGEPLYDALVGDGLGVGATLQTVTAWLGALHSLPLEPRPLLWAASGPFKAFKIDLQYTRMLP
EIPQALHAAGERFVADYLQRSEEPVHGDLNSRNILSAEGAVSVIDFEQGHFGEGVYDLAYLLSEYVIRDLRFGVGPEATI
TAAWEGYCQARDRHANAETWRRLRLHLGFQTLYRLVGPSRKVWTGHLDDVMKDAVRRWSTAELSAWLQ

Sequences:

>Translated_468_residues
MVRDFAGVLVRRGAGTIVVLGSVAAQDAAPLMAAYAASRACVQQLVHCVRSDLHGSVVRVTCVQPGTTRTGLLDDQPGLS
ADERFAGFTPLEAADLAKTICWIHQQPAHVNVQEMTLFPVAQSLYVRGVHCRVPETCALTAVPWKKAKPMTLMIDHEMEA
VARQLWPSPQRLQLATGGLFNRVVQVQSPVGTTYLKRFTDAASSGDFPPLPTSASQRCLVASNWHELALRASAREPRAAV
PSLVAVQTALDLVAMEEAQGEPLYDALVGDGLGVGATLQTVTAWLGALHSLPLEPRPLLWAASGPFKAFKIDLQYTRMLP
EIPQALHAAGERFVADYLQRSEEPVHGDLNSRNILSAEGAVSVIDFEQGHFGEGVYDLAYLLSEYVIRDLRFGVGPEATI
TAAWEGYCQARDRHANAETWRRLRLHLGFQTLYRLVGPSRKVWTGHLDDVMKDAVRRWSTAELSAWLQ
>Mature_468_residues
MVRDFAGVLVRRGAGTIVVLGSVAAQDAAPLMAAYAASRACVQQLVHCVRSDLHGSVVRVTCVQPGTTRTGLLDDQPGLS
ADERFAGFTPLEAADLAKTICWIHQQPAHVNVQEMTLFPVAQSLYVRGVHCRVPETCALTAVPWKKAKPMTLMIDHEMEA
VARQLWPSPQRLQLATGGLFNRVVQVQSPVGTTYLKRFTDAASSGDFPPLPTSASQRCLVASNWHELALRASAREPRAAV
PSLVAVQTALDLVAMEEAQGEPLYDALVGDGLGVGATLQTVTAWLGALHSLPLEPRPLLWAASGPFKAFKIDLQYTRMLP
EIPQALHAAGERFVADYLQRSEEPVHGDLNSRNILSAEGAVSVIDFEQGHFGEGVYDLAYLLSEYVIRDLRFGVGPEATI
TAAWEGYCQARDRHANAETWRRLRLHLGFQTLYRLVGPSRKVWTGHLDDVMKDAVRRWSTAELSAWLQ

Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787820, Length=126, Percent_Identity=30.952380952381, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.276 [H]

Molecular weight: Translated: 51226; Mature: 51226

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRDFAGVLVRRGAGTIVVLGSVAAQDAAPLMAAYAASRACVQQLVHCVRSDLHGSVVRV
CCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TCVQPGTTRTGLLDDQPGLSADERFAGFTPLEAADLAKTICWIHQQPAHVNVQEMTLFPV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AQSLYVRGVHCRVPETCALTAVPWKKAKPMTLMIDHEMEAVARQLWPSPQRLQLATGGLF
HHHHHHCCEEECCCCCCEEEECCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEHHCHHH
NRVVQVQSPVGTTYLKRFTDAASSGDFPPLPTSASQRCLVASNWHELALRASAREPRAAV
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCHHH
PSLVAVQTALDLVAMEEAQGEPLYDALVGDGLGVGATLQTVTAWLGALHSLPLEPRPLLW
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEE
AASGPFKAFKIDLQYTRMLPEIPQALHAAGERFVADYLQRSEEPVHGDLNSRNILSAEGA
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCC
VSVIDFEQGHFGEGVYDLAYLLSEYVIRDLRFGVGPEATITAAWEGYCQARDRHANAETW
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCHHHH
RRLRLHLGFQTLYRLVGPSRKVWTGHLDDVMKDAVRRWSTAELSAWLQ
HHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MVRDFAGVLVRRGAGTIVVLGSVAAQDAAPLMAAYAASRACVQQLVHCVRSDLHGSVVRV
CCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TCVQPGTTRTGLLDDQPGLSADERFAGFTPLEAADLAKTICWIHQQPAHVNVQEMTLFPV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AQSLYVRGVHCRVPETCALTAVPWKKAKPMTLMIDHEMEAVARQLWPSPQRLQLATGGLF
HHHHHHCCEEECCCCCCEEEECCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEHHCHHH
NRVVQVQSPVGTTYLKRFTDAASSGDFPPLPTSASQRCLVASNWHELALRASAREPRAAV
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCHHH
PSLVAVQTALDLVAMEEAQGEPLYDALVGDGLGVGATLQTVTAWLGALHSLPLEPRPLLW
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEE
AASGPFKAFKIDLQYTRMLPEIPQALHAAGERFVADYLQRSEEPVHGDLNSRNILSAEGA
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCC
VSVIDFEQGHFGEGVYDLAYLLSEYVIRDLRFGVGPEATITAAWEGYCQARDRHANAETW
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCHHHH
RRLRLHLGFQTLYRLVGPSRKVWTGHLDDVMKDAVRRWSTAELSAWLQ
HHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]