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The map label for this gene is ychM [C]

Identifier: 121610228

GI number: 121610228

Start: 3667025

End: 3668740

Strand: Direct

Name: ychM [C]

Synonym: Veis_3287

Alternate gene names: 121610228

Gene position: 3667025-3668740 (Clockwise)

Preceding gene: 121610227

Following gene: 121610229

Centisome position: 65.87

GC content: 67.31

Gene sequence:

>1716_bases
ATGAATTTGTCATCGCTGACCCGCTGGCTGCCCTTTCTCGCTTGGCCCCGACCCGACCGCCAACTGCTCAAAGGGGAGTT
CTGGGCCGGCATGACGGTGGGGCTGTTGCTGGTGCCGCAAGGCGTGGCCTATGCCGCGCTGGCCGGTATGCCCTTGGTCA
CCGGGATTTATGCCTCGTTGATTCCGGCATTGGTCGCCGTGCTGTTCAGTTCCTCCACCCGCCTGGGGGTGGGGCCTACG
GCACTGACCAGTTTGTTGATCGGGGCCGCGCTCACCGGGCTGGCCGAGCCCGGCAGCGCCCAGTGGGTGGCGCTGGCGGC
GTGGATGGCGCTGTTCTCGGGCTTGTTGCAGTTGGTGATGGGGTTGGCGCGTTTTGGCTGGCTGCTCAATCTGATCACCT
CGCCGGTGCTCAGCGGTTTTACGCAGGCGGCTGCGCTGCTGATCCTGGGCTCGCAACTGCGATCGCTCACCGGCCTGCGG
GCCACCGACTGGGGGGCGCTGTGGTCCACACCATCGCCGGGTTTGTTTGACCTGACTGCGGCGGCCTTCGGCCTGGGCAG
CCTGGCGCTGTTGCTGTTGGCGCGGCGCTGGCGGCCGCATTTTCCGACCGCCATCGTGGTGGTGGGGGCGGCTGGCGCAT
CGAGTTGGGCCTTGGGCTATGCCGACGCCGGTGGCGCTGTGGTGGGCGCATTGCCTTCGGGTCTGCCCGCCCTGTACTGG
CCGGGCGCTCTGCCCTGGTCCAGTTTCTCGGCCCTGGTGATGCCGGTGCTCGTGGTGACGCTGGTGAGTTTTCTGGAGAC
AGCCTCCAGTGCCAAGGTGGAGAGCCAGCGCTCGGGCGTGCAATGGGACGAAAACCAGGATCTGATCGGCCAGGGTCTGG
GCAAGATCAGCAGCGGTCTGTGCGGCAGCTTTGCCACCAGCGCTTCGTTTTCGCGCTCGGCCATCAACCTGTATGCCGGC
GCCAAGAGCGGCTGGGCCACGTTGTTTGCCATCGCGCTGGTGCTGCTGGTGCTGCTGTGGCTGACACCGGCGCTATACCA
TGTGCCGCAGTCCGTGCTGGCGGCCGTGGTGGTCACGGCGGTGACCAGCCTGATCCGGCCCGCAGTGCTGACGAGGCTGT
GGCGGGTGTCGCATGTGGAGGCCGTGATCGGCGGCGTGACCTTTGCGCTGACGCTGGCCACGGCACCGCGCATGTACTGG
GGCGTGCTGGCGGGCCTGCTGATGAATCTGAGCCATTTTCTGTACCTGCGGCTGCACCCCCGCATCATCGAGGCGGGCCT
GCATCCGGATGGCAGCATGCGCGATCGCCATCTGTGGCAGTTGCCCCCGCTCGCGCCACGGCTGCTGGCGTTGCGCATGG
ATGCCGCGCTCGATTTTGCCTCCGCCAACGCGTTGGAGCGGCGGGTGACCGAGCACCTGGCTGCGCATCCGCAGGTGCTG
CACCTGTGCCTGTTGGCCCAGTCCATCAACCGCATCGACGTGACCGGGGTGGAGACCTTTGCGCAGTTGCTGGCGCTGAT
GCAGTCCAGGGGCGGGATGCTGCACCTGAGCGGCCTGAAACTGCCGGTAGAGCAGGTGCTGCGCCAGGCCGGACTGCTGG
CGCCGTGCGCCGGGCTGGCCATGTACCGCACCGACGCCGAGGCGCTGCAGGCGTTGCAACAACTGTCGCAATTGCCACGA
CCGGATCTCGAGCCTGGGCCGATGGCCCGGGTCTGA

Upstream 100 bases:

>100_bases
GCCGGGTCGGACGGCGCTGAAGTGTTTGTAGGACGGCGCCGCCAAGTTCCCCGGCCTGCCCGCAAACCAAGGCCGACATG
GTGATGCGCGACAATCGGCC

Downstream 100 bases:

>100_bases
GCGCCGCCGGATGGCTTTGTGCCGTCTGACGCACTGCTACACTGCAAGCCAACTTTTTGGGCTTGACCGGTGTCTGACTC
TGCGGCCTCTTCTTTCGTGG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MNLSSLTRWLPFLAWPRPDRQLLKGEFWAGMTVGLLLVPQGVAYAALAGMPLVTGIYASLIPALVAVLFSSSTRLGVGPT
ALTSLLIGAALTGLAEPGSAQWVALAAWMALFSGLLQLVMGLARFGWLLNLITSPVLSGFTQAAALLILGSQLRSLTGLR
ATDWGALWSTPSPGLFDLTAAAFGLGSLALLLLARRWRPHFPTAIVVVGAAGASSWALGYADAGGAVVGALPSGLPALYW
PGALPWSSFSALVMPVLVVTLVSFLETASSAKVESQRSGVQWDENQDLIGQGLGKISSGLCGSFATSASFSRSAINLYAG
AKSGWATLFAIALVLLVLLWLTPALYHVPQSVLAAVVVTAVTSLIRPAVLTRLWRVSHVEAVIGGVTFALTLATAPRMYW
GVLAGLLMNLSHFLYLRLHPRIIEAGLHPDGSMRDRHLWQLPPLAPRLLALRMDAALDFASANALERRVTEHLAAHPQVL
HLCLLAQSINRIDVTGVETFAQLLALMQSRGGMLHLSGLKLPVEQVLRQAGLLAPCAGLAMYRTDAEALQALQQLSQLPR
PDLEPGPMARV

Sequences:

>Translated_571_residues
MNLSSLTRWLPFLAWPRPDRQLLKGEFWAGMTVGLLLVPQGVAYAALAGMPLVTGIYASLIPALVAVLFSSSTRLGVGPT
ALTSLLIGAALTGLAEPGSAQWVALAAWMALFSGLLQLVMGLARFGWLLNLITSPVLSGFTQAAALLILGSQLRSLTGLR
ATDWGALWSTPSPGLFDLTAAAFGLGSLALLLLARRWRPHFPTAIVVVGAAGASSWALGYADAGGAVVGALPSGLPALYW
PGALPWSSFSALVMPVLVVTLVSFLETASSAKVESQRSGVQWDENQDLIGQGLGKISSGLCGSFATSASFSRSAINLYAG
AKSGWATLFAIALVLLVLLWLTPALYHVPQSVLAAVVVTAVTSLIRPAVLTRLWRVSHVEAVIGGVTFALTLATAPRMYW
GVLAGLLMNLSHFLYLRLHPRIIEAGLHPDGSMRDRHLWQLPPLAPRLLALRMDAALDFASANALERRVTEHLAAHPQVL
HLCLLAQSINRIDVTGVETFAQLLALMQSRGGMLHLSGLKLPVEQVLRQAGLLAPCAGLAMYRTDAEALQALQQLSQLPR
PDLEPGPMARV
>Mature_571_residues
MNLSSLTRWLPFLAWPRPDRQLLKGEFWAGMTVGLLLVPQGVAYAALAGMPLVTGIYASLIPALVAVLFSSSTRLGVGPT
ALTSLLIGAALTGLAEPGSAQWVALAAWMALFSGLLQLVMGLARFGWLLNLITSPVLSGFTQAAALLILGSQLRSLTGLR
ATDWGALWSTPSPGLFDLTAAAFGLGSLALLLLARRWRPHFPTAIVVVGAAGASSWALGYADAGGAVVGALPSGLPALYW
PGALPWSSFSALVMPVLVVTLVSFLETASSAKVESQRSGVQWDENQDLIGQGLGKISSGLCGSFATSASFSRSAINLYAG
AKSGWATLFAIALVLLVLLWLTPALYHVPQSVLAAVVVTAVTSLIRPAVLTRLWRVSHVEAVIGGVTFALTLATAPRMYW
GVLAGLLMNLSHFLYLRLHPRIIEAGLHPDGSMRDRHLWQLPPLAPRLLALRMDAALDFASANALERRVTEHLAAHPQVL
HLCLLAQSINRIDVTGVETFAQLLALMQSRGGMLHLSGLKLPVEQVLRQAGLLAPCAGLAMYRTDAEALQALQQLSQLPR
PDLEPGPMARV

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=602, Percent_Identity=30.0664451827243, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI262206075, Length=602, Percent_Identity=30.0664451827243, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI262206069, Length=602, Percent_Identity=30.0664451827243, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI262206063, Length=602, Percent_Identity=30.0664451827243, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI45827800, Length=504, Percent_Identity=27.1825396825397, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI39752683, Length=504, Percent_Identity=27.1825396825397, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI45827802, Length=423, Percent_Identity=29.0780141843972, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI269784651, Length=382, Percent_Identity=28.7958115183246, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94721255, Length=420, Percent_Identity=29.7619047619048, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI94721259, Length=420, Percent_Identity=29.7619047619048, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI94721253, Length=420, Percent_Identity=29.7619047619048, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI94721257, Length=420, Percent_Identity=29.7619047619048, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI4505697, Length=421, Percent_Identity=26.603325415677, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4557535, Length=414, Percent_Identity=29.951690821256, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI20336282, Length=449, Percent_Identity=25.8351893095768, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI16306483, Length=449, Percent_Identity=25.8351893095768, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI65506789, Length=427, Percent_Identity=30.2107728337237, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI100913030, Length=434, Percent_Identity=24.4239631336406, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI45827804, Length=264, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI47131207, Length=462, Percent_Identity=27.7056277056277, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI20336272, Length=462, Percent_Identity=27.7056277056277, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI16418413, Length=417, Percent_Identity=24.220623501199, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI217272867, Length=417, Percent_Identity=24.220623501199, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081859, Length=327, Percent_Identity=28.4403669724771, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551690, Length=482, Percent_Identity=23.8589211618257, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17566848, Length=577, Percent_Identity=25.3032928942808, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI86564196, Length=639, Percent_Identity=21.7527386541471, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI86565215, Length=454, Percent_Identity=26.8722466960352, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17562578, Length=649, Percent_Identity=22.9583975346687, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193203292, Length=525, Percent_Identity=23.4285714285714, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI86564876, Length=555, Percent_Identity=21.2612612612613, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI86565213, Length=183, Percent_Identity=30.6010928961749, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319771, Length=444, Percent_Identity=25.4504504504505, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323121, Length=447, Percent_Identity=25.7270693512304, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325260, Length=438, Percent_Identity=22.1461187214612, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24649801, Length=608, Percent_Identity=26.4802631578947, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24651449, Length=482, Percent_Identity=27.1784232365145, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21358229, Length=573, Percent_Identity=23.9092495636998, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI19922482, Length=527, Percent_Identity=26.1859582542694, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647160, Length=596, Percent_Identity=23.993288590604, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21355087, Length=596, Percent_Identity=23.993288590604, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI85815873, Length=512, Percent_Identity=26.171875, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24663084, Length=467, Percent_Identity=27.6231263383298, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI21357695, Length=467, Percent_Identity=27.6231263383298, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24666186, Length=438, Percent_Identity=23.7442922374429, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21358633, Length=455, Percent_Identity=25.0549450549451, Blast_Score=117, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60503; Mature: 60503

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSSLTRWLPFLAWPRPDRQLLKGEFWAGMTVGLLLVPQGVAYAALAGMPLVTGIYASL
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHH
IPALVAVLFSSSTRLGVGPTALTSLLIGAALTGLAEPGSAQWVALAAWMALFSGLLQLVM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GLARFGWLLNLITSPVLSGFTQAAALLILGSQLRSLTGLRATDWGALWSTPSPGLFDLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AAFGLGSLALLLLARRWRPHFPTAIVVVGAAGASSWALGYADAGGAVVGALPSGLPALYW
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
PGALPWSSFSALVMPVLVVTLVSFLETASSAKVESQRSGVQWDENQDLIGQGLGKISSGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCH
CGSFATSASFSRSAINLYAGAKSGWATLFAIALVLLVLLWLTPALYHVPQSVLAAVVVTA
HHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTSLIRPAVLTRLWRVSHVEAVIGGVTFALTLATAPRMYWGVLAGLLMNLSHFLYLRLHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RIIEAGLHPDGSMRDRHLWQLPPLAPRLLALRMDAALDFASANALERRVTEHLAAHPQVL
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
HLCLLAQSINRIDVTGVETFAQLLALMQSRGGMLHLSGLKLPVEQVLRQAGLLAPCAGLA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCHHHHHH
MYRTDAEALQALQQLSQLPRPDLEPGPMARV
HHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLSSLTRWLPFLAWPRPDRQLLKGEFWAGMTVGLLLVPQGVAYAALAGMPLVTGIYASL
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHH
IPALVAVLFSSSTRLGVGPTALTSLLIGAALTGLAEPGSAQWVALAAWMALFSGLLQLVM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GLARFGWLLNLITSPVLSGFTQAAALLILGSQLRSLTGLRATDWGALWSTPSPGLFDLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AAFGLGSLALLLLARRWRPHFPTAIVVVGAAGASSWALGYADAGGAVVGALPSGLPALYW
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
PGALPWSSFSALVMPVLVVTLVSFLETASSAKVESQRSGVQWDENQDLIGQGLGKISSGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCH
CGSFATSASFSRSAINLYAGAKSGWATLFAIALVLLVLLWLTPALYHVPQSVLAAVVVTA
HHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTSLIRPAVLTRLWRVSHVEAVIGGVTFALTLATAPRMYWGVLAGLLMNLSHFLYLRLHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RIIEAGLHPDGSMRDRHLWQLPPLAPRLLALRMDAALDFASANALERRVTEHLAAHPQVL
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
HLCLLAQSINRIDVTGVETFAQLLALMQSRGGMLHLSGLKLPVEQVLRQAGLLAPCAGLA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCHHHHHH
MYRTDAEALQALQQLSQLPRPDLEPGPMARV
HHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]