Click here to switch to the map view.

The map label for this gene is 121610071

Identifier: 121610071

GI number: 121610071

Start: 3477387

End: 3478637

Strand: Direct

Name: 121610071

Synonym: Veis_3129

Alternate gene names: NA

Gene position: 3477387-3478637 (Clockwise)

Preceding gene: 121610070

Following gene: 121610072

Centisome position: 62.47

GC content: 58.75

Gene sequence:

>1251_bases
ATGGCGTCTGAGTGGGCGACTGCGACGATTGGCGATGTTGCCAAGATAAAGCACGGCTTCGCTTTCAAGGGCGAGTTTTT
CACGGATGAAGTGACGCCGAATGTCTTGGTCACGCCCGGAAACTTTGCGATCGGCGGCGGCTTCCAGATTGGCAAGCCTA
AGTATTACGCCGGGCCGCTACCTGATGACTATGCGCTGACGGAAGGTGAAGTTGTCGTCACGATGACGGACTTGAGCAAG
GCATCCGACACGCTTGGTTATGCGGCAAAGGTTCCAAGCGTACCCGGCGTGACTTACTGGCACAACCAGCGAATCGGCTT
GCTGCAAGTCACGGACAAGCAGCGCGCTTGCAAAGATTGGCTGCACTACCTGATGCGAACACACGAATACCGCGCATGGG
TTGTCGGTTCTGCATCAGGCACAACGGTCAAGCACACATCGCCGTCACGAATCGAGAGCTTTTCGTTCAAGCTCCCGCCG
CTCGAAGAACAACGCGCCATTGCCGAAACACTCGGCTCACTCGACGACCGCATCGACAATCTACGCCAGACCAACGCCAC
GCTGGAAGCCATCGCTGCCGCGCTATTCAAGTCTTGGTTCGTGGACTTTGACGGCGTTTCCGCCACGGATATGCGGGAAT
CGGAACTGGGCTTGATTCCGAAGGGGTGGCGGATTGGCTCCTTTGACGAGGCCATCGAAATCCTCGGTGGCGGCACACCG
AAAACCTCCATCGCTGACTACTGGAGCGGCGATGTGCCGTGGTTTTCCGTTGTGGACGCACCCGGCAGTGGCCAAGTGTT
CGTGCTGGATACCGAAAAGAAAATCACCGCGCTCGGCTTGCAAAACTGCTCGGCCAAGCTGCTGCCGGAAATGACCACCA
TCATTTCGGCACGTGGCACAGTGGGAAAGGTGGCGATGACCGGCGTGCCGATGGCGATGAATCAGTCGTGCTACGCGCTG
CGTCCCAGGCAGCAAAGCGGCGAAGCCTTCGTCTATTTCTCAACGCTGCGCTTCGTCGAGCATCTGCAACGCATCGCCCA
CGGTGCGGTGTTCGACACCATCACACGTGACAGCTTCAAGCAGGTCACGACTTGCCTGCCGCCCGATGAAGTTATCGCCG
GGTTTGCCGAAATTGCGAACCCGCTGCTCGAACGCATCCGCATCAACGGACAGCAAGCTGCCATCCTCGCCGCCCTGCGC
GACGCGCTTCTGCCGCGCCTTATCTCCGGCCAACTTCGGGTGGCGCAATGA

Upstream 100 bases:

>100_bases
GCAGACAAGATGCAGCGGCTGACCACGCAGTTGTTTGAAAAGACGAAGCGCGGCGCGGAACTGGATGCCGTCATCTGCGA
GAAACTGGGGGCGCTTGGTT

Downstream 100 bases:

>100_bases
GCCTGGACTGGTGCCCCGGCATCCGCGAAGCCTGCGTGCATTGGCGCGACGCGCCGATGTTGCAGCAGACCTTCGAGGCG
CTGGAGCGCACCTTGGAGCA

Product: restriction modification system DNA specificity subunit

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MASEWATATIGDVAKIKHGFAFKGEFFTDEVTPNVLVTPGNFAIGGGFQIGKPKYYAGPLPDDYALTEGEVVVTMTDLSK
ASDTLGYAAKVPSVPGVTYWHNQRIGLLQVTDKQRACKDWLHYLMRTHEYRAWVVGSASGTTVKHTSPSRIESFSFKLPP
LEEQRAIAETLGSLDDRIDNLRQTNATLEAIAAALFKSWFVDFDGVSATDMRESELGLIPKGWRIGSFDEAIEILGGGTP
KTSIADYWSGDVPWFSVVDAPGSGQVFVLDTEKKITALGLQNCSAKLLPEMTTIISARGTVGKVAMTGVPMAMNQSCYAL
RPRQQSGEAFVYFSTLRFVEHLQRIAHGAVFDTITRDSFKQVTTCLPPDEVIAGFAEIANPLLERIRINGQQAAILAALR
DALLPRLISGQLRVAQ

Sequences:

>Translated_416_residues
MASEWATATIGDVAKIKHGFAFKGEFFTDEVTPNVLVTPGNFAIGGGFQIGKPKYYAGPLPDDYALTEGEVVVTMTDLSK
ASDTLGYAAKVPSVPGVTYWHNQRIGLLQVTDKQRACKDWLHYLMRTHEYRAWVVGSASGTTVKHTSPSRIESFSFKLPP
LEEQRAIAETLGSLDDRIDNLRQTNATLEAIAAALFKSWFVDFDGVSATDMRESELGLIPKGWRIGSFDEAIEILGGGTP
KTSIADYWSGDVPWFSVVDAPGSGQVFVLDTEKKITALGLQNCSAKLLPEMTTIISARGTVGKVAMTGVPMAMNQSCYAL
RPRQQSGEAFVYFSTLRFVEHLQRIAHGAVFDTITRDSFKQVTTCLPPDEVIAGFAEIANPLLERIRINGQQAAILAALR
DALLPRLISGQLRVAQ
>Mature_415_residues
ASEWATATIGDVAKIKHGFAFKGEFFTDEVTPNVLVTPGNFAIGGGFQIGKPKYYAGPLPDDYALTEGEVVVTMTDLSKA
SDTLGYAAKVPSVPGVTYWHNQRIGLLQVTDKQRACKDWLHYLMRTHEYRAWVVGSASGTTVKHTSPSRIESFSFKLPPL
EEQRAIAETLGSLDDRIDNLRQTNATLEAIAAALFKSWFVDFDGVSATDMRESELGLIPKGWRIGSFDEAIEILGGGTPK
TSIADYWSGDVPWFSVVDAPGSGQVFVLDTEKKITALGLQNCSAKLLPEMTTIISARGTVGKVAMTGVPMAMNQSCYALR
PRQQSGEAFVYFSTLRFVEHLQRIAHGAVFDTITRDSFKQVTTCLPPDEVIAGFAEIANPLLERIRINGQQAAILAALRD
ALLPRLISGQLRVAQ

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 45382; Mature: 45251

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEWATATIGDVAKIKHGFAFKGEFFTDEVTPNVLVTPGNFAIGGGFQIGKPKYYAGPL
CCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCEEEECCCEEECCCEECCCCCEECCCC
PDDYALTEGEVVVTMTDLSKASDTLGYAAKVPSVPGVTYWHNQRIGLLQVTDKQRACKDW
CCCCEECCCCEEEEEECCCHHHHHCCHHCCCCCCCCEEEEECCCEEEEEECCHHHHHHHH
LHYLMRTHEYRAWVVGSASGTTVKHTSPSRIESFSFKLPPLEEQRAIAETLGSLDDRIDN
HHHHHHCCCCEEEEEECCCCCEEECCCCCHHHHCEECCCCCHHHHHHHHHHHHHHHHHHH
LRQTNATLEAIAAALFKSWFVDFDGVSATDMRESELGLIPKGWRIGSFDEAIEILGGGTP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCC
KTSIADYWSGDVPWFSVVDAPGSGQVFVLDTEKKITALGLQNCSAKLLPEMTTIISARGT
CCCHHHCCCCCCCEEEEEECCCCCEEEEEECCCCEEEHHHCCCCHHHHHHHHHHHHCCCC
VGKVAMTGVPMAMNQSCYALRPRQQSGEAFVYFSTLRFVEHLQRIAHGAVFDTITRDSFK
CCEEEECCCCHHHCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVTTCLPPDEVIAGFAEIANPLLERIRINGQQAAILAALRDALLPRLISGQLRVAQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure 
ASEWATATIGDVAKIKHGFAFKGEFFTDEVTPNVLVTPGNFAIGGGFQIGKPKYYAGPL
CCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCEEEECCCEEECCCEECCCCCEECCCC
PDDYALTEGEVVVTMTDLSKASDTLGYAAKVPSVPGVTYWHNQRIGLLQVTDKQRACKDW
CCCCEECCCCEEEEEECCCHHHHHCCHHCCCCCCCCEEEEECCCEEEEEECCHHHHHHHH
LHYLMRTHEYRAWVVGSASGTTVKHTSPSRIESFSFKLPPLEEQRAIAETLGSLDDRIDN
HHHHHHCCCCEEEEEECCCCCEEECCCCCHHHHCEECCCCCHHHHHHHHHHHHHHHHHHH
LRQTNATLEAIAAALFKSWFVDFDGVSATDMRESELGLIPKGWRIGSFDEAIEILGGGTP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCC
KTSIADYWSGDVPWFSVVDAPGSGQVFVLDTEKKITALGLQNCSAKLLPEMTTIISARGT
CCCHHHCCCCCCCEEEEEECCCCCEEEEEECCCCEEEHHHCCCCHHHHHHHHHHHHCCCC
VGKVAMTGVPMAMNQSCYALRPRQQSGEAFVYFSTLRFVEHLQRIAHGAVFDTITRDSFK
CCEEEECCCCHHHCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVTTCLPPDEVIAGFAEIANPLLERIRINGQQAAILAALRDALLPRLISGQLRVAQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]