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The map label for this gene is hsdM [C]

Identifier: 121610070

GI number: 121610070

Start: 3475841

End: 3477397

Strand: Direct

Name: hsdM [C]

Synonym: Veis_3128

Alternate gene names: 121610070

Gene position: 3475841-3477397 (Clockwise)

Preceding gene: 121610069

Following gene: 121610071

Centisome position: 62.44

GC content: 61.79

Gene sequence:

>1557_bases
ATGGCACAGAACGACAACAACGGCGGCAACCTGGGCTTCGAAGCGGAACTGTTCAAGACCGCCGACAAACTGCGCGGCAA
CATGGAACCCAGCGACTACAAGCACGTCGCGCTGGGCCTGATCTTCCTGAAGTACATCTCCGATGCTTTCGAGGCGCGCC
ACGCGCAACTGCTGGCCGAAGACGCCGCTGCCGCCGAGGACAAGGACGAATACCTCGCCGACAACATCTTCTGGGTACCC
AGGGAAGCACGCTGGTCGCATCTGCAAGCCAATGCCAAGCAGAGCAGCATCGGCACACTGATCGACGATGCGATGCGCGC
CATCGAGAGGGACAACGAATCCCTGAAAGGCGTGCTACCCAAGGACTACGCCCGCCCGGCACTCAACAAGGTGATGCTGG
GCGAGTTGATCGACCTGATTTCCGGCATCGCGCTGAACGAAGGCAACGACAAGTCCAAGGACGTGCTGGGCCGCGTCTAT
GAATACTTCCTCGGCCAGTTCGCCGGCGCGGAAGGCAAGCGCGGCGGCGAGTTCTACACGCCGCGCTCCGTGGTGCGCAC
GCTGGTGGAAATGCTGGAACCCTACACCGGGCGCGTCTATGACCCCTGCTGCGGCAGCGGCGGCATGTTCGTGCAAAGCG
AGAAATTCGTCGCCGAACACGGCGGGCGCATCGGCGACATCGCCATCTACGGGCAGGAAAGCAACTACACGACGTGGCGC
CTGGCGAAGATGAACTTGGCCGTGCGCGGCATTGACAGCGACATCAAGTGGAACAACGAAGGCAGTTTCCACAAGGACGA
ACTGCGCGACCTCAAGGCCGATTTCATCCTCGCCAACCCGCCGTTCAACATTTCCGACTGGGGCGGGGGACGCCTGCGCG
AGGACGTGCGCTGGGCTTTCGGCGCACCGCCCGCAGGCAATGCCAACTATGCGTGGTTGCAGCACATTTTTCACCACCTC
AGCCCGCACGGCTTTGCGGGCGTGGTGTTGGCAAACGGTTCGATGAGTTCGCAGCAGAGCGGCGAAGGCGACATCCGCAA
GGCGATGATCGAGGCGAACGTCGTGGACTGCATGGTCGCGCTGCCTGGCCAGTTGTTCTATTCCACGCAGATTCCGGCCT
GCCTGTGGATTCTGTCGAAAGACCGCAGCAATGGGCTGGTGAAGAAAACCAAGCTGCGCGACCGGCGCGGTGAAGTGCTG
TTCATCGACGCGCGCAAGATGGGCGTGCTGGTGGATCGCACGCGGCGCGAACTGACCAACGAGGAAATTGGCAGGATCGC
CGCCACCTACCACGCATGGCGCGGCGAAGCCGACGCGGGCGAATATTCGGATATTCCGGGCTTCTGCAAATCTGCCACGC
TCGACGCGATCCGTAAGCACGATCACGTTCTCACGCCGGGACGCTACGTCGGCGCGGAAGCGCAAGAAGATGACGGCGAG
GCATTCGCAGACAAGATGCAGCGGCTGACCACGCAGTTGTTTGAAAAGACGAAGCGCGGCGCGGAACTGGATGCCGTCAT
CTGCGAGAAACTGGGGGCGCTTGGTTATGGCGTCTGA

Upstream 100 bases:

>100_bases
TCAAGCTCAAGCGCGACGGGTACGGCGTGGAGCCGGTGGCGTTGGCAACCGAATTTCTGGTAGTGCTGAACGACCCGGCA
CGCGAATAGGACAAAACACG

Downstream 100 bases:

>100_bases
GTGGGCGACTGCGACGATTGGCGATGTTGCCAAGATAAAGCACGGCTTCGCTTTCAAGGGCGAGTTTTTCACGGATGAAG
TGACGCCGAATGTCTTGGTC

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MAQNDNNGGNLGFEAELFKTADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHAQLLAEDAAAAEDKDEYLADNIFWVP
REARWSHLQANAKQSSIGTLIDDAMRAIERDNESLKGVLPKDYARPALNKVMLGELIDLISGIALNEGNDKSKDVLGRVY
EYFLGQFAGAEGKRGGEFYTPRSVVRTLVEMLEPYTGRVYDPCCGSGGMFVQSEKFVAEHGGRIGDIAIYGQESNYTTWR
LAKMNLAVRGIDSDIKWNNEGSFHKDELRDLKADFILANPPFNISDWGGGRLREDVRWAFGAPPAGNANYAWLQHIFHHL
SPHGFAGVVLANGSMSSQQSGEGDIRKAMIEANVVDCMVALPGQLFYSTQIPACLWILSKDRSNGLVKKTKLRDRRGEVL
FIDARKMGVLVDRTRRELTNEEIGRIAATYHAWRGEADAGEYSDIPGFCKSATLDAIRKHDHVLTPGRYVGAEAQEDDGE
AFADKMQRLTTQLFEKTKRGAELDAVICEKLGALGYGV

Sequences:

>Translated_518_residues
MAQNDNNGGNLGFEAELFKTADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHAQLLAEDAAAAEDKDEYLADNIFWVP
REARWSHLQANAKQSSIGTLIDDAMRAIERDNESLKGVLPKDYARPALNKVMLGELIDLISGIALNEGNDKSKDVLGRVY
EYFLGQFAGAEGKRGGEFYTPRSVVRTLVEMLEPYTGRVYDPCCGSGGMFVQSEKFVAEHGGRIGDIAIYGQESNYTTWR
LAKMNLAVRGIDSDIKWNNEGSFHKDELRDLKADFILANPPFNISDWGGGRLREDVRWAFGAPPAGNANYAWLQHIFHHL
SPHGFAGVVLANGSMSSQQSGEGDIRKAMIEANVVDCMVALPGQLFYSTQIPACLWILSKDRSNGLVKKTKLRDRRGEVL
FIDARKMGVLVDRTRRELTNEEIGRIAATYHAWRGEADAGEYSDIPGFCKSATLDAIRKHDHVLTPGRYVGAEAQEDDGE
AFADKMQRLTTQLFEKTKRGAELDAVICEKLGALGYGV
>Mature_517_residues
AQNDNNGGNLGFEAELFKTADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHAQLLAEDAAAAEDKDEYLADNIFWVPR
EARWSHLQANAKQSSIGTLIDDAMRAIERDNESLKGVLPKDYARPALNKVMLGELIDLISGIALNEGNDKSKDVLGRVYE
YFLGQFAGAEGKRGGEFYTPRSVVRTLVEMLEPYTGRVYDPCCGSGGMFVQSEKFVAEHGGRIGDIAIYGQESNYTTWRL
AKMNLAVRGIDSDIKWNNEGSFHKDELRDLKADFILANPPFNISDWGGGRLREDVRWAFGAPPAGNANYAWLQHIFHHLS
PHGFAGVVLANGSMSSQQSGEGDIRKAMIEANVVDCMVALPGQLFYSTQIPACLWILSKDRSNGLVKKTKLRDRRGEVLF
IDARKMGVLVDRTRRELTNEEIGRIAATYHAWRGEADAGEYSDIPGFCKSATLDAIRKHDHVLTPGRYVGAEAQEDDGEA
FADKMQRLTTQLFEKTKRGAELDAVICEKLGALGYGV

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=386, Percent_Identity=23.3160621761658, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57441; Mature: 57310

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNDNNGGNLGFEAELFKTADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHAQLLAE
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAAAEDKDEYLADNIFWVPREARWSHLQANAKQSSIGTLIDDAMRAIERDNESLKGVLP
HHHCCCCCHHHHHCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCC
KDYARPALNKVMLGELIDLISGIALNEGNDKSKDVLGRVYEYFLGQFAGAEGKRGGEFYT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PRSVVRTLVEMLEPYTGRVYDPCCGSGGMFVQSEKFVAEHGGRIGDIAIYGQESNYTTWR
HHHHHHHHHHHHCCCCCCEECCCCCCCCCEEECCHHHHHCCCCEEEEEEEECCCCCCEEE
LAKMNLAVRGIDSDIKWNNEGSFHKDELRDLKADFILANPPFNISDWGGGRLREDVRWAF
EEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHC
GAPPAGNANYAWLQHIFHHLSPHGFAGVVLANGSMSSQQSGEGDIRKAMIEANVVDCMVA
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LPGQLFYSTQIPACLWILSKDRSNGLVKKTKLRDRRGEVLFIDARKMGVLVDRTRRELTN
CCCHHEECCCCCEEEEEEECCCCCCCEEHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
EEIGRIAATYHAWRGEADAGEYSDIPGFCKSATLDAIRKHDHVLTPGRYVGAEAQEDDGE
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHH
AFADKMQRLTTQLFEKTKRGAELDAVICEKLGALGYGV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQNDNNGGNLGFEAELFKTADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHAQLLAE
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAAAEDKDEYLADNIFWVPREARWSHLQANAKQSSIGTLIDDAMRAIERDNESLKGVLP
HHHCCCCCHHHHHCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCC
KDYARPALNKVMLGELIDLISGIALNEGNDKSKDVLGRVYEYFLGQFAGAEGKRGGEFYT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PRSVVRTLVEMLEPYTGRVYDPCCGSGGMFVQSEKFVAEHGGRIGDIAIYGQESNYTTWR
HHHHHHHHHHHHCCCCCCEECCCCCCCCCEEECCHHHHHCCCCEEEEEEEECCCCCCEEE
LAKMNLAVRGIDSDIKWNNEGSFHKDELRDLKADFILANPPFNISDWGGGRLREDVRWAF
EEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHC
GAPPAGNANYAWLQHIFHHLSPHGFAGVVLANGSMSSQQSGEGDIRKAMIEANVVDCMVA
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LPGQLFYSTQIPACLWILSKDRSNGLVKKTKLRDRRGEVLFIDARKMGVLVDRTRRELTN
CCCHHEECCCCCEEEEEEECCCCCCCEEHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
EEIGRIAATYHAWRGEADAGEYSDIPGFCKSATLDAIRKHDHVLTPGRYVGAEAQEDDGE
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHH
AFADKMQRLTTQLFEKTKRGAELDAVICEKLGALGYGV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]