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The map label for this gene is hsdM [C]

Identifier: 121609950

GI number: 121609950

Start: 3354949

End: 3356511

Strand: Direct

Name: hsdM [C]

Synonym: Veis_3006

Alternate gene names: 121609950

Gene position: 3354949-3356511 (Clockwise)

Preceding gene: 121609949

Following gene: 121609951

Centisome position: 60.27

GC content: 61.68

Gene sequence:

>1563_bases
ATGGCACAGAACGACACGAACAAAAAAGGCAGCAACCTCGGCTTCGAGGCCGAGATGTTCAAAGCCGCCGACAAACTGCG
CGGCAACATGGAGCCATCCGACTACAAGCATGTCGCGCTTGGTCTCATCTTTCTGAAATACATCTCGGACACCTTTGAGG
CCAGGCACAAGTCCCTGCTGGCCGACAACCCTCAAGATGTCGAAGACCGGGACGCCTACCTCGCCGACAACGTATTCTGG
GTTCCGAAAGACGCGCGCTGGTCGCACCTGCAAGCCCATGCCAAGCAGCCCACCATCGGCACGCTGATCGACGACGCGAT
GCGCGCCATCGAAAAAGACAACGCAACGCTCCAGAGCGTGCTGCCCAAGGACTACGCCCGGCCAGCGCTCAACAAGGTGA
TGCTGGGCGAGTTGATCGACCTCATTTCCGGGATCACCCTCAACCAGGAAGGCCACGCCTCGCGCGACATTCTGGGGCGT
GTCTACGAATACTTCCTCGGCCAGTTCGCCGGCGCAGAAGGCAAGCGCGGCGGCGAGTTCTACACGCCCGGCTCCGTGGT
GCGCACCCTCGTCGAGATGCTGGAACCTTACCAAGGCCGCATCTATGACCCCTGCTGCGGCTCGGGCGGAATGTTCGTGC
AGTCCGAAAAATTCGTGCAAGAGCACGGCGGCCGCATCGGCGACATCGCCATCTACGGCCAGGAATCGAACCACGTCACC
TGGCGCCTGGCCAAGATGAACCTTGCGGTGCGCGGCATCGACTCCGACATCCGCTGGAACAACGAAGGCAGCTTTCACAA
GGACGAGTTGCGCGACCTCAAGGCCGACTACATCCTGGCCAACCCGCCATTCAATATTTCCGACTGGGGCGGCGACCGTC
TGCGGGAGGATGTGCGCTGGAAGTTCGGCGTGCCCCCGGTGGGCAACGCCAACTACGCGTGGCTGCAACACATCGTGCAC
CACCTGGCGCCGAATGGCACCGCAGGCGTGGTGCTGGCCAACGGCTCGATGTCATCCAGCCAGTCGGGCGAAGGCGACAT
CCGCCGCGAGATGGTCGAGCAAGACATCGTCGATTGCATGGTGGCGCTGCCGGGCCAGCTTTTTTACTCGACGCAAATCC
CGGCTTGCCTGTGGTTTCTGGCGCGCGACAAATCGAACGGGCGTGCGGGCAAAGCCTATCTGCGCGACCGGCGCAAAGAA
GTGCTGTTCATCGATGCACGCAAGCTCGGCGTGCTGGTGGATCGGACACGGCGTGAACTCACCGATGCCGATGTTCGACG
GATAGCAGGCACCTACCACGCATGGCGCGGTGAGCCGGGCGTGGGTGCGTATGCGGATGTGCCGGGCTTTTGCAAAGCGG
CAACACTGGACGACATCCGCAAACACGGGCATGTGCTGACGCCGGGGCGGTATGTGGGCGCCGAAGAAGTCGCCGACGAC
GGCACCCCTTTCGAGGAAAAAATGCAGATACTCACTGCCGAGTTGAACGCGCAGTTCGCCGAGTCTGCAAGGCTGGAGCA
GGCAATACGACTGAATCTGCAAGCCCTGGGGTACAAGCCATGA

Upstream 100 bases:

>100_bases
GCGTTTGATGGCTGTCGTCGGTATTTCGTAATCACTTCGGCCGCCGGAGCCGGGCCACGCCCCGGCCGCAAAGACAGAAC
GTAAACGAGGACAGAGCACG

Downstream 100 bases:

>100_bases
AAAACGCCAACACGCATTCGGGAGGCCGGCATGGCGGAGTTGAATTTTGACGCGTTGAAGTTATCCATTGCCGCCTTGGA
GCAAGGTTTGGAAGAACACG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MAQNDTNKKGSNLGFEAEMFKAADKLRGNMEPSDYKHVALGLIFLKYISDTFEARHKSLLADNPQDVEDRDAYLADNVFW
VPKDARWSHLQAHAKQPTIGTLIDDAMRAIEKDNATLQSVLPKDYARPALNKVMLGELIDLISGITLNQEGHASRDILGR
VYEYFLGQFAGAEGKRGGEFYTPGSVVRTLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNHVT
WRLAKMNLAVRGIDSDIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWKFGVPPVGNANYAWLQHIVH
HLAPNGTAGVVLANGSMSSSQSGEGDIRREMVEQDIVDCMVALPGQLFYSTQIPACLWFLARDKSNGRAGKAYLRDRRKE
VLFIDARKLGVLVDRTRRELTDADVRRIAGTYHAWRGEPGVGAYADVPGFCKAATLDDIRKHGHVLTPGRYVGAEEVADD
GTPFEEKMQILTAELNAQFAESARLEQAIRLNLQALGYKP

Sequences:

>Translated_520_residues
MAQNDTNKKGSNLGFEAEMFKAADKLRGNMEPSDYKHVALGLIFLKYISDTFEARHKSLLADNPQDVEDRDAYLADNVFW
VPKDARWSHLQAHAKQPTIGTLIDDAMRAIEKDNATLQSVLPKDYARPALNKVMLGELIDLISGITLNQEGHASRDILGR
VYEYFLGQFAGAEGKRGGEFYTPGSVVRTLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNHVT
WRLAKMNLAVRGIDSDIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWKFGVPPVGNANYAWLQHIVH
HLAPNGTAGVVLANGSMSSSQSGEGDIRREMVEQDIVDCMVALPGQLFYSTQIPACLWFLARDKSNGRAGKAYLRDRRKE
VLFIDARKLGVLVDRTRRELTDADVRRIAGTYHAWRGEPGVGAYADVPGFCKAATLDDIRKHGHVLTPGRYVGAEEVADD
GTPFEEKMQILTAELNAQFAESARLEQAIRLNLQALGYKP
>Mature_519_residues
AQNDTNKKGSNLGFEAEMFKAADKLRGNMEPSDYKHVALGLIFLKYISDTFEARHKSLLADNPQDVEDRDAYLADNVFWV
PKDARWSHLQAHAKQPTIGTLIDDAMRAIEKDNATLQSVLPKDYARPALNKVMLGELIDLISGITLNQEGHASRDILGRV
YEYFLGQFAGAEGKRGGEFYTPGSVVRTLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNHVTW
RLAKMNLAVRGIDSDIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWKFGVPPVGNANYAWLQHIVHH
LAPNGTAGVVLANGSMSSSQSGEGDIRREMVEQDIVDCMVALPGQLFYSTQIPACLWFLARDKSNGRAGKAYLRDRRKEV
LFIDARKLGVLVDRTRRELTDADVRRIAGTYHAWRGEPGVGAYADVPGFCKAATLDDIRKHGHVLTPGRYVGAEEVADDG
TPFEEKMQILTAELNAQFAESARLEQAIRLNLQALGYKP

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=386, Percent_Identity=23.8341968911917, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58016; Mature: 57885

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNDTNKKGSNLGFEAEMFKAADKLRGNMEPSDYKHVALGLIFLKYISDTFEARHKSLL
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADNPQDVEDRDAYLADNVFWVPKDARWSHLQAHAKQPTIGTLIDDAMRAIEKDNATLQSV
CCCCCCCCCCCCEEECCEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
LPKDYARPALNKVMLGELIDLISGITLNQEGHASRDILGRVYEYFLGQFAGAEGKRGGEF
CCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
YTPGSVVRTLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNHVT
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECHHHHHHHHCCCEEEEEEEECCCCCEE
WRLAKMNLAVRGIDSDIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRW
EEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHCCE
KFGVPPVGNANYAWLQHIVHHLAPNGTAGVVLANGSMSSSQSGEGDIRREMVEQDIVDCM
EECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
VALPGQLFYSTQIPACLWFLARDKSNGRAGKAYLRDRRKEVLFIDARKLGVLVDRTRREL
HHCCCHHEECCCHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHH
TDADVRRIAGTYHAWRGEPGVGAYADVPGFCKAATLDDIRKHGHVLTPGRYVGAEEVADD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHCCCEECCCCCCCHHHHCCC
GTPFEEKMQILTAELNAQFAESARLEQAIRLNLQALGYKP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQNDTNKKGSNLGFEAEMFKAADKLRGNMEPSDYKHVALGLIFLKYISDTFEARHKSLL
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADNPQDVEDRDAYLADNVFWVPKDARWSHLQAHAKQPTIGTLIDDAMRAIEKDNATLQSV
CCCCCCCCCCCCEEECCEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
LPKDYARPALNKVMLGELIDLISGITLNQEGHASRDILGRVYEYFLGQFAGAEGKRGGEF
CCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
YTPGSVVRTLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNHVT
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECHHHHHHHHCCCEEEEEEEECCCCCEE
WRLAKMNLAVRGIDSDIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRW
EEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHCCE
KFGVPPVGNANYAWLQHIVHHLAPNGTAGVVLANGSMSSSQSGEGDIRREMVEQDIVDCM
EECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
VALPGQLFYSTQIPACLWFLARDKSNGRAGKAYLRDRRKEVLFIDARKLGVLVDRTRREL
HHCCCHHEECCCHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHH
TDADVRRIAGTYHAWRGEPGVGAYADVPGFCKAATLDDIRKHGHVLTPGRYVGAEEVADD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHCCCEECCCCCCCHHHHCCC
GTPFEEKMQILTAELNAQFAESARLEQAIRLNLQALGYKP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]