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The map label for this gene is czrA [H]

Identifier: 121639658

GI number: 121639658

Start: 4167842

End: 4168204

Strand: Direct

Name: czrA [H]

Synonym: BCG_3803

Alternate gene names: 121639658

Gene position: 4167842-4168204 (Clockwise)

Preceding gene: 121639653

Following gene: 121639661

Centisome position: 95.28

GC content: 63.64

Gene sequence:

>363_bases
ATGGGGCACGGGGTCGAAGGCAGGAATCGTCCGTCAGCGCCGTTGGATTCCCAGGCCGCCGCGCAGGTCGCGTCCACACT
GCAGGCGTTGGCGACTCCGAGCCGGCTGATGATCCTCACCCAGCTACGGAACGGCCCGCTTCCGGTAACCGACCTCGCCG
AGGCTATTGGAATGGAACAGTCCGCCGTCTCGCATCAACTTCGAGTGTTGCGGAATCTCGGCTTGGTCGTGGGCGACCGG
GCAGGCCGTAGCATCGTCTACAGCCTCTACGACACGCATGTGGCGCAGCTTCTTGACGAAGCTATTTACCACAGCGAGCA
CTTGCACCTTGGTCTCTCCGACCGGCACCCCAGCGCGGGCTAA

Upstream 100 bases:

>100_bases
TGCACCGGGCGGGAGAGAGTTCACGAACAGCCACCCGGCCAACATATCAGAATATATGATCATATGTTCATTTATTTCTT
TGGGGATAGGCTGCCTAACC

Downstream 100 bases:

>100_bases
GCGGTCAGGCTCATAAGCTCGCGGGTCACTTTCACCCATGACCGGCGAGCTTTACAGACCCCAGCGCCTCAAGGGGCACC
ACCTCAAGGGCGCAGCCACC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MGHGVEGRNRPSAPLDSQAAAQVASTLQALATPSRLMILTQLRNGPLPVTDLAEAIGMEQSAVSHQLRVLRNLGLVVGDR
AGRSIVYSLYDTHVAQLLDEAIYHSEHLHLGLSDRHPSAG

Sequences:

>Translated_120_residues
MGHGVEGRNRPSAPLDSQAAAQVASTLQALATPSRLMILTQLRNGPLPVTDLAEAIGMEQSAVSHQLRVLRNLGLVVGDR
AGRSIVYSLYDTHVAQLLDEAIYHSEHLHLGLSDRHPSAG
>Mature_119_residues
GHGVEGRNRPSAPLDSQAAAQVASTLQALATPSRLMILTQLRNGPLPVTDLAEAIGMEQSAVSHQLRVLRNLGLVVGDRA
GRSIVYSLYDTHVAQLLDEAIYHSEHLHLGLSDRHPSAG

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12836; Mature: 12705

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHGVEGRNRPSAPLDSQAAAQVASTLQALATPSRLMILTQLRNGPLPVTDLAEAIGMEQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCH
SAVSHQLRVLRNLGLVVGDRAGRSIVYSLYDTHVAQLLDEAIYHSEHLHLGLSDRHPSAG
HHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
>Mature Secondary Structure 
GHGVEGRNRPSAPLDSQAAAQVASTLQALATPSRLMILTQLRNGPLPVTDLAEAIGMEQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCH
SAVSHQLRVLRNLGLVVGDRAGRSIVYSLYDTHVAQLLDEAIYHSEHLHLGLSDRHPSAG
HHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]