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The map label for this gene is virS [H]

Identifier: 121639652

GI number: 121639652

Start: 4160202

End: 4161263

Strand: Direct

Name: virS [H]

Synonym: BCG_3796

Alternate gene names: 121639652

Gene position: 4160202-4161263 (Clockwise)

Preceding gene: 121639651

Following gene: 121639653

Centisome position: 95.1

GC content: 63.94

Gene sequence:

>1062_bases
ATGTCCGTGGTGCGCGGGACCGCTCTGGCTAACTACCCGAGCCTGGTTGCCGGGTTGGGCGGTGACCCGGCCACTCTGCT
ACGGGCCGCGGGTGTTCGGGATCAGGATGTCGGCAACTATGACGCGTTCATTTCGATCCGGGCAGCGATTCGGGCAATCG
AATCGGCCGCAGCGGTCACCGCCACAATGGATTTCGGGAGACGATTGGCACAGCGGCAAGGGATTAAGATCCTGGGACCG
GTCGGTGTGGCGGCCCGCACGGCCGCCACGGTCGGTGACGCTCTGGCGATCTTCAACACCTTCATGGCGGCCTACAGCCC
AGTTATCGCCATCCGGATCACGCCGCTGGCCGGACAGCGGTCATTTATTGCACTCGAGTTCCTGCTCGACGAGCCGGCGT
CGTATCCGCAGACCATGGAGCTGGCGCTCGGGGTGGCGCTCGGGGTGATCCGGTTGTTGTTGGGCGCTGACTACGCCCCA
CTGGCCGTGCACTTACCCCACGACCCACTCACACCCGAAGCCTTCTACCTGCAGTACTTCGGCTGCCGGCCTTACTTCGC
CGAACGTGTTGGTGGTTTCACCATGCGCACCGCGGACCTGAGCCGTCCCCTCAACCGCGACGATGTCGCCCACCGGGTGG
TCGTCGACTACCTGAGCAGCATCACGCCGCTGGGCGAGGGGATCGTGGAATCGGTGCGCACCATCGTGCGCCAGCTGCTG
CCCACCGGAGCGGCGACGCTCAACGTGGTCGCCGAGCAGTTCCACCTGCACCCGAAAACGCTGCAACGTCGACTTGCGGA
GGAGAACACCACATTCGTTATTCTGGTCGATCGGGTCCGCAAGGATGTCGCCGATCGCTACCTAAGGACCACCGGGATCG
GCCTTACCCATTTGGCACGTGAACTGGGCTACGCCGAACAAAGCGTGTTGACCCGCTCGTGCAAACGCTGGTTCGGAACC
GGACCGGCCGCCTACCGCAACCAGGCCAGGTTACAGACAACCGTGAGCGCACCTGGCAGCGGGCGTGGTCCGAATCCAGG
TAACGTCTCAGTATCCTGCTGA

Upstream 100 bases:

>100_bases
CGCAGCGGCGTGACCTGTTGCGCGCCATCGGTTACAAGCTCTGATACGGGCCGCCGGTCCGCCCTTGACAGCGGGACGTC
CGCCGCAGAGGGTCGACGGC

Downstream 100 bases:

>100_bases
CCGATGGATCAAGATCGATCGGACAACACGGCATTGCGCCGTGGTCTGCGAATTGCCCTGCGCGGGCGCCGCGATCCGCT
GCCCGTGGCGGGCCGGCGGA

Product: AraC/XylS family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVTATMDFGRRLAQRQGIKILGP
VGVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQRSFIALEFLLDEPASYPQTMELALGVALGVIRLLLGADYAP
LAVHLPHDPLTPEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNRDDVAHRVVVDYLSSITPLGEGIVESVRTIVRQLL
PTGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVRKDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGT
GPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC

Sequences:

>Translated_353_residues
MSVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVTATMDFGRRLAQRQGIKILGP
VGVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQRSFIALEFLLDEPASYPQTMELALGVALGVIRLLLGADYAP
LAVHLPHDPLTPEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNRDDVAHRVVVDYLSSITPLGEGIVESVRTIVRQLL
PTGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVRKDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGT
GPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC
>Mature_352_residues
SVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVTATMDFGRRLAQRQGIKILGPV
GVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQRSFIALEFLLDEPASYPQTMELALGVALGVIRLLLGADYAPL
AVHLPHDPLTPEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNRDDVAHRVVVDYLSSITPLGEGIVESVRTIVRQLLP
TGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVRKDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGTG
PAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37973; Mature: 37842

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVT
CCCCCCCHHHCCHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATMDFGRRLAQRQGIKILGPVGVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQR
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCC
SFIALEFLLDEPASYPQTMELALGVALGVIRLLLGADYAPLAVHLPHDPLTPEAFYLQYF
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHC
GCRPYFAERVGGFTMRTADLSRPLNRDDVAHRVVVDYLSSITPLGEGIVESVRTIVRQLL
CCCHHHHHHHCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PTGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVRKDVADRYLRTTGIGLTHLAR
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHH
ELGYAEQSVLTRSCKRWFGTGPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC
HHCHHHHHHHHHHHHHHHCCCCHHHCCCHHEEEEECCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
SVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVT
CCCCCCHHHCCHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATMDFGRRLAQRQGIKILGPVGVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQR
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCC
SFIALEFLLDEPASYPQTMELALGVALGVIRLLLGADYAPLAVHLPHDPLTPEAFYLQYF
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHC
GCRPYFAERVGGFTMRTADLSRPLNRDDVAHRVVVDYLSSITPLGEGIVESVRTIVRQLL
CCCHHHHHHHCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PTGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVRKDVADRYLRTTGIGLTHLAR
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHH
ELGYAEQSVLTRSCKRWFGTGPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC
HHCHHHHHHHHHHHHHHHCCCCHHHCCCHHEEEEECCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]