| Definition | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome. |
|---|---|
| Accession | NC_008769 |
| Length | 4,374,522 |
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The map label for this gene is dfrA [H]
Identifier: 121639641
GI number: 121639641
Start: 4143781
End: 4144782
Strand: Direct
Name: dfrA [H]
Synonym: BCG_3785
Alternate gene names: 121639641
Gene position: 4143781-4144782 (Clockwise)
Preceding gene: 121639640
Following gene: 121639642
Centisome position: 94.73
GC content: 64.27
Gene sequence:
>1002_bases ATGCAGAATGCCACCATGCGCGTTCTGGTCACCGGCGGTACGGGATTTGTGGGCGGGTGGACTGCCAAAGCCATCGCTGA CGCGGGCCACTCCGTCCGGTTCCTGGTGCGAAATCCCGCACGGCTGAAGACGTCTGTCGCGAAACTGGGCGTCGACGTGT CGGACTTTGCGGTTGCAGACATATCCGACCGCGATTCGGTACGGGAGGCGTTGAACGGATGCGACGCCGTCGTGCACAGC GCCGCGCTGGTGGCAACCGACCCGCGTGAGACTTCGCGGATGCTGAGTACGAACATGGCGGGCGCCCAAAATGTTCTCGG TCAAGCCGTCGAGCTCGGAATGGATCCGATCGTGCATGTGTCGAGCTTCACGGCGCTGTTTCGTCCCAACTTGGCGACGC TGAGCGCTGATCTGCCGGTTGCCGGTGGGACGGATGGATACGGACAATCCAAAGCGCAGATCGAAATCTATGCGCGCGGT CTTCAGGACGCCGGCGCACCGGTGAACATCACTTATCCTGGCATGGTCCTCGGCCCGCCGGTGGGCGATCAATTCGGTGA AGCCGGGGAGGGTGTCCGGTCCGCATTGTGGATGCATGTCATTCCCGGGCGCGGCGCGGCGTGGTTGATCGTCGACGTCC GAGATGTGGCGGCACTGCACGCGGCGTTGTTGGAATCCGGGCGTGGGCCGCGCCGCTACACTGCGGGAGGTCATCGGATT CCGGTGCCCGAGCTCGCGAAAATTCTGGGCGAGGTCGCCGGCACCACGATGCTGGCCGTCCCGGTGCCCGATTCCGCGCT GCGTGTCGCGGGATCGGTGCTGGATCAAGCCGGGCCCTATCTGCCTTTCAATACTCCGTTCACCGCGGCAGGTATGCAGT ACTACACACAGATGCCGGAGCCCGACGATTCGCCGAGCGAAAAAGAACTAGGCATCACCTACCGCGATCCGCGCGACACC GTGGCCGACACCGTCACGGCCCTGCGCGGCCTGGGCAGCTAA
Upstream 100 bases:
>100_bases ACGCGGTGAACGGCATGGTAGGCCAGGGCGCGAATTTCGCCGCCAGCCGCCTGTAGCCAGAACTGCGCTGCCACCCCAGC GAGAGCTGGGCGGTGATCCA
Downstream 100 bases:
>100_bases CTGCCGTCGGGAGGTTCCGCCGGTTCCGCGTCGGGGCGCGAATTCTTCAACCACTGCTTCAGCCGGAGCAGTTCGTTGAC GACGATGCCGACGCCCAGGA
Product: putative oxidoreductase
Products: NA
Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]
Number of amino acids: Translated: 333; Mature: 333
Protein sequence:
>333_residues MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLGVDVSDFAVADISDRDSVREALNGCDAVVHS AALVATDPRETSRMLSTNMAGAQNVLGQAVELGMDPIVHVSSFTALFRPNLATLSADLPVAGGTDGYGQSKAQIEIYARG LQDAGAPVNITYPGMVLGPPVGDQFGEAGEGVRSALWMHVIPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRI PVPELAKILGEVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPEPDDSPSEKELGITYRDPRDT VADTVTALRGLGS
Sequences:
>Translated_333_residues MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLGVDVSDFAVADISDRDSVREALNGCDAVVHS AALVATDPRETSRMLSTNMAGAQNVLGQAVELGMDPIVHVSSFTALFRPNLATLSADLPVAGGTDGYGQSKAQIEIYARG LQDAGAPVNITYPGMVLGPPVGDQFGEAGEGVRSALWMHVIPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRI PVPELAKILGEVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPEPDDSPSEKELGITYRDPRDT VADTVTALRGLGS >Mature_333_residues MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLGVDVSDFAVADISDRDSVREALNGCDAVVHS AALVATDPRETSRMLSTNMAGAQNVLGQAVELGMDPIVHVSSFTALFRPNLATLSADLPVAGGTDGYGQSKAQIEIYARG LQDAGAPVNITYPGMVLGPPVGDQFGEAGEGVRSALWMHVIPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRI PVPELAKILGEVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPEPDDSPSEKELGITYRDPRDT VADTVTALRGLGS
Specific function: Galactose metabolism; third step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the dihydroflavonol-4-reductase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001509 - InterPro: IPR017829 - InterPro: IPR016040 [H]
Pfam domain/function: PF01370 Epimerase [H]
EC number: =1.1.1.219 [H]
Molecular weight: Translated: 34773; Mature: 34773
Theoretical pI: Translated: 5.35; Mature: 5.35
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLGVDVSDFAVAD CCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHEEEEC ISDRDSVREALNGCDAVVHSAALVATDPRETSRMLSTNMAGAQNVLGQAVELGMDPIVHV CCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH SSFTALFRPNLATLSADLPVAGGTDGYGQSKAQIEIYARGLQDAGAPVNITYPGMVLGPP HHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEECHHCCCCCEEEECCCEEECCC VGDQFGEAGEGVRSALWMHVIPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRI CCCHHCHHHHHHHHHHEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCC PVPELAKILGEVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPE CHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC PDDSPSEKELGITYRDPRDTVADTVTALRGLGS CCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCC >Mature Secondary Structure MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLGVDVSDFAVAD CCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHEEEEC ISDRDSVREALNGCDAVVHSAALVATDPRETSRMLSTNMAGAQNVLGQAVELGMDPIVHV CCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH SSFTALFRPNLATLSADLPVAGGTDGYGQSKAQIEIYARGLQDAGAPVNITYPGMVLGPP HHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEECHHCCCCCEEEECCCEEECCC VGDQFGEAGEGVRSALWMHVIPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRI CCCHHCHHHHHHHHHHEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCC PVPELAKILGEVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPE CHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC PDDSPSEKELGITYRDPRDTVADTVTALRGLGS CCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]