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The map label for this gene is aspB [C]

Identifier: 121639484

GI number: 121639484

Start: 3985092

End: 3986258

Strand: Direct

Name: aspB [C]

Synonym: BCG_3629

Alternate gene names: 121639484

Gene position: 3985092-3986258 (Clockwise)

Preceding gene: 121639483

Following gene: 121639491

Centisome position: 91.1

GC content: 66.5

Gene sequence:

>1167_bases
GTGACGGATCGTGTCGCCCTGCGTGCCGGCGTTCCCCCGTTCTACGTGATGGACGTCTGGTTGGCGGCCGCGGAGCGCCA
GCGCACCCATGGGGATCTGGTGAATCTTTCGGCGGGCCAACCCAGTGCGGGCGCTCCGGAACCGGTGCGTGCGGCCGCGG
CCGCCGCCCTGCATCTCAACCAGTTGGGATACTCGGTGGCGCTGGGTATTCCGGAGCTGCGCGACGCTATCGCCGCGGAT
TACCAACGCCGGCATGGCATCACCGTCGAACCCGATGCGGTGGTGATCACCACGGGCTCCTCGGGCGGCTTTCTGCTCGC
GTTTCTGGCGTGCTTCGACGCCGGTGATCGGGTCGCGATGGCCAGTCCCGGCTACCCGTGCTACCGGAATATCCTGTCAG
CGCTGGGATGTGAGGTCGTGGAGATCCCGTGCGGACCGCAGACCCGATTCCAACCGACCGCGCAGATGCTGGCCGAGATC
GACCCACCGCTGCGCGGTGTCGTCGTCGCCAGCCCGGCCAACCCGACCGGAACCGTCATCCCGCCCGAAGAACTGGCGGC
CATCGCGTCGTGGTGTGACGCATCGGATGTCCGGTTGATCAGTGATGAGGTCTACCACGGCCTGGTGTACCAGGGGGCAC
CGCAAACCAGCTGCGCCTGGCAGACGTCGCGAAACGCGGTGGTAGTCAACAGCTTTTCCAAGTATTACGCGATGACGGGC
TGGCGGCTGGGCTGGCTGCTGGTGCCGACGGTGCTGCGCCGCGCGGTGGACTGCCTGACCGGCAACTTCACCATCTGCCC
GCCGGTCTTGTCGCAGATCGCCGCGGTGTCCGCGTTCACCCCGGAGGCGACCGCCGAGGCCGACGGCAACCTGGCCAGCT
ACGCGATCAACCGCTCGCTGTTGCTGGACGGTCTGCGTCGCATCGGCATCGACCGGCTGGCACCCACCGACGGCGCATTC
TACGTCTACGCCGACGTCTCGGACTTCACCAGCGATTCGCTGGCCTTCTGCTCAAAGTTGCTGGCCGACACCGGTGTTGC
GATCGCACCCGGAATCGATTTCGACACCGCACGGGGGGGTTCGTTTGTTCGGATATCGTTTGCCGGGCCAAGCGGCGACA
TCGAAGAAGCCTTACGGCGCATCGGCTCCTGGCTGCCGAGCCAATAG

Upstream 100 bases:

>100_bases
ACATGCACCTGTATTTCAAACGAGCGCACGGCAGTGCACAATTGCTCGAGTCGCCACGAGAGGTGCTGCGCCGTTTGGAA
TCTGAGGTGTGGGAGTCGCC

Downstream 100 bases:

>100_bases
CTCGTCGATGCGCGTCTCGAGCGCGCCGCGCTCGCCGATATCTGCCACGTTGATCCCGAACCGTTCGCTCAGGGTGTCGA
CAACCGCTGCCGCATCGGCA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAAD
YQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEI
DPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTG
WRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAF
YVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ

Sequences:

>Translated_388_residues
MTDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAAD
YQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEI
DPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTG
WRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAF
YVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ
>Mature_387_residues
TDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAADY
QRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEID
PPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTGW
RLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFY
VYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=410, Percent_Identity=25.1219512195122, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI169881279, Length=410, Percent_Identity=25.1219512195122, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=25.1908396946565, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=25.1908396946565, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI169881281, Length=249, Percent_Identity=24.8995983935743, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI19263340, Length=378, Percent_Identity=23.015873015873, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI215599424, Length=378, Percent_Identity=23.015873015873, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4507369, Length=371, Percent_Identity=22.6415094339623, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4885351, Length=353, Percent_Identity=25.2124645892351, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=28.0104712041885, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=26.8698060941828, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1790797, Length=236, Percent_Identity=31.3559322033898, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788627, Length=270, Percent_Identity=27.037037037037, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787710, Length=335, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=26.2162162162162, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=397, Percent_Identity=25.1889168765743, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=397, Percent_Identity=25.1889168765743, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=312, Percent_Identity=25, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534666, Length=350, Percent_Identity=24.5714285714286, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=230, Percent_Identity=28.2608695652174, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI18859735, Length=372, Percent_Identity=25, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=23.7244897959184, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=23.7244897959184, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=23.7244897959184, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=23.7244897959184, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41081; Mature: 40950

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLN
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
QLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAM
HCCCEEEECCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCHHHHHHHHHCCCCEEEE
ASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVI
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCC
PPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTG
CHHHHHHHHHHCCCCCCEEHHHHHHHCEEECCCCCCCCCEECCCCEEEEECCHHHHHHCC
WRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSL
CHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGG
HHHHHHHHCCHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SFVRISFAGPSGDIEEALRRIGSWLPSQ
CEEEEEECCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLN
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
QLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAM
HCCCEEEECCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCHHHHHHHHHCCCCEEEE
ASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVI
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCC
PPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTG
CHHHHHHHHHHCCCCCCEEHHHHHHHCEEECCCCCCCCCEECCCCEEEEECCHHHHHHCC
WRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSL
CHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGG
HHHHHHHHCCHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SFVRISFAGPSGDIEEALRRIGSWLPSQ
CEEEEEECCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]