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The map label for this gene is 121639471

Identifier: 121639471

GI number: 121639471

Start: 3969663

End: 3970415

Strand: Direct

Name: 121639471

Synonym: BCG_3616

Alternate gene names: NA

Gene position: 3969663-3970415 (Clockwise)

Preceding gene: 121639470

Following gene: 121639472

Centisome position: 90.75

GC content: 66.0

Gene sequence:

>753_bases
GTGAGCACCCGAGCCGAAGTGTGTGCCGTCGCCTGCGCCGAGTTGTTCCGCGATGCAGGCGAAATCATGATCAGCCCCAT
GACCAACATGGCCTCGGTAGGGGCGCGGCTGGCGCGGCTCACCTTCGCGCCGGACATTCTGCTGACCGACGGCGAGGCTC
AGCTGCTCGCGGACACACCGGCATTGGGCAAGACGGGCGCCCCAAACAGGATTGAGGGGTGGATGCCGTTCGGCCGGGTT
TTCGAAACCCTGGCCTGGGGGCGCCGGCACGTGGTGATGGGCGCCAATCAGGTCGACCGCTATGGCAATCAGAACATCTC
GGCGTTCGGGCCGCTGCAGCGGCCGACCCGGCAGATGTTCGGCGTCCGCGGCTCGCCGGGCAACACCATCAACCACGCCA
CCAGTTACTGGGTGGGCAACCACTGCAAGCGGGTCTTTGTCGAGGCCGTCGATGTGGTCTCCGGCATCGGCTACGACAAG
GTGGATCCGGACAATCCGGCCTTCCGGTTCGTCAACGTCTACCGGGTGGTGTCCAACCTAGGCGTGTTCGACTTCGGCGG
CCCCGACCACTCCATGCGGGCGGTATCCCTACACCCCGGGGTGACGCCCGGCGACGTCCGCGACGCCACCTCGTTCGAGG
TGCATGACCTCGACGCGGCCGAGCAGACCAGGCTGCCCACCGACGACGAACTGCACCTGATCCGCGCGGTAATCGATCCG
AAGTCGTTGCGGGACAGGGAGATACGATCATGA

Upstream 100 bases:

>100_bases
CGGCGTCGACACAGGTGGGTTGGCAGCAGTTCGTGCACACCTACCTATCCGGCACCGAAGCGGACTACCAGGCCGCGGTG
CACAACTTTGGAGCATCACG

Downstream 100 bases:

>100_bases
TTGTTCCGCCTCCTCTCCCCCGCAAGCGGGAGGTGCGCCCACATCGCTTCGTCCCCTGCAAGCGGGTGGTACCCCCACTG
CATTGTCGGCGGTGGCTATG

Product: putative CoA-transferase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRV
FETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDK
VDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDP
KSLRDREIRS

Sequences:

>Translated_250_residues
MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRV
FETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDK
VDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDP
KSLRDREIRS
>Mature_249_residues
STRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVF
ETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKV
DPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDPK
SLRDREIRS

Specific function: Probable subunit of a CoA-transferase composed of Rv3551 and Rv3552

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3552_MYCTU (P63652)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   A70678
- RefSeq:   NP_218069.1
- RefSeq:   NP_338202.1
- ProteinModelPortal:   P63652
- SMR:   P63652
- EnsemblBacteria:   EBMYCT00000002987
- EnsemblBacteria:   EBMYCT00000070575
- GeneID:   887453
- GeneID:   926555
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3656
- KEGG:   mtu:Rv3552
- TIGR:   MT3656
- TubercuList:   Rv3552
- GeneTree:   EBGT00050000017554
- HOGENOM:   HBG353770
- OMA:   FGQANIS
- ProtClustDB:   CLSK872198

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27393; Mature: 27262

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTP
CCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCC
ALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMF
CCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCCCCCCHHHHHHC
GVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDP
CCEECCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCHHHCCCCCCCHHHHHHHHHCC
KSLRDREIRS
HHHCCCCCCC
>Mature Secondary Structure 
STRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTP
CCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCC
ALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMF
CCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCCCCCCHHHHHHC
GVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDP
CCEECCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCHHHCCCCCCCHHHHHHHHHCC
KSLRDREIRS
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036