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The map label for this gene is atoD [C]

Identifier: 121639470

GI number: 121639470

Start: 3968788

End: 3969666

Strand: Direct

Name: atoD [C]

Synonym: BCG_3615

Alternate gene names: 121639470

Gene position: 3968788-3969666 (Clockwise)

Preceding gene: 121639469

Following gene: 121639471

Centisome position: 90.73

GC content: 67.24

Gene sequence:

>879_bases
GTGCCCGATAAACGAACCTCTCTTGACGACGCCGTCGCGCAATTGCGCAGCGGCATGACCATCGGCATCGCCGGCTGGGG
CTCGCGGCGCAAGCCCATGGCGTTCGTGCGGGCCATCCTGCGCTCGGATGTCACCGATTTGACGGTGGTCACCTACGGCG
GGCCGGACCTGGGGCTGCTGTGCTCGGCGGGCAAGGTCAAGCGGGTCTACTACGGGTTCGTCTCGCTGGACTCGCCGCCG
TTCTACGACCCGTGGTTCGCGCACGCCCGCACCAGCGGCGCGATCGAGGCCCGGGAGATGGACGAGGGCATGCTGCGCTG
CGGTTTGCAGGCCGCGGCACAACGGCTGCCGTTCCTGCCTATTCGCGCCGGGCTGGGCAGCTCGGTACCACAGTTCTGGG
CAGGCGAGCTGCAGACGGTCACGTCGCCGTATCCGGCGCCTGGCGGCGGGTACGAGACACTGATCGCCATGCCGGCACTG
CGCCTGGATGCCGCCTTCGCCCACTTGAATCTCGGTGACAGCCACGGCAATGCGGCCTACACCGGCATCGACCCCTACTT
CGACGATCTCTTCTTGATGGCCGCCGAGCGGCGCTTTCTGTCGGTGGAGCGCATCGTCGCCACCGAGGAACTGGTCAAAT
CGGTGCCGCCGCAGGCGCTGTTGGTCAACCGGATGATGGTCGACGCCATCGTGGAAGCACCCGGCGGCGCCCACTTCACC
ACCGCCGCACCGGACTACGGGCGCGACGAGCAGTTCCAGCGGCACTACGCCGAAGCGGCGTCGACACAGGTGGGTTGGCA
GCAGTTCGTGCACACCTACCTATCCGGCACCGAAGCGGACTACCAGGCCGCGGTGCACAACTTTGGAGCATCACGGTGA

Upstream 100 bases:

>100_bases
GGGTCAATGCGAGTTACCGGATGGAGCAAGGTTTTACCTTCGAGCTCAACCTCGCCGGAGTCGCCGACGAGCACCGCGAC
GCCTTTGTGAAGAAGTCATA

Downstream 100 bases:

>100_bases
GCACCCGAGCCGAAGTGTGTGCCGTCGCCTGCGCCGAGTTGTTCCGCGATGCAGGCGAAATCATGATCAGCCCCATGACC
AACATGGCCTCGGTAGGGGC

Product: putative CoA-transferase subunit alpha

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPDKRTSLDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPP
FYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPAL
RLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFT
TAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR

Sequences:

>Translated_292_residues
MPDKRTSLDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPP
FYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPAL
RLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFT
TAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
>Mature_291_residues
PDKRTSLDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPPF
YDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALR
LDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFTT
AAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR

Specific function: Probable subunit of a CoA-transferase composed of Rv3551 and Rv3552 [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 31739; Mature: 31608

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKRTSLDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLL
CCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEE
CSAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLP
ECCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEE
IRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDSHGNAAY
ECCCCCCCCHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCEEE
TGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEE
TAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDKRTSLDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLL
CCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEE
CSAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLP
ECCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEE
IRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDSHGNAAY
ECCCCCCCCHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCEEE
TGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEE
TAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]