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The map label for this gene is fadE27 [H]

Identifier: 121639424

GI number: 121639424

Start: 3903195

End: 3904316

Strand: Direct

Name: fadE27 [H]

Synonym: BCG_3569

Alternate gene names: 121639424

Gene position: 3903195-3904316 (Clockwise)

Preceding gene: 121639423

Following gene: 121639425

Centisome position: 89.23

GC content: 68.27

Gene sequence:

>1122_bases
ATGGATTTCACGACAACCGAAGCCGCCCAGGATCTTGGTGGTCTGGTCGACACCATCGTGGACGCGGTGTGCACGCCGGA
GCATCAACGTGAGCTGGACAAGCTCGAGCAGCGGTTCGACCGCGAGCTGTGGCGCAAGCTGATAGACGCCGGCATCCTGT
CCAGTGCGGCGCCGGAGTCGCTGGGCGGCGATGGCTTCGGCGTGCTCGAGCAGGTTGCGGTGCTGGTGGCGTTGGGGCAT
CAACTGGCCGCGGTGCCGTACCTGGAGTCGGTGGTGCTCGCCGCCGGCGCCCTGGCCCGGTTCGGCTCGCCGGAACTGCA
GCAGGGCTGGGGGGTGTCGGCGGTCTCCGGCGATCGGATCCTCACCGTCGCCCTCGACGGTGAGATGGGCGAGGGTCCGG
TGCAGGCCGCCGGCACCGGACATGGCTACCGCCTCACCGGCACACGCACCCAGGTCGGGTACGGCCCGGTGGCCGACGCA
TTTCTGGTACCCGCCGAAACCGATTCCGGTGCAGCCGTTTTCCTGGTTGCCGCCGGCGACCCAGGGGTTGCGGTGACCGC
ACTGGCCACCACCGGACTGGGCAGCGTCGGACACCTCGAGCTAAACGGGGCCAAAGTGGACGCCGCCCGCAGGGTCGGCG
GAACCGATGTCGTGGTTTGGCTCGGCACGCTTTCCACCCTGAGCCGCACCGCTTTTCAGCTCGGTGTGCTCGAGCGCGGA
CTGCAAATGACGGCCGAATATGCGCGCACCCGTGAACAATTCGACCGCCCGATCGGCAGCTTCCAGGCGGTGGGGCAACG
GTTGGCTGACGGCTACATCGACGTCAAGGGATTGCGACTGACGCTTACCCAGGCGGCCTGGCGGGTGGCCGAAGATTCCC
TGGCAAGCCGGGAGTGCCCCCAGCCAGCCGACATCGACGTCGCCACCGCGGGGTTCTGGGCCGCCGAAGCCGGGCATCGG
GTGGCGCATACCATCGTGCATGTGCATGGCGGCGTCGGCGTCGACACCGATCATCCCGTACACCGGTATTTCCTGGCCGC
CAAGCAGACCGAGTTCGCGTTGGGCGGCGCCACCGGTCAGCTCCGCCGAATCGGCCGTGAACTGGCGGAAACCCCTGCCT
AG

Upstream 100 bases:

>100_bases
CGGCGGCGGCACCAACGAAGTCCAGCGCGACATCATCGGCATGGTCGCGCTGGGACTGCCGCGAGCCAACCGCTGAGCGG
ACCTGAGAGGACAAGACGTC

Downstream 100 bases:

>100_bases
CCCTGCCTAGCCCGGCGACGATGCGGTCCGCGCAGCGGACCGAGAAGGAGCGGGCGAATCGAACCCACCGATGACTCCCA
CTCACCCGACCGTCACCGAA

Product: putative acyl-CoA dehydrogenase fadE27

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGH
QLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADA
FLVPAETDSGAAVFLVAAGDPGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVVVWLGTLSTLSRTAFQLGVLERG
LQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHR
VAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA

Sequences:

>Translated_373_residues
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGH
QLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADA
FLVPAETDSGAAVFLVAAGDPGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVVVWLGTLSTLSRTAFQLGVLERG
LQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHR
VAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA
>Mature_373_residues
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGH
QLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADA
FLVPAETDSGAAVFLVAAGDPGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVVVWLGTLSTLSRTAFQLGVLERG
LQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHR
VAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=361, Percent_Identity=27.4238227146814, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI226958414, Length=354, Percent_Identity=27.9661016949153, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557233, Length=387, Percent_Identity=25.0645994832041, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI87081958, Length=363, Percent_Identity=23.4159779614325, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=351, Percent_Identity=26.7806267806268, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355753, Length=366, Percent_Identity=26.775956284153, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356377, Length=382, Percent_Identity=24.6073298429319, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=25.1322751322751, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 39036; Mature: 39036

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPES
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEECCCEE
LTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGD
EEEEECCCCCCCCCEECCCCCCEEEECCCEECCCCCCCCCEEEECCCCCCCEEEEEECCC
PGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVVVWLGTLSTLSRTAFQLGVLERG
CCEEEEEEECCCCCCCCEEEECCCEEHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
LQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCEEEEHHHHHHHHHHHHHHHCCCC
QPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQ
CCCCCCEEECCHHHHHCCCHHEEHEEEEECCCCCCCCCCHHHHHHHHCCCCEEECCCHHH
LRRIGRELAETPA
HHHHHHHHHCCCC
>Mature Secondary Structure
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPES
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEECCCEE
LTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGD
EEEEECCCCCCCCCEECCCCCCEEEECCCEECCCCCCCCCEEEECCCCCCCEEEEEECCC
PGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVVVWLGTLSTLSRTAFQLGVLERG
CCEEEEEEECCCCCCCCEEEECCCEEHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
LQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCEEEEHHHHHHHHHHHHHHHCCCC
QPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQ
CCCCCCEEECCHHHHHCCCHHEEHEEEEECCCCCCCCCCHHHHHHHHCCCCEEECCCHHH
LRRIGRELAETPA
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]