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The map label for this gene is yafE [C]

Identifier: 121639270

GI number: 121639270

Start: 3719908

End: 3720639

Strand: Direct

Name: yafE [C]

Synonym: BCG_3412

Alternate gene names: 121639270

Gene position: 3719908-3720639 (Clockwise)

Preceding gene: 121639269

Following gene: 121639275

Centisome position: 85.04

GC content: 69.26

Gene sequence:

>732_bases
GTGACGTGCTCCCGACGCGACATGTCCCTGTCGTTTGGCTCCGCGGTCGGCGCCTACGAGCGCGGGCGCCCCTCGTATCC
ACCGGAAGCCATCGACTGGCTGCTGCCGGCCGCCGCCCGCCGCGTGCTCGACCTGGGAGCGGGCACCGGCAAGCTGACCA
CCCGGCTAGTCGAGCGCGGCCTGGACGTGGTTGCCGTCGACCCGATCCCGGAGATGCTGGACGTGCTGCGTGCTGCGCTG
CCGCAAACCGTCGCGCTGCTGGGCACCGCCGAAGAGATTCCGTTGGACGACAACAGCGTTGACGCGGTGTTGGTGGCTCA
GGCGTGGCACTGGGTGGATCCCGCCCGGGCGATTCCGGAGGTCGCCCGGGTGTTGCGTCCGGGCGGGCGGCTCGGCCTGG
TGTGGAACACCCGCGACGAACGGCTGGGCTGGGTGCGCGAGCTGGGTGAGATCATCGGTCGCGACGGCGATCCGGTGCGC
GACAGGGTGACGCTGCCCGAGCCGTTCACTACGGTGCAGCGCCATCAGGTCGAGTGGACGAATTACCTGACACCACAAGC
CCTTATCGACCTGGTGGCTTCGCGCAGCTATTGCATCACCTCACCGGCGCAGGTCCGCACCAAAACGCTCGACCGGGTGC
GGCAGTTGCTGGCCACCCATCCGGCGCTGGCGAATAGCAACGGCCTGGCGCTGCCCTACGTCACGGTCTGTGTGCGGGCG
ACTCTGGCCTGA

Upstream 100 bases:

>100_bases
CGGTCTACGGACACGACGGCTTCCTGGTGGAAACCGAGGCCGTGGGCGAATTGATCCGCCAGACACTGGGATTGGCTGAT
CGTGAAGGCGCGTGTCGGCG

Downstream 100 bases:

>100_bases
CGCCGCCTTTAGGGCCCGGTGCCGGTGTAAATCAGGCCCGCCAGTTGCTGGCCGACGTTGCCGAAGCCGGAGACCAGGGC
CGAGGTGATCAGGCCCAGCG

Product: putative methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAAL
PQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVR
DRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRA
TLA

Sequences:

>Translated_243_residues
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAAL
PQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVR
DRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRA
TLA
>Mature_242_residues
TCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALP
QTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRD
RVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRAT
LA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3342_MYCTU (P65348)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- PIR:   E70846
- RefSeq:   NP_217859.1
- RefSeq:   NP_337975.1
- ProteinModelPortal:   P65348
- SMR:   P65348
- EnsemblBacteria:   EBMYCT00000002798
- EnsemblBacteria:   EBMYCT00000070143
- GeneID:   888046
- GeneID:   926419
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3445
- KEGG:   mtu:Rv3342
- TIGR:   MT3445
- TubercuList:   Rv3342
- GeneTree:   EBGT00050000014592
- HOGENOM:   HBG322479
- OMA:   WVHRLSR
- ProtClustDB:   CLSK872170
- InterPro:   IPR013216

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 26641; Mature: 26510

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERG
CCCCCCCCCCCHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
LDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPE
CCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHH
VARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWT
HHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRA
HCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
TLA
HCC
>Mature Secondary Structure 
TCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERG
CCCCCCCCCCHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
LDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPE
CCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHH
VARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWT
HHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRA
HCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
TLA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036