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The map label for this gene is 121639083

Identifier: 121639083

GI number: 121639083

Start: 3523817

End: 3524071

Strand: Direct

Name: 121639083

Synonym: BCG_3223

Alternate gene names: NA

Gene position: 3523817-3524071 (Clockwise)

Preceding gene: 121639080

Following gene: 121639088

Centisome position: 80.55

GC content: 58.04

Gene sequence:

>255_bases
ATGATCACCGCTGCGCTCACCATCTATACGACATCATGGTGTGGCTATTGCCTTCGACTCAAAACAGCGCTCACGGCCAA
CCGAATCGCTTACGACGAGGTCGACATCGAACACAACCGTGCGGCCGCGGAGTTCGTCGGCTCGGTCAATGGCGGCAACA
GAACTGTTCCCACGGTGAAGTTCGCCGACGGGTCGACGCTGACTAACCCGAGCGCGGACGAGGTCAAAGCGAAGCTGGTA
AAGATCGCGGGTTAA

Upstream 100 bases:

>100_bases
ATGACAGACCGGGCGTGTCGCCACGCCGTGGGGCGTGCGACATGAACAACTGCCGAGCCGCCACACCGCCCGGGTCGTCG
CCGCGCTAGGTTAGCGTGTC

Downstream 100 bases:

>100_bases
CGACGTGGACTTTCATTCGCACGCTGCCCACGATTCGATGATCACGCGGGCGATCGAGATCGACCCGGGCAGTAGCAGTT
TCGACTCCGACGCACTGGAC

Product: putative glutaredoxin protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MITAALTIYTTSWCGYCLRLKTALTANRIAYDEVDIEHNRAAAEFVGSVNGGNRTVPTVKFADGSTLTNPSADEVKAKLV
KIAG

Sequences:

>Translated_84_residues
MITAALTIYTTSWCGYCLRLKTALTANRIAYDEVDIEHNRAAAEFVGSVNGGNRTVPTVKFADGSTLTNPSADEVKAKLV
KIAG
>Mature_84_residues
MITAALTIYTTSWCGYCLRLKTALTANRIAYDEVDIEHNRAAAEFVGSVNGGNRTVPTVKFADGSTLTNPSADEVKAKLV
KIAG

Specific function: Unknown

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3198_MYCTU (Q8VJ51)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- RefSeq:   NP_337821.1
- RefSeq:   YP_177941.1
- ProteinModelPortal:   Q8VJ51
- SMR:   Q8VJ51
- EnsemblBacteria:   EBMYCT00000000372
- EnsemblBacteria:   EBMYCT00000071530
- GeneID:   3205084
- GeneID:   923288
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3292
- KEGG:   mtu:Rv3198A
- TIGR:   MT3292
- TubercuList:   Rv3198A
- GeneTree:   EBGT00050000016305
- HOGENOM:   HBG728471
- OMA:   GNHVVPT
- ProtClustDB:   CLSK799967
- InterPro:   IPR011915
- InterPro:   IPR002109
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR02200

Pfam domain/function: PF00462 Glutaredoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 8963; Mature: 8963

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS51354 GLUTAREDOXIN_2; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAALTIYTTSWCGYCLRLKTALTANRIAYDEVDIEHNRAAAEFVGSVNGGNRTVPTVK
CCEEEEEEEECCHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHCCCCCCCCCCCEEE
FADGSTLTNPSADEVKAKLVKIAG
ECCCCCCCCCCHHHHHEEEEEECC
>Mature Secondary Structure
MITAALTIYTTSWCGYCLRLKTALTANRIAYDEVDIEHNRAAAEFVGSVNGGNRTVPTVK
CCEEEEEEEECCHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHCCCCCCCCCCCEEE
FADGSTLTNPSADEVKAKLVKIAG
ECCCCCCCCCCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036