Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 121639080

GI number: 121639080

Start: 3519506

End: 3520849

Strand: Direct

Name: ubiB [C]

Synonym: BCG_3220

Alternate gene names: 121639080

Gene position: 3519506-3520849 (Clockwise)

Preceding gene: 121639078

Following gene: 121639083

Centisome position: 80.45

GC content: 64.06

Gene sequence:

>1344_bases
ATGGATGATGGGAGTGTGTCAGATATCAAACGGGGCCGCGCCGCGCGCAATGCGAAGCTGGCCAGCATCCCGGTCGGCTT
CGCCGGTCGGGCGGCGCTCGGGCTCGGCAAGCGACTGACCGGTAAGTCAAAAGACGAGGTTACCGCCGAGCTGATGGAGA
AGGCCGCCAATCAGTTGTTTACCGTCCTCGGCGAACTCAAGGGTGGCGCGATGAAGGTCGGCCAGGCGCTGTCGGTGATG
GAGGCCGCCATTCCCGACGAGTTCGGCGAACCCTACCGGGAAGCACTGACCAAGCTGCAGAAGGACGCCCCACCGCTGCC
CGCCAGTAAGGTGCACCGGGTACTCGACGGACAGCTGGGCACCAAATGGCGGGAGCGGTTCAGCTCGTTCAACGACACCC
CAGTGGCATCTGCCAGCATCGGCCAGGTGCACAAAGCAATCTGGTCGGACGGCCGAGAAGTGGCCGTCAAGATCCAGTAT
CCCGGCGCCGACGAGGCGCTGCGCGCGGACCTCAAGACCATGCAGCGCATGGTCGGCGTGCTCAAACAGCTCTCACCCGG
CGCCGACGTCCAAGGGGTGGTCGACGAACTGGTTGAACGCACCGAAATGGAACTCGACTACCGGCTGGAGGCCGCCAACC
AGCGCGCCTTCGCCAAGGCGTACCACGACCACCCGCGCTTCCAGGTGCCTCACGTCGTGGCAAGCGCACCGAAGGTGGTG
ATCCAGGAGTGGATCGAAGGTGTGCCGATGGCAGAGATCATCCGTCACGGGACCACCGAGCAGCGTGATCTGATCGGTAC
GCTGCTCGCCGAGCTCACCTTCGACGCACCACGGCGGCTGGGGTTGATGCACGGCGACGCCCACCCCGGTAATTTCATGC
TGCTGCCCGACGGCCGGATGGGCATCATCGACTTCGGTGCCGTGGCACCGATGCCCGGCGGCTTCCCGATAGAGCTCGGG
ATGACGATTCGACTGGCCCGAGAGAAGAACTACGACCTCCTGTTGCCGACGATGGAGAAGGCCGGGTTGATCCAGCGAGG
ACGACAGGTGTCGGTTCGCGAGATCGACGAGATGCTGCGCCAATACGTCGAGCCCATCCAGGTCGAGGTCTTCCACTACA
CCCGCAAGTGGTTACAGAAAATGACCGTCAGTCAGATCGACCGCTCGGTTGCGCAGATCAGAACGGCGCGCCAGATGGAC
CTGCCGGCCAAGCTCGCGATTCCGATGCGGGTTATCGCATCGGTGGGCGCGATCCTATGCCAGCTGGACGCGCATGTGCC
GATCAAGGCCCTGTCGGAGGAGCTGATCCCGGGTTTCGCCGAGCCCGACGCGATCGTCGTCTGA

Upstream 100 bases:

>100_bases
CGCTTGTCGGCGCTTGTCGACGCTTGTCGACTCGGGGCAAGCTCAACCGTCCGCACCCAGGCAGTTGTTACCAGATCAAC
ACCCCGACCGGATAACCGTC

Downstream 100 bases:

>100_bases
GCCGGCTCGCGCCGGCGGGCGCACCATCGCGGGCTATGCAACAGCATCCTTGCGCGGACGTCCGCGCGGACGCTTGTGAC
TCACGATCGAGCCTTGGTCG

Product: putative ATP-binding protein ABC transporter

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVM
EAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQY
PGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVV
IQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELG
MTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMD
LPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV

Sequences:

>Translated_447_residues
MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVM
EAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQY
PGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVV
IQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELG
MTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMD
LPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV
>Mature_447_residues
MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVM
EAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQY
PGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVV
IQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELG
MTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMD
LPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=406, Percent_Identity=27.3399014778325, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI27363457, Length=300, Percent_Identity=28.6666666666667, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI40254938, Length=256, Percent_Identity=29.6875, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI217416386, Length=244, Percent_Identity=28.6885245901639, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI217035081, Length=192, Percent_Identity=31.7708333333333, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI41393593, Length=269, Percent_Identity=27.1375464684015, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI2367309, Length=269, Percent_Identity=26.3940520446097, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565180, Length=320, Percent_Identity=30.625, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17559152, Length=269, Percent_Identity=29.7397769516729, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321319, Length=316, Percent_Identity=27.8481012658228, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323282, Length=236, Percent_Identity=26.6949152542373, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI18859849, Length=349, Percent_Identity=28.6532951289398, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI22024280, Length=303, Percent_Identity=30.6930693069307, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24662575, Length=279, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 49123; Mature: 49123

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLF
CCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLG
HHHHHHCCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
TKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGV
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
LKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHH
IQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRM
HHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEECCCCC
GIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLR
CEEECCCCCCCCCCCEEEECCEEEEECCCCCCEECCCHHHHHHHHCCCCCCHHHHHHHHH
QYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILC
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QLDAHVPIKALSEELIPGFAEPDAIVV
HHCCCCCHHHHHHHHCCCCCCCCCEEC
>Mature Secondary Structure
MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLF
CCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLG
HHHHHHCCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
TKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGV
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
LKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHH
IQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRM
HHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEECCCCC
GIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLR
CEEECCCCCCCCCCCEEEECCEEEEECCCCCCEECCCHHHHHHHHCCCCCCHHHHHHHHH
QYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILC
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QLDAHVPIKALSEELIPGFAEPDAIVV
HHCCCCCHHHHHHHHCCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA