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The map label for this gene is cdh

Identifier: 121638170

GI number: 121638170

Start: 2538769

End: 2539551

Strand: Direct

Name: cdh

Synonym: BCG_2305

Alternate gene names: 121638170

Gene position: 2538769-2539551 (Clockwise)

Preceding gene: 121638169

Following gene: 121638171

Centisome position: 58.04

GC content: 57.47

Gene sequence:

>783_bases
GTGCCCAAAAGCCGACGGGCAGTCAGTCTAAGTGTCTTGATAGGTGCGGTGATAGCAGCTCTTGCCGGGGCGCTGATTGC
GGTAACCGTACCGGCGCGGCCGAATCGCCCTGAGGCCGACCGTGAAGCACTGTGGAAAATCGTGCACGACCGTTGCGAAT
TCGGCTATCGGCGTACCGGTGCGTACGCTCCCTGCACATTCGTGGATGAACAGTCTGGAACGGCGTTGTACAAAGCGGAT
TTTGATCCGTACCAGTTCCTTTTGATCCCGCTTGCTCGTATCACCGGAATCGAGGATCCCGCCCTACGGGAGTCAGCGGG
TCGCAATTACCTCTACGACGCTTGGGCCGCACGGTTCCTCGTTACCGCGCGCCTGAACAACTCACTTCCAGAGTCAGACG
TAGTCCTCACCATCAACCCGAAGAACGCGCGCACTCAGGATCAGCTGCACATCCACATATCGTGTTCGTCACCAACAACA
TCGGCAGCCCTGAGGAACGTGGATACCTCAGAGTACGTTGGCTGGAAGCAGCTCCCCATCGACCTCGGTGGTCGCAGGTT
TCAAGGATTGGCGGTTGACACGAAGGCGTTCGAATCCAGGAACCTGTTCCGGGACATCTACCTGAAGGTAACCGCTGACG
GCAAGAAAATGGAAAATGCATCGATTGCGGTTGCCAACGTAGCGCAGGACCAATTCCTGCTGCTCTTGGCAGAGGGAACT
GAGGACCAGCCCGTTGCAGCCGAGACTCTCCAAGACCACGACTGCTCCATCACCAAGTCCTGA

Upstream 100 bases:

>100_bases
GCGACATCCTGCGTGATCGGAAGGGCATAGCGCCATGGCAGGAACAACGCGAACCGGGCTGGGCGCCGTTCGGTTGGCTG
CACGAGCCCTCGGGCGCAAG

Downstream 100 bases:

>100_bases
TAGCACGATGCCAGCGGGCCACACGACAGGGCGCAGTGTGCGAACCTGACCCCGCCACGGCGGGCCGTTGATGGCATTTT
GCTAGTGTCGGAGCGGCAAT

Product: CDP-diacylglycerol pyrophosphatase

Products: NA

Alternate protein names: CDP-diacylglycerol phosphatidylhydrolase; CDP-diglyceride hydrolase

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKAD
FDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTT
SAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGT
EDQPVAAETLQDHDCSITKS

Sequences:

>Translated_260_residues
MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKAD
FDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTT
SAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGT
EDQPVAAETLQDHDCSITKS
>Mature_259_residues
PKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADF
DPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTS
AALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGTE
DQPVAAETLQDHDCSITKS

Specific function: Phospholipid biosynthesis. [C]

COG id: COG2134

COG function: function code I; CDP-diacylglycerol pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cdh family

Homologues:

Organism=Escherichia coli, GI1790352, Length=222, Percent_Identity=28.8288288288288, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDH_MYCBO (P63752)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_855960.1
- ProteinModelPortal:   P63752
- SMR:   P63752
- EnsemblBacteria:   EBMYCT00000016662
- GeneID:   1090403
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2311
- GeneTree:   EBGT00050000018626
- HOGENOM:   HBG565233
- OMA:   EIQDHEC
- ProtClustDB:   PRK05471
- BioCyc:   MBOV233413:MB2311-MONOMER
- BRENDA:   3.6.1.26
- HAMAP:   MF_00319
- InterPro:   IPR003763
- PIRSF:   PIRSF001273

Pfam domain/function: PF02611 CDH

EC number: =3.6.1.26

Molecular weight: Translated: 28609; Mature: 28478

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15eed40c)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTG
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFL
CCCCEEEEECCCCCEEEEECCCCHHHHEEEHHHHCCCCCCHHHHHCCCCEEHHHHHHHHH
VTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAALRNVDTSEYVGWKQLPI
EEEHHCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHCCCCHHCCCEEECCC
DLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGT
CCCCCEEEEEEECHHHHHHHCCEEEEEEEEEECCCCCCCCEEEEEEECCCEEEEEEECCC
EDQPVAAETLQDHDCSITKS
CCCCCHHHHHCCCCCEEECH
>Mature Secondary Structure 
PKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTG
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFL
CCCCEEEEECCCCCEEEEECCCCHHHHEEEHHHHCCCCCCHHHHHCCCCEEHHHHHHHHH
VTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAALRNVDTSEYVGWKQLPI
EEEHHCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHCCCCHHCCCEEECCC
DLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGT
CCCCCEEEEEEECHHHHHHHCCEEEEEEEEEECCCCCCCCEEEEEEECCCEEEEEEECCC
EDQPVAAETLQDHDCSITKS
CCCCCHHHHHCCCCCEEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972