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The map label for this gene is glpD1

Identifier: 121638132

GI number: 121638132

Start: 2501802

End: 2503352

Strand: Reverse

Name: glpD1

Synonym: BCG_2267c

Alternate gene names: 121638132

Gene position: 2503352-2501802 (Counterclockwise)

Preceding gene: 121638133

Following gene: 121638122

Centisome position: 57.23

GC content: 67.63

Gene sequence:

>1551_bases
GTGCTGATGCCCCACTCGGCTGCACTCAACGCGGCGCGTCGCTCCGCCGACCTGACCGCACTGGCCGACGGTGGCGCACT
CGACGTCATCGTGATAGGCGGCGGCATTACCGGTGTTGGCATTGCCTTAGATGCTGCCACCCGCGGTCTGACGGTGGCCT
TGGTGGAAAAGCATGATCTGGCGTTCGGCACCAGCCGCTGGAGCTCGAAGTTGGTGCACGGCGGTCTGCGCTATCTGGCC
AGCGGCAACGTGGGCATCGCCCGGCGCAGCGCCGTCGAACGCGGAATCCTGATGACACGCAACGCTCCTCATCTCGTGCA
TGCCATGCCGCAACTGGTCCCGTTGTTGCCGTCGATGGGTCACACCAAGCGGGCGTTGGTGCGTGCCGGTTTCCTGGCCG
GCGACGCTTTGCGGGTGCTAGCGGGTACGCCGGCGGCGACGTTGCCCCGATCGCGCCGAATCCCGGCGTCACGGGTGGTG
GAGATTGCTCCCACCGTTCGGCGGGACGGCCTCGACGGTGGTCTGCTCGCGTACGACGGGCAATTGATCGACGACGCCCG
GCTGGTCATGGCCGTCGCGCGCACCGCGGCCCAGCACGGCGCCCGCATCCTCACTTACGTGGGCGCGTCGAATGTCACCG
GCACTTCGGTGGAGTTGACCGACCGGCGCACCCGGCAGTCGTTCGCGCTGTCGGCGCGTGCCGTCATCAACGCGGCGGGC
GTGTGGGCGGGTGAGATCGACCCGTCCCTGAGGCTACGCCCCAGCCGCGGCACACATCTGGTCTTCGACGCGAAGTCGTT
TGCCAATCCGACTGCCGCGCTGACCATTCCGATCCCCGGTGAGCTGAACCGCTTCGTGTTCGCCATGCCCGAGCAGCTGG
GCCGGATCTATCTCGGGCTGACCGACGAAGACGCACCCGGCCCGATTCCCGATGTGCCACAACCGTCTTCGGAAGAGATC
ACGTTCCTGCTGGATACGGTGAACACCGCATTGGGGACGGCGGTCGGCACCAAGGATGTCATCGGTGCCTATGCGGGATT
GCGGCCGCTAATCGACACCGGCGGTGCTGGTGTCCAGGGCCGCACCGCCGACGTTTCGCGTGACCACGCTGTTTTTGAAT
CGCCGTCGGGCGTGATCAGTGTGGTCGGCGGCAAGCTGACGGAATACCGCTACATGGCAGAGGATGTGCTGAATCGCGCC
ATCACGCTGCGACACCTGCGAGCCGCGAAGTGCCGCACTCGCAACCTGCCGCTGATCGGCGCACCGGCGAACCCTGGGCC
GGCCCCCGGATCGGGCGCCGGATTGCCCGAGTCGCTGGTGGCGCGGTACGGGGCCGAGGCGGCCAACGTCGCTGCCGCCG
CCACATGTGAGCGGCCCACCGAGCCGGTCGCCGACGGCATCGACGTGACCCGGGCGGAGTTCGAATACGCGGTGACCCAT
GAGGGGGCGCTGGATGTGGACGATATCCTCGACCGCCGGACCCGGATCGGTCTGGTGCCACGGGATCGCGAGCGCGTAGT
CGCCGTGGCTAAGGAGTTCCTCAGCCGTTGA

Upstream 100 bases:

>100_bases
TGATCGCCCAGTCGACCATCCAGTCCGCGGACATCGTCGATTCGATCCTCGATTCCGCCGCGCTGGCCACCGAACTTACC
CACGCACTGAACGGATATTT

Downstream 100 bases:

>100_bases
GCGCGAGCAGACGCAGAGTCGCACTGCGCCGGCCGGCGCAGTGCGACTCTGCGTCTGCTCACCAGCGGTCAGCCGGCCAT
ACGCGCGCGGTCGAGGTGGC

Product: putative glycerol-3-phosphate dehydrogenase glpd1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDLAFGTSRWSSKLVHGGLRYLA
SGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMGHTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVV
EIAPTVRRDGLDGGLLAYDGQLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAG
VWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGLTDEDAPGPIPDVPQPSSEEI
TFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQGRTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRA
ITLRHLRAAKCRTRNLPLIGAPANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTH
EGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR

Sequences:

>Translated_516_residues
MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDLAFGTSRWSSKLVHGGLRYLA
SGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMGHTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVV
EIAPTVRRDGLDGGLLAYDGQLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAG
VWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGLTDEDAPGPIPDVPQPSSEEI
TFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQGRTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRA
ITLRHLRAAKCRTRNLPLIGAPANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTH
EGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR
>Mature_516_residues
MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDLAFGTSRWSSKLVHGGLRYLA
SGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMGHTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVV
EIAPTVRRDGLDGGLLAYDGQLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAG
VWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGLTDEDAPGPIPDVPQPSSEEI
TFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQGRTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRA
ITLRHLRAAKCRTRNLPLIGAPANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTH
EGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI285002233, Length=527, Percent_Identity=32.6375711574953, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI285002231, Length=527, Percent_Identity=32.6375711574953, Blast_Score=206, Evalue=3e-53,
Organism=Escherichia coli, GI2367226, Length=473, Percent_Identity=29.3868921775898, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788574, Length=488, Percent_Identity=30.5327868852459, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI115534726, Length=532, Percent_Identity=30.8270676691729, Blast_Score=168, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17509253, Length=528, Percent_Identity=31.25, Blast_Score=164, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6322036, Length=541, Percent_Identity=29.5748613678373, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI161077125, Length=528, Percent_Identity=30.8712121212121, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24653942, Length=528, Percent_Identity=30.8712121212121, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24653944, Length=528, Percent_Identity=30.8712121212121, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI20130025, Length=528, Percent_Identity=30.8712121212121, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586295, Length=535, Percent_Identity=30.6542056074766, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19921278, Length=533, Percent_Identity=26.078799249531, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPD1_MYCBO (P64183)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855922.1
- ProteinModelPortal:   P64183
- SMR:   P64183
- EnsemblBacteria:   EBMYCT00000015150
- GeneID:   1091414
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2273c
- GeneTree:   EBGT00050000015584
- HOGENOM:   HBG720894
- OMA:   HLDDLML
- ProtClustDB:   CLSK872035
- BioCyc:   MBOV233413:MB2273C-MONOMER
- BRENDA:   1.1.99.5
- InterPro:   IPR006076
- InterPro:   IPR000447
- PRINTS:   PR01001

Pfam domain/function: PF01266 DAO

EC number: =1.1.5.3

Molecular weight: Translated: 54177; Mature: 54177

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00977 FAD_G3PDH_1; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDL
CCCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCC
AFGTSRWSSKLVHGGLRYLASGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMG
EECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCC
HTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVVEIAPTVRRDGLDGGLLAYDG
CHHHHHHHHHHHCCCHHHHHCCCCHHCCCCCCCCCHHHHEECCCHHHHCCCCCCEEEECC
QLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAG
EECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCC
VWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGL
CEECCCCCCEEECCCCCCEEEEECHHHCCCCEEEEEECCCCCCHHEEECCHHCCEEEEEE
TDEDAPGPIPDVPQPSSEEITFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQG
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCCCC
RTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRAITLRHLRAAKCRTRNLPLIG
CCCCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
APANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTH
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCHHCCCCCCHHHEEEEEEC
EGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDL
CCCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCC
AFGTSRWSSKLVHGGLRYLASGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMG
EECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCC
HTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVVEIAPTVRRDGLDGGLLAYDG
CHHHHHHHHHHHCCCHHHHHCCCCHHCCCCCCCCCHHHHEECCCHHHHCCCCCCEEEECC
QLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAG
EECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCC
VWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGL
CEECCCCCCEEECCCCCCEEEEECHHHCCCCEEEEEECCCCCCHHEEECCHHCCEEEEEE
TDEDAPGPIPDVPQPSSEEITFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQG
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCCCC
RTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRAITLRHLRAAKCRTRNLPLIG
CCCCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
APANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTH
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCHHCCCCCCHHHEEEEEEC
EGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972