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The map label for this gene is yuaR [C]

Identifier: 121638106

GI number: 121638106

Start: 2474105

End: 2475667

Strand: Reverse

Name: yuaR [C]

Synonym: BCG_2241c

Alternate gene names: 121638106

Gene position: 2475667-2474105 (Counterclockwise)

Preceding gene: 121638111

Following gene: 121638105

Centisome position: 56.59

GC content: 65.77

Gene sequence:

>1563_bases
GTGGGCATGAGGCTGTCTCGCCGCGACAAGATCGCGCGCATGCTGTTGATCTGGGCCGCGCTCGCCGCCGTGGCGTTGGT
TCTTGTGGGCTGCATCCGCGTGGTCGGGGGACGCGCTCGTATGGCGGAGCCGAAGCTGGGCCAGCCGGTGGAGTGGACAC
CGTGCCGGTCGTCAAACCCGCAAGTAAAGATCCCCGGCGGCGCGTTATGCGGCAAGCTCGCTGTACCGGTCGACTACGAC
CGCCCCGATGGTGACGTGGCGGCGCTGGCGCTGATTCGCTTTCCGGCGACGGGAGACAAGATCGGTTCGCTGGTCATAAA
TCCCGGTGGACCCGGCGAATCCGGTATCGAGGCCGCCTTGGGCGTCTTCCAGACATTGCCGAAGCGGGTGCACGAAAGGT
TCGACCTGGTTGGGTTCGACCCCCGCGGGGTGGCGTCGTCCCGGCCGGCGATCTGGTGCAACTCCGATGCCGACAACGAC
CGGCTGCGGGCCGAGCCGCAGGTTGACTACAGCCGGGAGGGTGTGGCGCACATCGAGAACGAGACCAAGCAATTCGTCGG
TCGCTGTGTGGACAAGATGGGCAAGAACTTTCTGGCCCATGTCGGGACGGTCAACGTCGCCAAGGACCTGGATGCCATTC
GCGCGGCGTTGGGCGACGACAAGCTGACCTACCTGGGCTACTCGTACGGCACCCGGATCGGCTCCGCGTATGCCGAGGAA
TTTCCGCAGCGGGTGCGGGCAATGATTCTCGACGGTGCCGTCGACCCCAATGCCGATCCCATCGAGGCGGAGCTGCGCCA
GGCCAAGGGCTTCCAGGACGCGTTCAACAACTATGCCGCCGACTGCGCCAAGAACGCGGGCTGCCCGCTGGGCGCCGACC
CGGCCAAAGCCGTCGAGGTCTACCACAGCCTGGTCGATCCGTTGGTCGACCCGGACAACCCGAGGATCAGCAGGCCGGCG
CGCACGAAGGATCCGCGCGGGCTGAGTTATAGCGACGCCATCGTGGGCACCATTATGGCGCTGTACTCACCGAATCTGTG
GCAACACTTGACCGACGGGCTGTCGGAGCTGGTCGACAATCGCGGAGACACCCTGCTGGCTCTGGCCGACATGTACATGC
GTCGGGACTCGCACGGCCGCTACAACAATTCCGGTGACGCGCGGGTGGCGATCAATTGCGTCGATCAGCCCCCGGTTACC
GATCGCGACAAGGTCATCGACGAAGACCGCCGCGCCCGGGAGATCGCACCGTTCATGAGCTACGGGAAGTTCACCGGTGA
TGCGCCGCTGGGCACCTGCGCGTTCTGGCCGGTGCCACCCACAAGTCAGCCCCATGCCGTCTCGGCGCCCGGCCTAGTGC
CGACGGTGGTGGTATCCACCACCCATGACCCGGCGACGCCGTACAAGGCCGGGGTCGACCTGGCGAACCAGCTTCGCGGT
TCGTTGCTGACCTTCGACGGAACCCAGCACACGGTGGTATTCCAGGGCGACAGCTGCATTGACGAGTACGTGACGGCGTA
TTTGATCGGCGGCACCACGCCGCCCAGCGGCGCCAAGTGCTAG

Upstream 100 bases:

>100_bases
GACGAGTTCGCCATCGGCGATGGCAGGACTGCTGGCAGCGGCCGGTTAGTCGGCCGACGGTGGCCGCTGGCCAGGATCTC
GGGTCTGCTCTGGCAGCATT

Downstream 100 bases:

>100_bases
CGGGGCGAAGAAACGAAGGTGTGATCATTTCGCGCCGTCACAGGTATTCGCCGGTGAGACGATGGCGGCCATGTGGCGCC
GCAGACCGTTGAGCTCGGCG

Product: putative exported protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYD
RPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADND
RLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEE
FPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPA
RTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVT
DRDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRG
SLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC

Sequences:

>Translated_520_residues
MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYD
RPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADND
RLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEE
FPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPA
RTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVT
DRDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRG
SLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
>Mature_519_residues
GMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYDR
PDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDR
LRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEEF
PQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPAR
TKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTD
RDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRGS
LLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2224_MYCTU (P65823)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   D70776
- RefSeq:   NP_216740.1
- RefSeq:   NP_336753.1
- ProteinModelPortal:   P65823
- SMR:   P65823
- EnsemblBacteria:   EBMYCT00000002237
- EnsemblBacteria:   EBMYCT00000071125
- GeneID:   887857
- GeneID:   924145
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2282
- KEGG:   mtu:Rv2224c
- TIGR:   MT2282
- TubercuList:   Rv2224c
- GeneTree:   EBGT00050000016435
- HOGENOM:   HBG732622
- OMA:   DGHTAYG
- ProtClustDB:   CLSK791707
- GO:   GO:0005829
- GO:   GO:0009405
- InterPro:   IPR000073

Pfam domain/function: PF00561 Abhydrolase_1

EC number: NA

Molecular weight: Translated: 55925; Mature: 55794

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: ACT_SITE 228-228 ACT_SITE 463-463 ACT_SITE 490-490

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
QVKIPGGALCGKLAVPVDYDRPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAAL
CEECCCCHHHCCEECCCCCCCCCCHHHEEHHHCCCCCCCCCCEEEECCCCCCCHHHHHHH
GVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDRLRAEPQVDYSREGVAHIEN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
ETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
FPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
YHSLVDPLVDPDNPRISRPARTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
RGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTDRDKVIDEDRRAREIAPFMS
CCCEEHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHCHHHHHHHHHHHHH
YGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRG
HCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
SLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
CEEEECCCCEEEEECCCHHHHHHHHEEEECCCCCCCCCCC
>Mature Secondary Structure 
GMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
QVKIPGGALCGKLAVPVDYDRPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAAL
CEECCCCHHHCCEECCCCCCCCCCHHHEEHHHCCCCCCCCCCEEEECCCCCCCHHHHHHH
GVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDRLRAEPQVDYSREGVAHIEN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
ETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
FPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
YHSLVDPLVDPDNPRISRPARTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
RGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTDRDKVIDEDRRAREIAPFMS
CCCEEHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHCHHHHHHHHHHHHH
YGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRG
HCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
SLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
CEEEECCCCEEEEECCCHHHHHHHHEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036