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The map label for this gene is cobLb [H]

Identifier: 121637957

GI number: 121637957

Start: 2312627

End: 2313511

Strand: Reverse

Name: cobLb [H]

Synonym: BCG_2091c

Alternate gene names: 121637957

Gene position: 2313511-2312627 (Counterclockwise)

Preceding gene: 121637958

Following gene: 121637956

Centisome position: 52.89

GC content: 69.6

Gene sequence:

>885_bases
TTGCCGCACGTGTCCGCGGTGACGTTGGCGTGCGCCCGGATGGGCTGGAACGTGTATGACACCGAGGTGATCAGCCTGGT
CACCGCGCAACCACACACCGCGGTGCGCCGCGGCGGCCGGGCCATCGTGCTGTCCGGCGATCGGTCCACCCCGCAGGCGC
TGGCGGTGCTGCTGACCGAGCACGGTCGCGGTGACTCCAAGTTCAGCGTGCTCGAACAGCTTGGCGGCCCGGCCGAACGC
CGCCGCGACGGTACGGCCCGGGCATGGGCCTGCGACCCACCCCTCGATGTCGATGAGCTCAACGTGATCGCCGTGCGCTA
CCTGCCCGACGAGCGCACGTCGTGGGCACCCGACGAGGCATTCGCGCACGACGGGCAGATCACCAAACACCCAATCCGCG
TGCTGACCCTGGCTGCGCTGGCGCCAAGGCCCGGGCAGCGGTTATGGGACGTCGGCGCGGGCTCAGGCGCCATCGCGGTC
CAGTGGTGTCGGAGCTGGCCGGGCTGCACCGCGGTGGCGTTCGAGCGCGACGAACGGCGCCGCCGCAACATTGGGTTCAA
TGCCGCGGCCTTCGGGGTGAGCGTCGACGTGCGCGGCGACGCGCCCGATGCGTTCGACGACGCCGCACGGCCGTCGGTGA
TTTTTCTTGGCGGTGGTGTAACCCAGCCAGGCCTGCTTGAGGCCTGCCTGGACAGCCTGCCCGCAGGCGGGAACTTGGTC
GCCAACGCTGTCACCGTCGAATCGGAAGCCGCTCTGGCGCATGCATATTCGCGCCTCGGTGGCGAGCTACGACGATTCCA
GCACTATCTCGGCGAACCGCTGGGCGGCTTCACCGGTTGGCGCCCACAGCTGCCGGTCACCCAGTGGTCGGTGACCAAGC
GATGA

Upstream 100 bases:

>100_bases
GATGGGGCTGACCTACACGTGGTTGCCAGCGGCGACCCGTTGTTGCATGGTATCGGCTCCACCCTGATCCGGCTGTTCGG
CCACGACAACGTGACCGTGT

Downstream 100 bases:

>100_bases
CGGTCTATTTCATCGGAGCGGGCCCCGGCGCCGCCGACCTAATCACCGTCCGCGGCCAACGGCTCCTGCAACGATGCCCG
GTGTGCCTGTATGCGGGTTC

Product: putative precorrin-6y methyltransferase CobLb

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAER
RRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAV
QWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLV
ANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR

Sequences:

>Translated_294_residues
MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAER
RRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAV
QWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLV
ANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
>Mature_293_residues
PHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERR
RDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQ
WCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVA
NAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 31617; Mature: 31486

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE
CCCHHHHHHHHHHHCCCCCCHHEEEEEECCCHHHHHCCCCEEEEECCCCCHHHHHHHHHH
HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEA
CCCCCHHHHHHHHHCCHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHH
FAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERR
HCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEHHCCCCCEEEEECCHHHH
RRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLV
HHCCCCCEEEEEEEEEECCCCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEE
ANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE
CCHHHHHHHHHHHCCCCCCHHEEEEEECCCHHHHHCCCCEEEEECCCCCHHHHHHHHHH
HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEA
CCCCCHHHHHHHHHCCHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHH
FAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERR
HCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEHHCCCCCEEEEECCHHHH
RRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLV
HHCCCCCEEEEEEEEEECCCCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEE
ANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]