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The map label for this gene is cobLa [H]

Identifier: 121637958

GI number: 121637958

Start: 2313453

End: 2313641

Strand: Reverse

Name: cobLa [H]

Synonym: BCG_2092c

Alternate gene names: 121637958

Gene position: 2313641-2313453 (Counterclockwise)

Preceding gene: 121637959

Following gene: 121637957

Centisome position: 52.89

GC content: 65.08

Gene sequence:

>189_bases
ATGCTGCCCGCGGTGCAAGGCCTGTCACCGGATGGGGCTGACCTACACGTGGTTGCCAGCGGCGACCCGTTGTTGCATGG
TATCGGCTCCACCCTGATCCGGCTGTTCGGCCACGACAACGTGACCGTGTTTGCCGCACGTGTCCGCGGTGACGTTGGCG
TGCGCCCGGATGGGCTGGAACGTGTATGA

Upstream 100 bases:

>100_bases
ACCCGGCCCGGCGTGGGCCACAGTAATTTACGGCTCGAAACGGCAACTTGCCCTGCTCGACGATACCGTCACCGCCGAGC
GCTGGGAGTGGCCGACGCCG

Downstream 100 bases:

>100_bases
CACCGAGGTGATCAGCCTGGTCACCGCGCAACCACACACCGCGGTGCGCCGCGGCGGCCGGGCCATCGTGCTGTCCGGCG
ATCGGTCCACCCCGCAGGCG

Product: putative precorrin-6y methyltransferase CobLa

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 62; Mature: 62

Protein sequence:

>62_residues
MLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVFAARVRGDVGVRPDGLERV

Sequences:

>Translated_62_residues
MLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVFAARVRGDVGVRPDGLERV
>Mature_62_residues
MLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVFAARVRGDVGVRPDGLERV

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 6442; Mature: 6442

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVFAARVRGDVGVRPDGLE
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCC
RV
CC
>Mature Secondary Structure
MLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVFAARVRGDVGVRPDGLE
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCC
RV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]