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The map label for this gene is cobM [H]

Identifier: 121637956

GI number: 121637956

Start: 2311875

End: 2312630

Strand: Reverse

Name: cobM [H]

Synonym: BCG_2090c

Alternate gene names: 121637956

Gene position: 2312630-2311875 (Counterclockwise)

Preceding gene: 121637957

Following gene: 121637955

Centisome position: 52.87

GC content: 67.2

Gene sequence:

>756_bases
ATGACGGTCTATTTCATCGGAGCGGGCCCCGGCGCCGCCGACCTAATCACCGTCCGCGGCCAACGGCTCCTGCAACGATG
CCCGGTGTGCCTGTATGCGGGTTCGATCATGCCCGACGACCTGTTGGCGCAGTGTCCGCCCGGCGCGACGATTGTCGACA
CCGGTCCGCTGACCCTCGAACAAATCGTGCGCAAACTTGCCGACGCCGACGCCGACGGCCGCGACGTTGCCCGGCTGCAT
TCCGGCGACCCGTCGCTGTACAGCGCGCTGGCCGAACAGTGCCGCGAACTCGACGCGCTGGGCATCGGCTACGAAATCGT
GCCGGGCGTACCGGCTTTTGCCGCAGCCGCAGCGGCGCTAAAGCGCGAACTCACCGTGCCGGGTGTGGCGCAGACGGTGA
CGCTCACCCGGGTGGCGACGCTGTCCACACCCATGCCGCCCGGTGAGGACCTGGCCGCGCTCGCCCGATCCCGCGCCACT
CTGGTCTTGCACCTGGCCGCAGCCCAGATCGACGCCATCGTTCCGCGACTGCTAGACGGTGGTTACCGACCCGAAACGCC
GGTTGCGGTGGTGGCTTTCGCGAGTTGGCCGCAACAGCGGACGCTACGCGGCACGTTGGCCGATATCGCCGCGCGGATGC
ACGATGCCAAGATCACCAGGACCGCCGTGATCGTTGTTGGCGACGTGCTGACCGCTGAGGGCTTTACCGACAGCTACCTA
TATTCGGTGGCACGGCACGGTCGGTATGCACAGTGA

Upstream 100 bases:

>100_bases
GCGAGCTACGACGATTCCAGCACTATCTCGGCGAACCGCTGGGCGGCTTCACCGGTTGGCGCCCACAGCTGCCGGTCACC
CAGTGGTCGGTGACCAAGCG

Downstream 100 bases:

>100_bases
CCCGGGTGTTGTTGCTCGGCGGCACCGCCGAGGGCCGTGCGCTGGCGAAAGAGTTGCAACCCACACGTTGAGATCGTCAG
CTCGCTGGCCGGCCGGGTAC

Product: putative precorrin-4 C11-methyltransferase CobM

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLEQIVRKLADADADGRDVARLH
SGDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAALKRELTVPGVAQTVTLTRVATLSTPMPPGEDLAALARSRAT
LVLHLAAAQIDAIVPRLLDGGYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYL
YSVARHGRYAQ

Sequences:

>Translated_251_residues
MTVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLEQIVRKLADADADGRDVARLH
SGDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAALKRELTVPGVAQTVTLTRVATLSTPMPPGEDLAALARSRAT
LVLHLAAAQIDAIVPRLLDGGYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYL
YSVARHGRYAQ
>Mature_250_residues
TVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLEQIVRKLADADADGRDVARLHS
GDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAALKRELTVPGVAQTVTLTRVATLSTPMPPGEDLAALARSRATL
VLHLAAAQIDAIVPRLLDGGYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYLY
SVARHGRYAQ

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=235, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26439; Mature: 26308

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLE
CEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCEEEECCCCCHH
QIVRKLADADADGRDVARLHSGDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAAL
HHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
KRELTVPGVAQTVTLTRVATLSTPMPPGEDLAALARSRATLVLHLAAAQIDAIVPRLLDG
HHHCCCCCCHHHHHHHHHHECCCCCCCCHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHCC
GYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYL
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHCCCCHHHHH
YSVARHGRYAQ
HHHHHCCCCCC
>Mature Secondary Structure 
TVYFIGAGPGAADLITVRGQRLLQRCPVCLYAGSIMPDDLLAQCPPGATIVDTGPLTLE
EEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCEEEECCCCCHH
QIVRKLADADADGRDVARLHSGDPSLYSALAEQCRELDALGIGYEIVPGVPAFAAAAAAL
HHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
KRELTVPGVAQTVTLTRVATLSTPMPPGEDLAALARSRATLVLHLAAAQIDAIVPRLLDG
HHHCCCCCCHHHHHHHHHHECCCCCCCCHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHCC
GYRPETPVAVVAFASWPQQRTLRGTLADIAARMHDAKITRTAVIVVGDVLTAEGFTDSYL
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHCCCCHHHHH
YSVARHGRYAQ
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]