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The map label for this gene is cobK [H]

Identifier: 121637955

GI number: 121637955

Start: 2311143

End: 2311838

Strand: Reverse

Name: cobK [H]

Synonym: BCG_2089c

Alternate gene names: 121637955

Gene position: 2311838-2311143 (Counterclockwise)

Preceding gene: 121637956

Following gene: 121637953

Centisome position: 52.85

GC content: 66.09

Gene sequence:

>696_bases
GTGCGCTGGCGAAAGAGTTGCAACCCACACGTTGAGATCGTCAGCTCGCTGGCCGGCCGGGTACCCAACCCTGCCCTGCC
GATCGGTCCGGTGCGCATCGGCGGGTTCGGCGGTGTCGAGGGGCTGCGCGGTTGGCTGCGAGAGGAGCGCATCGATGCCG
TCGTCGACGCCACCCACCCCTTCGCGGTAACCATCACCGCGCACGCCGCGCAGGTGTGCGGTGAGCTCGGGCTCCCGTAC
CTGGTACTGGCTCGCCCGCCGTGGGATCCCGGTACCGCCATCATCGCGGTATCGGACATCGAGGCTGCAGACGTTGTTGC
TGAACAAGGTTATTCGCGAGTGTTCCTGACCACCGGACGCTCGGGTATTGCGGCCTTCGCCAACAGCGACGCGTGGTTTT
TGATCCGCGTGGTTACCGCGCCCGATGGCACCGCCCTGCCGCGGCGGCACAAACTGGTGCTATCTCGCGGGCCATATGGT
TACCACGATGAGTTCGCACTGCTGCGTGAGCAGCGCATCGACGCATTGGTCACCAAGAACAGCGGTGGCAAGATGACCCG
AGCGAAGCTGGATGCCGCTGCTGCGCTGGGTATTTCGGTGGTCATGATAGCGCGCCCGCTGCTGCCGGCTGGGGTAGCGG
CGGTCGATTCTGTCCACCGGGCCGCCATGTGGGTGGCCGGTCTGCCTAGCCGGTGA

Upstream 100 bases:

>100_bases
CGCTGAGGGCTTTACCGACAGCTACCTATATTCGGTGGCACGGCACGGTCGGTATGCACAGTGACCCGGGTGTTGTTGCT
CGGCGGCACCGCCGAGGGCC

Downstream 100 bases:

>100_bases
GGTCGTCGGGCTCCGCGTCGGCAAGCAGCGCATCGCGCGCTCGAGCGACACGGGATCGGATGGTGCCCACCGGGCAGCCG
CACACCGCCGCGGCGTCCGC

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRWRKSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVTITAHAAQVCGELGLPY
LVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYG
YHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR

Sequences:

>Translated_231_residues
MRWRKSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVTITAHAAQVCGELGLPY
LVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYG
YHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
>Mature_231_residues
MRWRKSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVTITAHAAQVCGELGLPY
LVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYG
YHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 24581; Mature: 24581

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWRKSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHP
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
FAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGR
EEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHCCCCEEEEEECC
SGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKN
CCEEEEECCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEEEEC
SGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRWRKSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHP
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
FAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGR
EEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHCCCCEEEEEECC
SGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKN
CCEEEEECCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEEEEC
SGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]