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The map label for this gene is 121637916

Identifier: 121637916

GI number: 121637916

Start: 2260093

End: 2262138

Strand: Reverse

Name: 121637916

Synonym: BCG_2049c

Alternate gene names: NA

Gene position: 2262138-2260093 (Counterclockwise)

Preceding gene: 121637917

Following gene: 121637915

Centisome position: 51.71

GC content: 66.86

Gene sequence:

>2046_bases
GTGCTGATGACCGCAGCGGCTGATGTCACCCGGCGCTCGCCGCGGCGCGTGTTCCGTGACCGCCGCGAGGCCGGCCGGGT
GCTGGCGGAATTACTCGCCGCCTATCGGGACCAGCCGGACGTGATTGTGCTCGGCTTGGCCCGGGGTGGCCTCCCGGTCG
CATGGGAGGTTGCCGCGGCACTGCATGCCCCGCTAGACGCCTTCGTCGTGCGCAAACTTGGTGCCCCGGGGCATGACGAG
TTCGCCGTTGGTGCACTGGCCAGCGGCGGCCGCGTCGTGGTCAATGACGACGTCGTGCGGGGCCTGCGGATCACACCGCA
GCAACTGCGCGACATCGCCGAACGTGAGGGTCGGGAACTGCTTCGGCGCGAGTCCGCCTACCGCGGCGAGCGCCCGCCCA
CCGATATCACCGGCAAGACGGTCATTGTCGTCGATGACGGTTTGGCCACCGGCGCAAGCATGTTCGCGGCGGTACAGGCA
TTGCGCGATGCGCAACCAGCGCAGATCGTGATTGCCGTGCCGGCGGCGCCGGAGTCCACGTGCCGGGAGTTCGCCGGCCT
CGTCGACGACGTTGTGTGCGCGACCATGCCGACCCCGTTCCTGGCCGTCGGTGAGTCGTTTTGGGACTTCCGGCAGGTCA
CCGACGAGGAGGTCCGCCGGCTCCTGGCCACCCCGACCGCTGGGCCGTCGCTGCGCCGGCCCGCGGCGTCAACGGCGGCC
GATGTTCTGCGCAGAGTCGCGATCGACGCCCCCGGGGGTGTTCCGACGCACGAGGTGTTGGCGGAGCTGGTCGGCGATGC
ACGAATCGTGTTGATCGGCGAAAGCTCGCACGGCACACACGAGTTCTACCAGGCCCGGGCCGCCATGACACAGTGGCTGA
TCGAGGAGAAGGGCTTTGGTGCGGTAGCCGCCGAGGCGGACTGGCCCGACGCCTACCGGGTCAATCGGTACGTTCGCGGC
CTCGGCGAGGACACCAACGCTGACGAGGCGCTTAGCGGATTCGAGCGGTTTCCCGCCTGGATGTGGCGCAACACCGTGGT
CCGAGATTTTGTGGAATGGCTGCGCACACGCAACCAGCGCTACGAGTCGGGCGCGCTGCGGCAAGCCGGCTTCTACGGTC
TGGATCTTTACAGCCTGCATCGGTCGATCCAAGAGGTGATCAGCTATCTCGACAAGGTCGACCCGCGTGCGGCGGCACGG
GCGCGGGCCCGGTATGCGTGCTTCGACCATGCCTGCGCCGATGACGGTCAGGCGTACGGATTCGCGGCCGCATTCGGCGC
CGGTCCGTCGTGCGAACGTGAAGCCGTCGAGCAACTGGTCGACGTTCAGCGCAATGCCCTGGCGTATGCGCGCCAAGACG
GGCTGCTTGCCGAGGACGAACTGTTCTACGCCCAGCAAAACGCGCAGACGGTGCGCGACGCAGAGGTGTATTACCGGGCC
ATGTTCAGTGGACGCGTTACCTCGTGGAACCTGCGCGACCAGCACATGGCGCAGACCCTTGGCAGTTTGCTGACGCATTT
GGACCGACACCTCGATGCGCCGCCGGCGCGAATAGTGGTGTGGGCTCATAACTCCCACGTGGGTGACGCACGCGCTACCG
AGGTGTGGGCCGACGGGCAGCTCACCCTCGGCCAGATAGTCCGTGAGCGATACGGTGACGAGTCGCGCAGCATCGGATTC
AGCACGTACACGGGCACCGTCACCGCGGCCAGCGAATGGGGTGGTATCGCCCAACGCAAAGCGGTTCGGCCGGCACTGCA
CGGCAGTGTCGAGGAGCTCTTCCACCAGACTGCAGACAGTTTCCTGGTGTCAGCGCGGCTAAGCCGCGACGCCGAAGCCC
CGCTGGACGTTGTCCGGTTGGGACGTGCCATCGGCGTCGTTTATCTACCGGCAACGGAACGGCAAAGTCACTACTTGCAC
GTGCGGCCCGCCGACCAGTTCGACGCCATGATCCACATCGATCAGACCCGTGCCCTGGAACCTCTCGAGGTGACGAGCCG
GTGGATCGCCGGCGAGAACCCGGAAACCTACCCGACCGGTCTGTAG

Upstream 100 bases:

>100_bases
CCTACGACAAGGGCATTCTTACTGTGTCGGTGGCGGTTTCGGAAGGGAAGCCAACCGAAAAGCACATTCAGATCCGGTCC
ACCAACTGACCACTGGGTCC

Downstream 100 bases:

>100_bases
CGCAGAGTCCACGACGATGACGGAGCCAGCGGCGTGGGACGAAGGCAAGCCGCGAATCATCACTTTGACCATGAACCCCG
CCTTGGACATCACGACGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGGLPVAWEVAAALHAPLDAFVVRKLGAPGHDE
FAVGALASGGRVVVNDDVVRGLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLATGASMFAAVQA
LRDAQPAQIVIAVPAAPESTCREFAGLVDDVVCATMPTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRPAASTAA
DVLRRVAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGFGAVAAEADWPDAYRVNRYVRG
LGEDTNADEALSGFERFPAWMWRNTVVRDFVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAAR
ARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRNALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRA
MFSGRVTSWNLRDQHMAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQIVRERYGDESRSIGF
STYTGTVTAASEWGGIAQRKAVRPALHGSVEELFHQTADSFLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLH
VRPADQFDAMIHIDQTRALEPLEVTSRWIAGENPETYPTGL

Sequences:

>Translated_681_residues
MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGGLPVAWEVAAALHAPLDAFVVRKLGAPGHDE
FAVGALASGGRVVVNDDVVRGLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLATGASMFAAVQA
LRDAQPAQIVIAVPAAPESTCREFAGLVDDVVCATMPTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRPAASTAA
DVLRRVAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGFGAVAAEADWPDAYRVNRYVRG
LGEDTNADEALSGFERFPAWMWRNTVVRDFVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAAR
ARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRNALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRA
MFSGRVTSWNLRDQHMAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQIVRERYGDESRSIGF
STYTGTVTAASEWGGIAQRKAVRPALHGSVEELFHQTADSFLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLH
VRPADQFDAMIHIDQTRALEPLEVTSRWIAGENPETYPTGL
>Mature_681_residues
MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGGLPVAWEVAAALHAPLDAFVVRKLGAPGHDE
FAVGALASGGRVVVNDDVVRGLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLATGASMFAAVQA
LRDAQPAQIVIAVPAAPESTCREFAGLVDDVVCATMPTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRPAASTAA
DVLRRVAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGFGAVAAEADWPDAYRVNRYVRG
LGEDTNADEALSGFERFPAWMWRNTVVRDFVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAAR
ARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRNALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRA
MFSGRVTSWNLRDQHMAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQIVRERYGDESRSIGF
STYTGTVTAASEWGGIAQRKAVRPALHGSVEELFHQTADSFLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLH
VRPADQFDAMIHIDQTRALEPLEVTSRWIAGENPETYPTGL

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2030_MYCTU (O53475)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842578
- PIR:   E70942
- RefSeq:   NP_216546.1
- RefSeq:   NP_336554.1
- ProteinModelPortal:   O53475
- SMR:   O53475
- EnsemblBacteria:   EBMYCT00000002783
- EnsemblBacteria:   EBMYCT00000072477
- GeneID:   887536
- GeneID:   924661
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2089
- KEGG:   mtu:Rv2030c
- TIGR:   MT2089
- TubercuList:   Rv2030c
- GeneTree:   EBGT00050000015242
- HOGENOM:   HBG400409
- OMA:   APLDAFI
- ProtClustDB:   CLSK791575
- GO:   GO:0005829
- InterPro:   IPR007815
- InterPro:   IPR000836

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran

EC number: NA

Molecular weight: Translated: 74931; Mature: 74931

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGGLPVAWEVAAA
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
LHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVRGLRITPQQLRDIAEREGREL
HHCCHHHHHHHHCCCCCCCCHHHEEECCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHHH
LRRESAYRGERPPTDITGKTVIVVDDGLATGASMFAAVQALRDAQPAQIVIAVPAAPEST
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
CREFAGLVDDVVCATMPTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRPAASTAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLRRVAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGFG
HHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
AVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNTVVRDFVEWLRTRNQR
EEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
YESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAARARARYACFDHACADDGQAYG
HHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
FAAAFGAGPSCEREAVEQLVDVQRNALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRA
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
MFSGRVTSWNLRDQHMAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQ
HHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHEEECCCC
LTLGQIVRERYGDESRSIGFSTYTGTVTAASEWGGIAQRKAVRPALHGSVEELFHQTADS
CHHHHHHHHHHCCCHHCCCEEEECCEEEECHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
FLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLHVRPADQFDAMIHIDQTRALE
HHHHHHHCCCCCCCHHHHHHHHHHCEEEECCCCCCCCEEEECCCCCCCCEEEECHHCCCC
PLEVTSRWIAGENPETYPTGL
HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGGLPVAWEVAAA
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
LHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVRGLRITPQQLRDIAEREGREL
HHCCHHHHHHHHCCCCCCCCHHHEEECCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHHH
LRRESAYRGERPPTDITGKTVIVVDDGLATGASMFAAVQALRDAQPAQIVIAVPAAPEST
HHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
CREFAGLVDDVVCATMPTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRPAASTAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLRRVAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGFG
HHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
AVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNTVVRDFVEWLRTRNQR
EEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
YESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAARARARYACFDHACADDGQAYG
HHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
FAAAFGAGPSCEREAVEQLVDVQRNALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRA
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
MFSGRVTSWNLRDQHMAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQ
HHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHEEECCCC
LTLGQIVRERYGDESRSIGFSTYTGTVTAASEWGGIAQRKAVRPALHGSVEELFHQTADS
CHHHHHHHHHHCCCHHCCCEEEECCEEEECHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
FLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLHVRPADQFDAMIHIDQTRALE
HHHHHHHCCCCCCCHHHHHHHHHHCEEEECCCCCCCCEEEECCCCCCCCEEEECHHCCCC
PLEVTSRWIAGENPETYPTGL
HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036