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The map label for this gene is ephB [H]

Identifier: 121637843

GI number: 121637843

Start: 2193187

End: 2194257

Strand: Direct

Name: ephB [H]

Synonym: BCG_1977

Alternate gene names: 121637843

Gene position: 2193187-2194257 (Clockwise)

Preceding gene: 121637842

Following gene: 121637844

Centisome position: 50.14

GC content: 66.48

Gene sequence:

>1071_bases
GTGTCGCAGGTCCATCGAATCCTGAACTGCCGGGGCACCCGCATCCATGCCGTGGCGGACAGCCCACCCGACCAACAGGG
ACCGTTGGTGGTGTTGCTGCACGGGTTTCCGGAGTCCTGGTACTCGTGGCGGCATCAGATTCCCGCGCTTGCCGGCGCGG
GCTACCGCGTGGTGGCCATCGACCAGCGCGGGTATGGCCGCTCGTCGAAATACCGGGTGCAAAAGGCCTACCGCATCAAG
GAATTGGTTGGCGACGTCGTGGGCGTCCTCGACTCCTATGGTGCGGAGCAGGCTTTCGTGGTGGGCCACGACTGGGGTGC
GCCGGTCGCCTGGACCTTCGCCTGGCTGCACCCCGACCGATGCGCCGGCGTGGTGGGAATCAGCGTTCCGTTTGCCGGTC
GCGGCGTGATCGGCCTGCCGGGCAGCCCGTTCGGCGAGCGCCGTCCCAGCGACTACCACCTGGAGCTGGCCGGGCCCGGA
AGGGTCTGGTATCAGGACTATTTCGCCGTGCAGGACGGCATCATCACCGAGATCGAGGAAGACTTGCGGGGCTGGCTGCT
CGGGTTGACCTACACCGTTTCCGGTGAGGGGATGATGGCGGCGACCAAGGCGGCCGTCGACGCGGGCGTCGACCTGGAGT
CCATGGACCCGATCGACGTGATCCGTGCCGGACCGCTGTGTATGGCCGAAGGCGCGCGGCTCAAGGACGCGTTCGTCTAC
CCGGAGACCATGCCGGCCTGGTTCACCGAGGCCGATCTCGATTTCTACACTGGCGAATTCGAACGTTCCGGGTTCGGCGG
GCCGCTGAGCTTCTACCACAACATCGACAACGACTGGCACGACCTGGCCGACCAGCAAGGCAAGCCGCTCACCCCGCCGG
CTCTGTTCATCGGCGGCCAGTATGACGTCGGCACCATCTGGGGCGCGCAGGCCATCGAGCGTGCGCACGAAGTCATGCCG
AACTACCGCGGCACCCACATGATCGCCGACGTCGGACACTGGATCCAGCAGGAAGCGCCCGAAGAGACCAACCGGCTGTT
GCTCGACTTCCTAGGCGGGCTGCGGCCGTGA

Upstream 100 bases:

>100_bases
GATTGTCGGGCCAGAAGACGTTGATTGCCCGCAACTACGAAAATCATCCGATACCAGCCGAACCCGCGGACCAACTTGTA
AACGCTTAGGAGAGCCCAAC

Downstream 100 bases:

>100_bases
GCTGCACCTTCGACATGGTCCCGGAGACCGTCGATCATCTCGACGAGGTCGGGCTGCGGCGGGTCTTCGGCTGCTTTCCG
TGCGGCGTGATCGCCGTCTG

Product: putative epoxide hydrolase ephB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIK
ELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPG
RVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY
PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMP
NYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP

Sequences:

>Translated_356_residues
MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIK
ELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPG
RVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY
PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMP
NYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP
>Mature_355_residues
SQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKE
LVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGR
VWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYP
ETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPN
YRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=326, Percent_Identity=32.2085889570552, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI218777837, Length=341, Percent_Identity=24.633431085044, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI218777840, Length=353, Percent_Identity=26.3456090651558, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI13376164, Length=353, Percent_Identity=26.3456090651558, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554012, Length=349, Percent_Identity=28.9398280802292, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17562298, Length=349, Percent_Identity=23.2091690544413, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 39298; Mature: 39167

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI
CCHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHCCCHHCCCCEEEEEE
DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCH
CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE
HCEEEEEECCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHH
DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY
HHHHEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCEEECCCCCCCEEEEC
PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ
CCCCCCCEECCCCCEECCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCCCCCCEEEECCC
YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI
CHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHCCCHHCCCCEEEEEE
DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCH
CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE
HCEEEEEECCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHH
DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY
HHHHEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCEEECCCCCCCEEEEC
PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ
CCCCCCCEECCCCCEECCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCCCCCCEEEECCC
YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]