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The map label for this gene is 121637476

Identifier: 121637476

GI number: 121637476

Start: 1773339

End: 1773947

Strand: Direct

Name: 121637476

Synonym: BCG_1607

Alternate gene names: NA

Gene position: 1773339-1773947 (Clockwise)

Preceding gene: 121637475

Following gene: 121637477

Centisome position: 40.54

GC content: 64.86

Gene sequence:

>609_bases
ATGGTAGGCGCTGTGACCCAGATAGCGGATCGGCCTACAGACCCCTCGCCCTGGTCGCCGCGAGAGACCGAGTTACTGGC
GGTGACACTACGGCTGCTGCAGGAGCACGGTTATGACCGGCTAACAGTGGATGCCGTTGCGGCGAGCGCCCGCGCCAGCA
AGGCAACGGTCTACCGGCGCTGGCCGTCGAAAGCCGAATTGGTGCTGGCCGCGTTCATCGAGGGCATCCGCCAGGTCGCG
GTCCCGCCCAATACCGGCAACCTGCGCGACGACTTGCTGCGACTGGGGGAGCTGATCTGTCGGGAGGTGGGCCAACACGC
CAGCACCATCCGCGCGGTGCTCGTCGAAGTGTCGCGCAATCCTGCCCTCAACGACGTTTTGCAGCATCAGTTCGTCGACC
ACCGTAAGGCCCTGATCCAGTACATCTTGCAGCAGGCCGTCGACCGCGGTGAGATCTCCAGCGCGGCCATCAGCGATGAA
CTCTGGGACCTGCTACCCGGCTACCTCATCTTCCGGTCCATCATCCCCAACCGGCCGCCCACCCAGGACACGGTGCAAGC
CCTCGTCGACGACGTGATACTCCCCAGCCTCACCCGATCCACCGGTTGA

Upstream 100 bases:

>100_bases
GCGACGGCGGGTTGGATGTTGCTCACCATGTAAAGTCGCTGGCCGGGCGCTTTGGCCGCCGGCACGGTACGGTACGGACC
TGTACCACCACAACGGTTCT

Downstream 100 bases:

>100_bases
GTCAGCGGTGCGAATGGCTGGGCACCGTTGTGGTGTCCGGTCCCGTACCGTACTGTTGAATCCGCGGATCCCCGCCTGAG
GTACGGGGCGTGGTCGCGCC

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA
VPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDE
LWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG

Sequences:

>Translated_202_residues
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA
VPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDE
LWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG
>Mature_202_residues
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA
VPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDE
LWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1556_MYCTU (P67436)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   A70763
- RefSeq:   NP_216072.1
- RefSeq:   NP_336060.1
- ProteinModelPortal:   P67436
- SMR:   P67436
- EnsemblBacteria:   EBMYCT00000001510
- EnsemblBacteria:   EBMYCT00000072937
- GeneID:   886367
- GeneID:   924337
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1607
- KEGG:   mtu:Rv1556
- TIGR:   MT1607
- TubercuList:   Rv1556
- GeneTree:   EBGT00050000014690
- HOGENOM:   HBG699776
- OMA:   HHASTIR
- ProtClustDB:   CLSK791246
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.10.60
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 22330; Mature: 22330

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TQDTVQALVDDVILPSLTRSTG
CHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TQDTVQALVDDVILPSLTRSTG
CHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036