Click here to switch to the map view.

The map label for this gene is frdD

Identifier: 121637475

GI number: 121637475

Start: 1772894

End: 1773271

Strand: Direct

Name: frdD

Synonym: BCG_1606

Alternate gene names: 121637475

Gene position: 1772894-1773271 (Clockwise)

Preceding gene: 121637474

Following gene: 121637476

Centisome position: 40.53

GC content: 66.14

Gene sequence:

>378_bases
ATGACTCCCTCGACATCGGATGCCAGGTCGCGCCGACGCTCGGCGGAGCCCTTCCTGTGGCTGCTGTTCAGCGCCGGGGG
CATGGTCACCGCCCTGGTTGCGCCCGTCCTGCTGTTGCTGTTCGGACTCGCGTTTCCGCTCGGGTGGCTCGACGCGCCCG
ACCACGGGCACCTACTGGCGATGGTGCGCAACCCGATCACCAAGCTTGTTGTGCTGGTCCTGGTGGTACTGGCCCTGTTC
CATGCGGCGCACCGGTTCCGGTTCGTGCTCGACCATGGGCTGCAACTGGGCCGGTTCGACCGAGTGATCGCCCTGTGGTG
TTACGGCATGGCCGTGTTGGGCTCGGCGACGGCGGGTTGGATGTTGCTCACCATGTAA

Upstream 100 bases:

>100_bases
TTCAGGTTCGCGGCCGCCGGGTACCCGCTCGCGCGGTCCTTGCTGGGCACTACGCGGCATGGCTGGTGGTTTCGGTGATC
GTTGCCTGGATGGTGCTGTC

Downstream 100 bases:

>100_bases
AGTCGCTGGCCGGGCGCTTTGGCCGCCGGCACGGTACGGTACGGACCTGTACCACCACAACGGTTCTATGGTAGGCGCTG
TGACCCAGATAGCGGATCGG

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALF
HAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM

Sequences:

>Translated_125_residues
MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALF
HAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM
>Mature_124_residues
TPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALFH
AAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDD_MYCBO (P67644)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855232.1
- ProteinModelPortal:   P67644
- SMR:   P67644
- EnsemblBacteria:   EBMYCT00000014578
- GeneID:   1092450
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1580
- GeneTree:   EBGT00050000018577
- HOGENOM:   HBG127968
- OMA:   MRRSHEP
- ProtClustDB:   PRK05470
- BioCyc:   MBOV233413:MB1580-MONOMER
- HAMAP:   MF_00709
- InterPro:   IPR003418

Pfam domain/function: PF02313 Fumarate_red_D

EC number: 1.3.99.1

Molecular weight: Translated: 13754; Mature: 13623

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15986c04)-; HASH(0x15f0fb70)-; HASH(0x160a7cc0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLA
CCCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MVRNPITKLVVLVLVVLALFHAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCE
MLLTM
EEEEH
>Mature Secondary Structure 
TPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLA
CCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MVRNPITKLVVLVLVVLALFHAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCE
MLLTM
EEEEH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972