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The map label for this gene is mutB [H]

Identifier: 121637421

GI number: 121637421

Start: 1704015

End: 1704245

Strand: Direct

Name: mutB [H]

Synonym: BCG_1552

Alternate gene names: 121637421

Gene position: 1704015-1704245 (Clockwise)

Preceding gene: 121637420

Following gene: 121637422

Centisome position: 38.95

GC content: 68.83

Gene sequence:

>231_bases
GTGTCGGTCGGTGAGGTCGAGGTGCTCAAGGTCGAAAACAGCCGGGTGCGCGCCGAGCAGCTGGCCAAACTGTACGAATT
GCGCTCAAGTCGGGATCGGGTCAGGGTCGACGCCGCACTAGCCGAGCTGAGCCGCGCCGCGGCCGCCCGCGGTTGTGCCG
GTACTAGCGGGCTCGGCAACAACCTGATGGCGCCGGGGCCGCCCCATTCCCTCCTGGGACGGGATCGCTGA

Upstream 100 bases:

>100_bases
GATTCCGGCGGCGTCATTCCTGACGTTGTTCGCGCTGATGACGGCAAAGGGGCCGGAGCGCACTTAAGCATGGAGGCGCA
ACTCGACCTATGGCAGTGGT

Downstream 100 bases:

>100_bases
CGCCACAATCGACCTGCTACGAAGGCTGGCCGAGCGGCTGGGGTACACACTGGATTGGCGAGCGATCCGTGGAGCCGAAC
CCGTTGCCACCGCCATTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: MCM [H]

Number of amino acids: Translated: 76; Mature: 75

Protein sequence:

>76_residues
MSVGEVEVLKVENSRVRAEQLAKLYELRSSRDRVRVDAALAELSRAAAARGCAGTSGLGNNLMAPGPPHSLLGRDR

Sequences:

>Translated_76_residues
MSVGEVEVLKVENSRVRAEQLAKLYELRSSRDRVRVDAALAELSRAAAARGCAGTSGLGNNLMAPGPPHSLLGRDR
>Mature_75_residues
SVGEVEVLKVENSRVRAEQLAKLYELRSSRDRVRVDAALAELSRAAAARGCAGTSGLGNNLMAPGPPHSLLGRDR

Specific function: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates [H]

COG id: COG1884

COG function: function code I; Methylmalonyl-CoA mutase, N-terminal domain/subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: =5.4.99.2 [H]

Molecular weight: Translated: 8101; Mature: 7970

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGEVEVLKVENSRVRAEQLAKLYELRSSRDRVRVDAALAELSRAAAARGCAGTSGLGN
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NLMAPGPPHSLLGRDR
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVGEVEVLKVENSRVRAEQLAKLYELRSSRDRVRVDAALAELSRAAAARGCAGTSGLGN
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NLMAPGPPHSLLGRDR
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]