Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 121637285

GI number: 121637285

Start: 1546519

End: 1548390

Strand: Reverse

Name: yciR [C]

Synonym: BCG_1416c

Alternate gene names: 121637285

Gene position: 1548390-1546519 (Counterclockwise)

Preceding gene: 121637286

Following gene: 121637284

Centisome position: 35.4

GC content: 61.59

Gene sequence:

>1872_bases
ATGTGCAACGACACCGCGACGCCGCAGCTTGAGGAGCTCGTCACCACCGTAGCCAACCAGCTCATGACAGTCGACGCTGC
CACGTCAGCCGAAGTCAGTCAGCGCGTTTTGGCCTATCTAGTGGAACAGCTGGGCGTAGATGTCAGCTTTTTGCGTCATA
ACGATCGCGACAGGCGCGCGACGAGGCTGGTGGCCGAATGGCCACCTCGCCTCAACATACCGGACCCCGATCCGCTCAGG
CTGATCTACTTCGCTGATGCCGACCCGGTGTTTGCGCTATGCGAACACGCCAAAGAGCCTCTCGTGTTCCGGCCCGAGCC
GGCCACCGAGGACTATCAACGCCTCATCGAAGAAGCCCGCGGGGTTCCGGTAACGTCGGCTGCCGCCGTGCCGCTGGTAT
CTGGCGAGATCACCACTGGACTGCTGGGGTTCATCAAGTTCGGTGATCGGAAATGGCACGAGGCCGAGCTTAACGCCCTC
ATGACCATCGCTACACTCTTCGCCCAGGTGCAGGCTCGCGTCGCCGCCGAGGCGCGGCTTCGCTATCTGGCCGACCATGA
CGATCTGACCGGACTGCATAACCGTCGCGCGTTGCTGCAGCACCTGGACCAAAGACTGGCCCCCGGACAACCTGGCCCGG
TCGCGGCGCTATTTCTCGACTTGGACCGCCTCAAGGCCATCAACGACTACCTGGGCCACGCCGCCGGTGACCAGTTCATC
CATGTGTTCGCCCAACGGATCGGTGACGCACTCGTTGGCGAGAGCCTGATCGCCCGACTCGGCGGCGACGAATTCGTCCT
CATACCCGCATCTCCAATGAGTGCCGATGCCGCTCAACCGCTCGCCGAACGTCTTCGCGACCAGCTCAAGGACCACGTCG
CTATCGGCGGTGAGGTGCTCACCCGCACCGTCAGTATCGGTGTCGCCTCAGGGACTCCCGGACAGCACACACCGTCGGAC
CTCCTGCGCCGAGCCGACCAAGCCGCTCTGGCAGCCAAACACGCCGGCGGAGATAGCGTCGCGATTTTCACCGCGGACAT
GTCGGTCAGCGGCGAACTGCGCAACGATATTGAACTACACCTTCGACGTGGTATCGAATCCGACGCCCTTCGCCTGGTCT
ACCTACCCGAGGTCGACCTACGGACCGGCGACATTGTCGGGACCGAGGCATTGGTCCGGTGGCAGCACCCCACCCGTGGG
CTGCTGGCACCGGGCTGCTTCATCCCTGTGGCCGAATCCATCAACCTTGCAGGCGAATTGGATAGATGGGTGCTGCGGAG
GGCCTGCAATGAATTCTCCGAGTGGCAGTCAGCCGGTTTGGGCCACGACGCGCTGCTGCGTATCAACGTCTCAGCTGGAC
AGCTGGTGACGGGCGGGTTTGTTGACTTCGTCGCAGACACGATCGGCCAGCACGGTCTGGACGCCTCGTCCGTGTGTTTG
GAAATCACCGAAAACGTTGTGGTGCAAGACCTACATACCGCCAGAGCCACCCTGGCTCGACTCAAAGAAGTCGGCGTTCA
CATCGCTATCGACGATTTCGGCACCGGCTATAGCGCCATATCACTGTTGCAGACGCTACCGATCGACACGCTCAAGATCG
ACAAAACATTCGTGCGGCAACTCGGAACCAACACTAGCGATCTGGTCATTGTGCGCGGCATCATGACACTCGCCGAAGGC
TTCCAACTCGATGTAGTAGCCGAAGGCGTCGAGACCGAGGCTGCCGCCAGAATTCTATTGGATCAGCGCTGTTACCGTGC
GCAAGGCTTCTTGTTCTCCCGGCCTGTCCCCGGGGAGGCCATGCGGCACATGTTGTCCGCACGACGACTACCGCCGACCT
GCATACCTGCAACTGACCCGGCGTTATCTTGA

Upstream 100 bases:

>100_bases
AGGTGTTGATCTTCAGGTTGTTCCACGCGCCACCGCCGTCGGTGTGTAGCCGCCGACGCGTACGGCACGCCATACCAGAG
CCGCACAGATAGCATCCGAG

Downstream 100 bases:

>100_bases
TGGAGGTGCCGTAACGGCAATGCAGACAACCCCAGGCAAGCGTCAACGACGGCAGCGCGGATCCATCAACCCCGAGGACA
TCATCAGCGGCGCATTCGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLR
LIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNAL
MTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI
HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSD
LLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG
LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL
EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEG
FQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS

Sequences:

>Translated_623_residues
MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLR
LIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNAL
MTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI
HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSD
LLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG
LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL
EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEG
FQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS
>Mature_623_residues
MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLR
LIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNAL
MTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI
HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSD
LLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG
LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL
EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEG
FQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain

Homologues:

Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=32.6291079812207, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI87081921, Length=458, Percent_Identity=31.0043668122271, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI226510982, Length=414, Percent_Identity=29.7101449275362, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1787055, Length=458, Percent_Identity=29.2576419213974, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=32.9588014981273, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1790496, Length=253, Percent_Identity=30.8300395256917, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI87081743, Length=239, Percent_Identity=32.6359832635983, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788849, Length=253, Percent_Identity=31.2252964426877, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788502, Length=234, Percent_Identity=32.9059829059829, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=30.5555555555556, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87081845, Length=236, Percent_Identity=32.6271186440678, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=421, Percent_Identity=26.603325415677, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1787262, Length=231, Percent_Identity=27.7056277056277, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=38.3720930232558, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=255, Percent_Identity=29.0196078431373, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=34.4632768361582, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082007, Length=176, Percent_Identity=32.9545454545455, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI145693134, Length=196, Percent_Identity=29.5918367346939, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=127, Percent_Identity=39.3700787401575, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789650, Length=497, Percent_Identity=22.9376257545272, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=32.9113924050633, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=30.3370786516854, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=29.6774193548387, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=33.1288343558282, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1354_MYCTU (P64825)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   A70741
- RefSeq:   NP_215870.1
- RefSeq:   NP_335846.1
- ProteinModelPortal:   P64825
- EnsemblBacteria:   EBMYCT00000002669
- EnsemblBacteria:   EBMYCT00000072094
- GeneID:   886829
- GeneID:   924615
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1397
- KEGG:   mtu:Rv1354c
- TIGR:   MT1397
- TubercuList:   Rv1354c
- GeneTree:   EBGT00050000014822
- HOGENOM:   HBG751764
- OMA:   MENAANT
- ProtClustDB:   CLSK791118
- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- SMART:   SM00052
- SMART:   SM00065
- SMART:   SM00267
- TIGRFAMs:   TIGR00254

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; SSF55073 A/G_cyclase

EC number: NA

Molecular weight: Translated: 67654; Mature: 67654

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50883 EAL; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA
CCCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCEEEHHCCCCHHHH
TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR
HHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHC
GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL
CCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH
HHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHH
LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL
HHCCCCCCCEEEEEECCCCCCCCCEECCHHHEEECCCCCCCCCCCCHHHHHHHCCHHHHH
DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHCCCCHHHHHH
EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHH
LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA
HCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEECCCCCHHH
MRHMLSARRLPPTCIPATDPALS
HHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA
CCCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCEEEHHCCCCHHHH
TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR
HHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHC
GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL
CCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH
HHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHH
LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL
HHCCCCCCCEEEEEECCCCCCCCCEECCHHHEEECCCCCCCCCCCCHHHHHHHCCHHHHH
DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHCCCCHHHHHH
EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHH
LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA
HCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEECCCCCHHH
MRHMLSARRLPPTCIPATDPALS
HHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036