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The map label for this gene is 121637284

Identifier: 121637284

GI number: 121637284

Start: 1545714

End: 1546499

Strand: Reverse

Name: 121637284

Synonym: BCG_1415c

Alternate gene names: NA

Gene position: 1546499-1545714 (Counterclockwise)

Preceding gene: 121637285

Following gene: 121637278

Centisome position: 35.35

GC content: 62.6

Gene sequence:

>786_bases
ATGCAGACAACCCCAGGCAAGCGTCAACGACGGCAGCGCGGATCCATCAACCCCGAGGACATCATCAGCGGCGCATTCGA
ACTCGCCCAGCAGGTATCGATAGACAACTTGAGCATGCCATTGCTCGGCAAACACCTTGGCGTCGGGGTCACCAGCATCT
ACTGGTACTTCCGCAAGAAGGACGATCTGCTCAACGCGATGACCGACCGCGCTTTGAGCAAGTACGTGTTCGCTACCCCG
TACATCGAAGCCGGCGACTGGCGCGAAACGTTGCGCAATCATGCCCGCTCGATGCGGAAGACGTTCGCGGACAACCCCGT
ACTGTGCGATCTGATACTGATTCGAGCGGCGCTGTCCCCGAAAACGGCGCGGTTGGGCGCCCAAGAGATGGAGAAGGCCA
TCGCCAATCTGGTGACGGCGGGCCTGTCGCTCGAAGACGCTTTCGACATCTACTCGGCGGTTTCGGTCCACGTGCGCGGA
TCGGTGGTGCTAGATCGGCTCTCCCGCAAGAGCCAGTCGGCGGGCAGCGGACCATCCGCCATTGAACACCCCGTGGCCAT
CGATCCCGCGACGACTCCGCTGCTTGCTCACGCAACTGGGAGGGGGCATCGGATCGGGGCCCCCGATGAAACCAATTTCG
AATATGGTCTCGAATGCATCCTCGACCATGCTGGCCGGTTGATCGAACAAAGCTCGAAAGCCGCTGGTGAGGTCGCAGTG
CGCCGCCCCACGGCCACCGCCGATGCGCCTACGCCGGGCGCGCGGGCCAAAGCGGTGGCGCGTTGA

Upstream 100 bases:

>100_bases
GGGGAGGCCATGCGGCACATGTTGTCCGCACGACGACTACCGCCGACCTGCATACCTGCAACTGACCCGGCGTTATCTTG
ATGGAGGTGCCGTAACGGCA

Downstream 100 bases:

>100_bases
GGGCTTACTGCGCTTCCAGTTCCGGCACGTGGTAGGCCCGCGGCCGGTACCGGGTACGCCGGCCCCTATGAGATCCGCAT
CCAAAGCTTGCAGTTATGCG

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATP
YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRG
SVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
RRPTATADAPTPGARAKAVAR

Sequences:

>Translated_261_residues
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATP
YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRG
SVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
RRPTATADAPTPGARAKAVAR
>Mature_261_residues
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATP
YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRG
SVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
RRPTATADAPTPGARAKAVAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1353_MYCTU (P67434)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   H70740
- RefSeq:   NP_215869.1
- RefSeq:   NP_335845.1
- ProteinModelPortal:   P67434
- EnsemblBacteria:   EBMYCT00000002636
- EnsemblBacteria:   EBMYCT00000070329
- GeneID:   886827
- GeneID:   924620
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1396
- KEGG:   mtu:Rv1353c
- TIGR:   MT1396
- TubercuList:   Rv1353c
- GeneTree:   EBGT00050000014736
- HOGENOM:   HBG564814
- OMA:   GPRAIED
- ProtClustDB:   CLSK791117
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR004111
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.10.60
- Gene3D:   G3DSA:1.10.357.10

Pfam domain/function: PF02909 TetR_C; PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 28253; Mature: 28253

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHH
DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA
HHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
HCCCCEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEE
RRPTATADAPTPGARAKAVAR
ECCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHH
DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA
HHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
HCCCCEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEE
RRPTATADAPTPGARAKAVAR
ECCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036