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The map label for this gene is dinG

Identifier: 121637260

GI number: 121637260

Start: 1523709

End: 1525703

Strand: Reverse

Name: dinG

Synonym: BCG_1391c

Alternate gene names: 121637260

Gene position: 1525703-1523709 (Counterclockwise)

Preceding gene: 121637261

Following gene: 121637258

Centisome position: 34.88

GC content: 67.32

Gene sequence:

>1995_bases
GTGTCCGAGTCGGTATCCATGTCTGTGCCTGAGCTGCTTGCCATCGCCGTGGCGGCACTTGGCGGCACCCGGCGTCGCGG
CCAGCAAGAGATGGCCGCCGCGGTAGCGCATGCGTTTGAAACCGGTGAGCACTTGGTGGTCCAGGCCGGCACCGGAACCG
GCAAGTCGCTGGCGTATCTGGTTCCCGCGATCATCCGCGCTCTTTGCGACGACGCGCCGGTCGTGGTGTCGACGGCGACG
ATCGCTTTGCAACGTCAACTCGTCGATCGTGACCTGCCCCAGCTGGTAGATTCGCTCACCAATGCGCTCCCCCGCCGACC
GAAGTTCGCCCTGCTCAAAGGTCGACGGAACTACCTGTGCCTGAACAAGATCCACAACTCAGTCACAGCCAGTGACCATG
ACGACGAGCGGCCGCAGGAGGAGCTCTTCGACCCGGTGGCGGTCACCGCGCTGGGACGCGATGTGCAACGGCTAACCGCC
TGGGCTTCGACGACCGTGTCTGGTGATCGCGACGACCTTAAGCCCGGTGTGGGAGACCGATCCTGGTCGCAGGTCAGCGT
TTCGGCGCGGGAATGCCTCGGCGTGGCCCGCTGCCCGTTTGGCTCGGAGTGCTTCTCCGAACGGGCTCGTGGAGCGGCCG
GCCTGGCCGATGTCGTCGTCACCAACCACGCGCTGCTGGCCATCGATGCCGTCGCCGAATCGGCGGTACTGCCAGAACAT
CGGCTGCTGGTTGTCGACGAGGCTCACGAATTGGCCGACCGGGTGACCTCGGTAGCCGCCGCTGAGCTGACGTCTGCCAC
GCTCGGTATGGCCGCACGACGGATCACCCGGCTGGTCGACCCGAAAGTGACCCAGCGGCTTCAGGCGGCTTCGGCTACCT
TCAGTTCGGCGATTCACGACGCCAGACCGGGCCGCATTGATTGCCTCGATGACGAGATGGCGACCTATCTGAGCGCGCTG
CGCGATGCGGCCAGTGCGGCGCGCTCAGCGATCGATACCGGCAGCGACACCACGACGGCGTCCGTGCGCGCCGAAGCGGG
CGCGGTACTGACCGAAATATCCGATACCGCGTCACGAATCCTGGCGTCGTTCGCCCCCGCTATCCCTGACCGCAGCGACG
TGGTTTGGCTGGAGCACGAGGACAACCACGAATCGGCTCGCGCGGTGCTGCGGGTGGCTCCGCTATCGGTGGCCGAGCTG
TTGGCCACCCAGGTGTTCGCCCGTGCAACGACCGTATTGACCTCGGCAACGCTGACAATCGGCGGGTCGTTTGACGCGAT
GGCCACGGCATGGGGCCTGACTGCAGACACGCCCTGGCGTGGCCTGGACGTGGGCTCGCCTTTCCAGCACGCAAAGTCGG
GAATCCTCTACGTGGCCGCCCATCTCCCGCCGCCGGGCCGAGACGGCAGCGGCTCGGCCGAACAACTGACCGAGATCGCC
GAACTCATCACCGCTGCAGGTGGGCGCACCCTGGGGCTGTTCTCGTCCATGCGGGCCGCCCGGGCAGCCACCGAGGCCAT
GCGCGAACGGCTGTCCACGCCGGTGTTGTGTCAGGGCGACGACAGTACGTCCACGCTGGTGGAGAAGTTCACCGCCGATG
CGGCGACCTCCCTGTTCGGCACGCTGTCGCTGTGGCAGGGGGTCGACGTGCCGGGACCGTCGCTGTCGTTGGTGTTGATC
GACCGCATCCCGTTCCCCCGGCCGGACGATCCCCTGCTGAGTGCCCGCCAGCGTGCGGTGGCCGCCCGTGGCGGCAACGG
CTTCATGACGGTCGCCGCCAGCCACGCGGCGCTGCTGCTGGCACAGGGATCCGGCCGGCTGTTACGGCGCGTCACCGATC
GGGGCGTGGTTGCGGTGCTCGATTCACGGATGGCTACCGCCCGCTATGGCGAATTCCTGCGAGCCTCGCTGCCGCCCTTT
TGGCAGACCACCAACGCCACGCAAGTGCGCGCGGCCCTGCGGCGCCTTGCGCGAGCAGACGCAAAAGCCCACTAA

Upstream 100 bases:

>100_bases
TGCGCAGCCTGCCAGCCGACGGGCTGAAATTGGCACCCGGCGAGCCGGCGATTCCGACACGCACGATCCCGGCCTGAGCG
CAAGGATGTGACCACGTCCC

Downstream 100 bases:

>100_bases
ATCGGCCAGATTTAGGAGCTTTTGCGTCTTCTCGGCGGGTCAGGCCAGGGTGACCAGGCCGAGCTCGTTGCTGGCGGCCA
GCATCGGGTGGCGAGGCAGC

Product: putative atp-dependent helicase dinG-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYLVPAIIRALCDDAPVVVSTAT
IALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLCLNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTA
WASTTVSGDRDDLKPGVGDRSWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEH
RLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHDARPGRIDCLDDEMATYLSAL
RDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRILASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAEL
LATQVFARATTVLTSATLTIGGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIA
ELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFGTLSLWQGVDVPGPSLSLVLI
DRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLLAQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPF
WQTTNATQVRAALRRLARADAKAH

Sequences:

>Translated_664_residues
MSESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYLVPAIIRALCDDAPVVVSTAT
IALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLCLNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTA
WASTTVSGDRDDLKPGVGDRSWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEH
RLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHDARPGRIDCLDDEMATYLSAL
RDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRILASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAEL
LATQVFARATTVLTSATLTIGGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIA
ELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFGTLSLWQGVDVPGPSLSLVLI
DRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLLAQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPF
WQTTNATQVRAALRRLARADAKAH
>Mature_663_residues
SESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYLVPAIIRALCDDAPVVVSTATI
ALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLCLNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTAW
ASTTVSGDRDDLKPGVGDRSWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEHR
LLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHDARPGRIDCLDDEMATYLSALR
DAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRILASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAELL
ATQVFARATTVLTSATLTIGGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIAE
LITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFGTLSLWQGVDVPGPSLSLVLID
RIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLLAQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPFW
QTTNATQVRAALRRLARADAKAH

Specific function: Probable helicase involved in DNA repair and perhaps also replication

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain

Homologues:

Organism=Escherichia coli, GI1788110, Length=642, Percent_Identity=34.1121495327103, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1787018, Length=268, Percent_Identity=33.5820895522388, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DING_MYCBO (P64315)

Other databases:

- EMBL:   BX248338
- RefSeq:   NP_855018.1
- ProteinModelPortal:   P64315
- EnsemblBacteria:   EBMYCT00000017048
- GeneID:   1090657
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1364c
- GeneTree:   EBGT00050000016075
- HOGENOM:   HBG527643
- OMA:   RANYVCH
- ProtClustDB:   CLSK871926
- BioCyc:   MBOV233413:MB1364C-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014013
- InterPro:   IPR006555
- SMART:   SM00487
- SMART:   SM00491

Pfam domain/function: PF00270 DEAD

EC number: =3.6.4.12

Molecular weight: Translated: 70168; Mature: 70037

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00690 DEAH_ATP_HELICASE; PS51193 HELICASE_ATP_BIND_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYL
CCCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
VPAIIRALCDDAPVVVSTATIALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLC
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCEECCCCCEEE
LNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTAWASTTVSGDRDDLKPGVGDR
HHHHHCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
SWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEH
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHCCHHEEHHHHHHHHCCCCC
RLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHD
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHC
ARPGRIDCLDDEMATYLSALRDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCHHHHHHHHHHHHH
LASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAELLATQVFARATTVLTSATLTI
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEE
GGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIA
CCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
ELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
TLSLWQGVDVPGPSLSLVLIDRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLL
HHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEE
AQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPFWQTTNATQVRAALRRLARAD
ECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
AKAH
CCCC
>Mature Secondary Structure 
SESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYL
CCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
VPAIIRALCDDAPVVVSTATIALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLC
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCEECCCCCEEE
LNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTAWASTTVSGDRDDLKPGVGDR
HHHHHCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
SWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEH
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHCCHHEEHHHHHHHHCCCCC
RLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHD
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHC
ARPGRIDCLDDEMATYLSALRDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCHHHHHHHHHHHHH
LASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAELLATQVFARATTVLTSATLTI
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEE
GGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIA
CCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
ELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
TLSLWQGVDVPGPSLSLVLIDRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLL
HHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEE
AQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPFWQTTNATQVRAALRRLARAD
ECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
AKAH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972