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The map label for this gene is oppA [C]

Identifier: 121637208

GI number: 121637208

Start: 1458289

End: 1460064

Strand: Reverse

Name: oppA [C]

Synonym: BCG_1339c

Alternate gene names: 121637208

Gene position: 1460064-1458289 (Counterclockwise)

Preceding gene: 121637209

Following gene: 121637204

Centisome position: 33.38

GC content: 65.15

Gene sequence:

>1776_bases
GTGGCTGACCGTGGCCAGCGACGAGGCTGCGCCCCGGGCATCGCGTCTGCGCTCAGGGCGTCGTTTCAGGGGAAATCCAG
ACCCTGGACGCAGACTCGATATTGGGCTTTCGCGTTATTAACACCGCTCGTCGTGGCTATGGTGCTCACCGGATGCTCGG
CCTCCGGTACCCAACTCGAACTCGCGCCCACTGCGGACCGCAGGGCCGCGGTTGGCACCACCAGCGACATCAATCAGCAG
GATCCCGCCACGTTGCAAGACGGCGGCAATCTTCGCCTGTCGCTCACCGACTTTCCGCCCAACTTCAACATCTTGCACAT
CGACGGCAACAACGCCGAGGTCGCGGCGATGATGAAAGCCACCTTGCCGCGCGCGTTCATCATCGGACCGGACGGCTCGA
CGACGGTCGACACCAACTACTTCACCAGCATCGAGCTGACCAGGACCGCCCCGCAGGTGGTCACCTACACCATCAATCCC
GAGGCGGTGTGGTCCGACGGGACCCCGATCACCTGGCGGGACATCGCCAGCCAGATTCATGCGATCAGCGGCGCCGACAA
GGCATTCGAGATCGCTTCTAGCAGCGGCGCCGAGCGTGTGGCGTCGGTAACCAGAGGGGTCGACGACCGGCAGGCCGTGG
TGACGTTCGCCAAGCCGTACGCGGAGTGGCGCGGTATGTTCGCGGGCAACGGCATGCTGCTGCCGGCCAGTATGACCGCC
ACACCCGAGGCATTCAATAAGGGTCAACTCGATGGGCCCGGTCCGTCGGCGGGTCCGTTCGTCGTGTCTGCCCTGGACCG
CACCGCGCAGCGAATCGTGTTGACCCGTAACCCGAGATGGTGGGGGGCACGGCCACGCCTGGACAGCATCACATACCTGG
TGCTCGATGATGCCGCCCGGCTGCCGGCGCTGCAGAACAACACAATCGACGCCACCGGCGTCGGCACACTGGACCAGCTG
ACCATCGCGGCGCGCACCAAGGGCATCTCGATCCGGCGCGCCCCCGGGCCCAGCTGGTATCACTTCACCCTCAACGGTGC
GCCTGGGTCGATCCTCGCCGACAAGGCGCTGCGCCTGGCGATCGCCAAGGGCATCGACCGATACACCATCGCCAGGGTCG
CCCAATACGGCCTCACCAGCGACCCGGTGCCACTGAACAACCACGTCTTCGTCGCCGGCCAAGACGGCTACCAGGACAAC
AGCGGCGTTGTCGCCTACAACCCGGAACAAGCGAAACGGGAGCTGGACGCCCTGGGCTGGAGGCGAAGCGGCGCGTTCCG
GGAGAAGGACGGTCGCCAGCTCGTCATCCGCGATCTGTTCTACGACGCACAAAGCACCCGGCAGTTCGCCCAGATCGCCC
AACACACCCTGGCGCAGATCGGCGTCAAACTCGAACTTCAGGCCAAGTCCGGCAGCGGTTTCTTCAGCGACTACGTCAAC
GTGGGGGCTTTCGACATCGCACAGTTCGGCTGGGTGGGCGACGCGTTTCCGCTGTCATCGCTCACCCAGATCTACGCTTC
GGACGGGGAAAGCAACTTCGGCAAGATCGGTAGCCCGCAAATCGACGCCGCGATCGAGCGAACGCTGGCAGAACTCGATC
CCGGCAAGGCGAGGGCCTTGGCCAACCAGGTCGACGAGCTGATCTGGGCCGAAGGATTCAGCCTGCCGCTTACCCAGTCG
CCCGGCACCGTTGCGGTCCGCAGCACGCTGGCCAACTTCGGCGCGACGGGTCTGGCAGACCTGGACTACACCGCCATCGG
GTTCATGCGACGCTGA

Upstream 100 bases:

>100_bases
GTTGTTGAGCAGGGCGACAGTGAGGAGGTCTTCGGCAATCCGAAACACGAGTACACCAGGCGACTGCTGGGCGCGGTACC
GCAACCGGATCCGGCCCGTC

Downstream 100 bases:

>100_bases
GCCGGCGGCGACCAGCTCAGCTGCGGATTAAGTCGGCGGCCTTCTCCCCGATCAGCACCGACGGCGCATGCGTATGCCCA
CGAACCGTGCTGGGCATCAC

Product: putative periplasmic oligopeptide-binding lipoprotein oppA

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQ
DPATLQDGGNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTAPQVVTYTINP
EAVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTA
TPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWGARPRLDSITYLVLDDAARLPALQNNTIDATGVGTLDQL
TIAARTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDN
SGVVAYNPEQAKRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAKSGSGFFSDYVN
VGAFDIAQFGWVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQS
PGTVAVRSTLANFGATGLADLDYTAIGFMRR

Sequences:

>Translated_591_residues
MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQ
DPATLQDGGNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTAPQVVTYTINP
EAVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTA
TPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWGARPRLDSITYLVLDDAARLPALQNNTIDATGVGTLDQL
TIAARTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDN
SGVVAYNPEQAKRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAKSGSGFFSDYVN
VGAFDIAQFGWVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQS
PGTVAVRSTLANFGATGLADLDYTAIGFMRR
>Mature_590_residues
ADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLTGCSASGTQLELAPTADRRAAVGTTSDINQQD
PATLQDGGNLRLSLTDFPPNFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTAPQVVTYTINPE
AVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTAT
PEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWGARPRLDSITYLVLDDAARLPALQNNTIDATGVGTLDQLT
IAARTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNS
GVVAYNPEQAKRELDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAKSGSGFFSDYVNV
GAFDIAQFGWVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSP
GTVAVRSTLANFGATGLADLDYTAIGFMRR

Specific function: This Protein Is A Component Of The Oligopeptide Permease, A Binding Protein-Dependent Transport System, It Binds Peptides Up To Five Amino Acids Long With High Affinity. [C]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family

Homologues:

None

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): Y1280_MYCTU (P66771)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   H70755
- RefSeq:   NP_215796.1
- RefSeq:   NP_335764.1
- ProteinModelPortal:   P66771
- EnsemblBacteria:   EBMYCT00000000127
- EnsemblBacteria:   EBMYCT00000071404
- GeneID:   886985
- GeneID:   924750
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1317
- KEGG:   mtu:Rv1280c
- TIGR:   MT1317
- TubercuList:   Rv1280c
- GeneTree:   EBGT00050000016139
- HOGENOM:   HBG564824
- OMA:   HIDGNSA
- ProtClustDB:   CLSK791076
- InterPro:   IPR000914

Pfam domain/function: PF00496 SBP_bac_5

EC number: NA

Molecular weight: Translated: 63477; Mature: 63346

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x156bf94c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLTGCSASGTQLE
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPPNFNILHIDGNNAEVAAMMKA
EECCCCCCEECCCCCCCCCCCCCEECCCCCEEEEEECCCCCCEEEEEECCCCEEHHHHHH
TLPRAFIIGPDGSTTVDTNYFTSIELTRTAPQVVTYTINPEAVWSDGTPITWRDIASQIH
HCCEEEEECCCCCCEECCCEEEEEEEEECCCEEEEEEECCCEEECCCCCEEHHHHHHHHH
AISGADKAFEIASSSGAERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTA
HHCCCCHHHEECCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHCCEECCCCEEEECCCCC
TPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWGARPRLDSITYLVLDDAAR
CCHHCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEEEEEECHHH
LPALQNNTIDATGVGTLDQLTIAARTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLA
CCCCCCCCCCCCCCCCHHHEEEEEECCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHH
IAKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRELDALGW
HHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHCC
RRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAKSGSGFFSDYVN
CCCCCCCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHC
VGAFDIAQFGWVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKARAL
CCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ANQVDELIWAEGFSLPLTQSPGTVAVRSTLANFGATGLADLDYTAIGFMRR
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCH
>Mature Secondary Structure 
ADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLTGCSASGTQLE
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPPNFNILHIDGNNAEVAAMMKA
EECCCCCCEECCCCCCCCCCCCCEECCCCCEEEEEECCCCCCEEEEEECCCCEEHHHHHH
TLPRAFIIGPDGSTTVDTNYFTSIELTRTAPQVVTYTINPEAVWSDGTPITWRDIASQIH
HCCEEEEECCCCCCEECCCEEEEEEEEECCCEEEEEEECCCEEECCCCCEEHHHHHHHHH
AISGADKAFEIASSSGAERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTA
HHCCCCHHHEECCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHCCEECCCCEEEECCCCC
TPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWGARPRLDSITYLVLDDAAR
CCHHCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEEEEEECHHH
LPALQNNTIDATGVGTLDQLTIAARTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLA
CCCCCCCCCCCCCCCCHHHEEEEEECCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHH
IAKGIDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRELDALGW
HHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHCC
RRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAKSGSGFFSDYVN
CCCCCCCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHC
VGAFDIAQFGWVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKARAL
CCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ANQVDELIWAEGFSLPLTQSPGTVAVRSTLANFGATGLADLDYTAIGFMRR
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036