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The map label for this gene is echA10 [C]

Identifier: 121637075

GI number: 121637075

Start: 1300567

End: 1301373

Strand: Reverse

Name: echA10 [C]

Synonym: BCG_1204c

Alternate gene names: 121637075

Gene position: 1301373-1300567 (Counterclockwise)

Preceding gene: 121637080

Following gene: 121637074

Centisome position: 29.75

GC content: 67.29

Gene sequence:

>807_bases
ATGTCGAACTACCGGATCGACACTCGGACAATTGTCCCGGGTCTCGCCGTCACCCTGGCCGACGGGGTGCTGTCGGTGAC
CATCGATCGCCCGGAGAGTCTCAACTCGCTGACCAAGCCGGTGCTGGCAGGGATGGCCGACGCGATCGAGGGCGCGGCCA
CCGACCCACGGGTGAAGGTGGTGCGCCTCGGGGGCGCCGGTCGCGGCTTCAGCTCCGGAGGGGCAATCAGCGTTGACGAT
GTGTGGGCCAGTGGCCCGCCTACCGACACCGTCGCGGAGGCCAACCGCACGGTGCGTGCCATTGTGGCACTACCACAACC
GGTCGTTGCCGTCGTGCAGGGACCAACCGTCGGCTGTGGCGTCTCCCTGGCGCTCGCTTGTGACCTCGTATTGGCCTCCG
ACAATGCGTTTTTCATGCTCGCTCACACCAACGTGGGGTTGATGCCCGACGGCGGCGCGTCGGCGTTGGTTCAGGCCGCG
ATCGGCCGCATCCGCGCCATGCATATGGCGCTGCTGCCGGACCGGGTGCCGGCCGCCGAGGCCTTGTCCTGGGGCCTGGT
CAGCGCCGTCTATCCGGCCGCCGACTTCGATGCCGAGGTGGACAAGTTGATCTCACGGCTGTTGGCCGGCCCAGCGCTGG
CTATCGCCAAGACGAAGAACGCGATCAATGCGGCCACGCTCACCGAGTTGGCACCCACTCTCCTGCGCGAATTGGATGGC
CAGGCCCTCCTCCTGCGTACTGACGACTTCGCCGAGGGCGCAACGGCATTCCAGCAGCGCCGGACCCCCATGTTCACCGG
CCGTTGA

Upstream 100 bases:

>100_bases
TGTACCGGCCTTTCGTCTCCCATTGACGCCCTCGACGGCGTATCGACGAAGATCATGTCGCCGCAGCTCGGTGACGGCGT
CGTCGATTAGTGTTAACCAC

Downstream 100 bases:

>100_bases
GCGCTCTCGGCCCGCTAGCGGTCCCGCGACTGGGCCGCGTCGATGCCCGTGTACTCACCGATTACTCCAACTGCTGGTTG
GGCATGTTTGCGGAGCATCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDD
VWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAA
IGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDG
QALLLRTDDFAEGATAFQQRRTPMFTGR

Sequences:

>Translated_268_residues
MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDD
VWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAA
IGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDG
QALLLRTDDFAEGATAFQQRRTPMFTGR
>Mature_267_residues
SNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDDV
WASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAAI
GRIRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDGQ
ALLLRTDDFAEGATAFQQRRTPMFTGR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=28.5140562248996, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI260274832, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI45643119, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260275230, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4757968, Length=233, Percent_Identity=28.755364806867, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI49355787, Length=233, Percent_Identity=28.755364806867, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542718, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI25453481, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI51538573, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI70995211, Length=192, Percent_Identity=31.25, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4757966, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI51538581, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI221136756, Length=234, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221136753, Length=234, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221307494, Length=234, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI116235487, Length=193, Percent_Identity=30.0518134715026, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=35.0597609561753, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788597, Length=251, Percent_Identity=32.2709163346614, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=32.4324324324324, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=29.0697674418605, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=29.7959183673469, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25145438, Length=255, Percent_Identity=29.0196078431373, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535521, Length=201, Percent_Identity=27.363184079602, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=188, Percent_Identity=29.2553191489362, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=220, Percent_Identity=26.8181818181818, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=263, Percent_Identity=25.0950570342205, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=27.9835390946502, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=27.9835390946502, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24654903, Length=254, Percent_Identity=24.0157480314961, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920382, Length=191, Percent_Identity=27.2251308900524, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=25.3968253968254, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=22.0472440944882, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27649; Mature: 27518

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKV
CCCCCCCHHHCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VRLGGAGRGFSSGGAISVDDVWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCG
EEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCEEEEEECCCCEEEEECCCCCCCC
VSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAE
HHHHHHEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCC
QALLLRTDDFAEGATAFQQRRTPMFTGR
CEEEEECCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKV
CCCCCCHHHCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VRLGGAGRGFSSGGAISVDDVWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCG
EEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCEEEEEECCCCEEEEECCCCCCCC
VSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAE
HHHHHHEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCC
QALLLRTDDFAEGATAFQQRRTPMFTGR
CEEEEECCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA