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The map label for this gene is ppdK [H]

Identifier: 121637059

GI number: 121637059

Start: 1281347

End: 1282819

Strand: Reverse

Name: ppdK [H]

Synonym: BCG_1188c

Alternate gene names: 121637059

Gene position: 1282819-1281347 (Counterclockwise)

Preceding gene: 121637060

Following gene: 121637058

Centisome position: 29.32

GC content: 66.6

Gene sequence:

>1473_bases
ATGACTCGTATCACCCGAGCCAATGGTTGCCCCGACGGAACTCTCGAAAACGCCGTTGTGGCGCTGGACGGCGGCGCGAA
CTACCCACGCGAGATCCTGGGCAACAAAGGCCACGGCATCGACATGATGCGCCGGCACCATCTGCCGGTGCCGCCTGCAT
TCTGCATTACCACCGAGGTGGGCGTGCGCTATCTCGCCGCGCCCGAATCCACGATCGCCGCGATCTGGGATGACGTGCTG
GATCGGATGAGCTGGCTGGAAACAGAAACCTCGTGCACGTTCGGCCGTGGCCCGAATCCGCTGCTGGTCAGCGTGCGCTC
GGGAGCCACCCAGTCGATGCCCGGCATGATGGACACGATTCTGGACGTGGGCATGACCGACGCGGTCGAACGAGTACTTG
CCAGGCCGGGTGCCGCCGACTTCGCCCACGACACCAGACGGCGATTCACCAGCATGTATCGGCGCATCGTCGGCAGCGCC
GGTCCCATTACCGACGACCCGTATGCCCAGTTGCGCGCGAGCATCGAGGCGGTATTCGCCTCCTGGAACTCACCTCGCGC
CGTTGCCTATCGCGACCATCACGGCCTCGACGACCAAGGCGGTACGGCGGTGGTGGTGCAGGCGATGGTATTCGGCAACC
TCACCGCGAACTCGGGCGCCGGGGTGCTGTCCTCACGCAACCCGATCACCGGAGCCAACGAACCGTTCGGCGAATGGCTA
CCCGGCGGCCAAGGCGACGACGTGGTGTCCGGATTGGTCGCCGTCGCACCGATCACCGCCCTGCGCGACCAGCAGCCGGC
CGTCTACGACCAACTGATGGCGGCCGCCCGCAGTTTGGAGCGCATGGCAGGCGACGTCCAGGAGATCGAATTCACCGTGG
AGGACAGCCAGCTGTGGCTGCTGCAGACCCGCGGGGCGGAACGCTCGGCGCAGGCCGCCGTGCGACTGGCGCTGCAACTG
CATCACGAGGGACTCATCGACGACACCGAGACACTGCGCCGGGTGACTCCGACGCACATCGAGACTTTGCTACGGCCGTC
GCTGCAGCCGGAAACACGGTTGGCCGCACCGCTTTTGGCCAAGGGCCTGCCCGCTTGCCCGGGCGTGGTATCCGGGACCG
CCTACACCGAGGTGGACGAGGCGCTGGACGCTGCGGACCGGGGCGAGCCGGTCATCTTGGTGCGAGATCACACCAGACCG
GAGGACGTCATGGGCATGCTTGCCGCGCAAGGCATTGTCACCGAGGTGGGGGGTGCCGCCAGTCATGCGGCGGTGGTTAG
CCGCGAGCTCGGTCGAGTGGCCGTGGTGGGTTGCGGTCCCGGGGTCGCGGCGGCACTGGCCGGCAAGGAGATCACCGTCG
ACGGCTATGAAGGCGAAGTGCGCCAAGGCGTTCTGGCATTGTCTGCCTGGTCGGAAAGTGACACGCCGGAGTTGCGCGAG
CTGGCCGACATCGCGCAACGGATCAGTTCATGA

Upstream 100 bases:

>100_bases
CCAGACACAAGCTGAGTAGTCCGACCGCTGACCAAGGCGCCCCCTGTGGGCCCACAGTGGGCGGTCTGGCGTTGCCCATA
AGTAGCATCAAGGGGTGCCC

Downstream 100 bases:

>100_bases
GCGAGTTGACGGTACTGCAGGCCGTGCGGCTCAAGGGCCGGGTGATCACCACCGACCTGGCGCAGACCTTGGGTGAAGAC
CTTGCCGACGTCGCCGCGAC

Product: pyruvate phosphate dikinase

Products: NA

Alternate protein names: Pyruvate, orthophosphate dikinase [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MTRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVL
DRMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSA
GPITDDPYAQLRASIEAVFASWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWL
PGGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQL
HHEGLIDDTETLRRVTPTHIETLLRPSLQPETRLAAPLLAKGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRP
EDVMGMLAAQGIVTEVGGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELRE
LADIAQRISS

Sequences:

>Translated_490_residues
MTRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVL
DRMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSA
GPITDDPYAQLRASIEAVFASWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWL
PGGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQL
HHEGLIDDTETLRRVTPTHIETLLRPSLQPETRLAAPLLAKGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRP
EDVMGMLAAQGIVTEVGGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELRE
LADIAQRISS
>Mature_489_residues
TRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVLD
RMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSAG
PITDDPYAQLRASIEAVFASWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWLP
GGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLH
HEGLIDDTETLRRVTPTHIETLLRPSLQPETRLAAPLLAKGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPE
DVMGMLAAQGIVTEVGGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELREL
ADIAQRISS

Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=329, Percent_Identity=27.9635258358663, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR010121
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.1 [H]

Molecular weight: Translated: 52073; Mature: 51942

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCHHHHHHCCCCCCCHHEEEHHH
GVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTI
CCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHH
LDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSAGPITDDPYAQLRASIEAVFA
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWL
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
PGGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWL
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEECCEEEE
LQTRGAERSAQAAVRLALQLHHEGLIDDTETLRRVTPTHIETLLRPSLQPETRLAAPLLA
EEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
KGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCH
SHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELRE
HHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEECCCCHHHHCEEEEEECCCCCCHHHHH
LADIAQRISS
HHHHHHHHCC
>Mature Secondary Structure 
TRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEV
CCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCHHHHHHCCCCCCCHHEEEHHH
GVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTI
CCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHH
LDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSAGPITDDPYAQLRASIEAVFA
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWL
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
PGGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWL
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEECCEEEE
LQTRGAERSAQAAVRLALQLHHEGLIDDTETLRRVTPTHIETLLRPSLQPETRLAAPLLA
EEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
KGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCH
SHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELRE
HHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEECCCCHHHHCEEEEEECCCCCCHHHHH
LADIAQRISS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2176881; 6257292; 11695893; 11468288; 8610096; 9753432 [H]