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The map label for this gene is glpX

Identifier: 121637030

GI number: 121637030

Start: 1259012

End: 1259998

Strand: Reverse

Name: glpX

Synonym: BCG_1159c

Alternate gene names: 121637030

Gene position: 1259998-1259012 (Counterclockwise)

Preceding gene: 121637032

Following gene: 121637029

Centisome position: 28.8

GC content: 66.36

Gene sequence:

>987_bases
ATGGAGCTGGTCCGGGTGACCGAGGCCGGAGCCATGGCCGCGGGCCGCTGGGTAGGCCGCGGCGACAAGGAGGGCGGCGA
CGGCGCGGCGGTCGACGCGATGCGCGAACTGGTCAACTCGGTTTCCATGCGCGGGGTGGTGGTCATCGGCGAAGGCGAAA
AGGACCACGCACCAATGCTCTACAACGGCGAAGAAGTGGGCAACGGCGACGGACCGGAATGCGACTTTGCCGTCGACCCC
ATTGACGGCACCACGCTGATGAGCAAGGGCATGACCAACGCCATCTCGGTGCTGGCGGTAGCCGATCGCGGCACCATGTT
CGACCCGTCGGCGGTGTTCTACATGAACAAAATCGCCGTCGGCCCCGATGCCGCACACGTGCTGGATATCACCGCGCCGA
TCTCGGAAAACATCCGAGCGGTCGCCAAGGTCAAGGACCTGTCGGTGCGAGACATGACGGTGTGCATCCTGGACAGGCCG
CGGCACGCGCAACTCATCCACGACGTCCGCGCCACCGGGGCCCGGATCCGGCTGATCACCGATGGCGACGTCGCCGGCGC
GATCTCGGCGTGCCGACCGCACTCCGGCACCGACCTGCTAGCTGGGATCGGCGGCACCCCGGAGGGAATCATCGCCGCCG
CGGCGATCCGCTGCATGGGCGGGGCGATCCAGGCGCAGCTCGCCCCGCGCGACGACGCGGAACGCCGCAAGGCCCTAGAA
GCCGGTTACGACCTGAACCAGGTCTTGACCACCGAAGATCTGGTGTCCGGGGAAAACGTCTTCTTCTGCGCCACTGGGGT
CACCGACGGCGACCTGCTCAAGGGAGTGCGTTACTACCCCGGCGGCTGCACCACCCATTCGATCGTGATGCGCTCGAAGT
CCGGCACCGTCCGGATGATCGAGGCCTACCACCGGCTTTCAAAGCTCAACGAATACTCCGCGATCGACTTCACCGGCGAC
AGCAGCGCCGTGTACCCATTGCCCTAA

Upstream 100 bases:

>100_bases
GACAGCTGAGGGATCCGGTTCGTCGACGGCCGCGGTGGCCAGCCACGACCCGTCGCACACCAGGCCATCGCGCCGGGAAG
CCCCGGACCGCAACCTGGCC

Downstream 100 bases:

>100_bases
CACACCCACGACACACAAGGAACCCGATCAATGGCCGTTGACGCCGACAGCGCCAATTACCGCATCGAGCACGACACCAT
GGGCGAAGTCCGGGTGCCGG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDP
IDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRP
RHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALE
AGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD
SSAVYPLP

Sequences:

>Translated_328_residues
MELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDP
IDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRP
RHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALE
AGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD
SSAVYPLP
>Mature_328_residues
MELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDP
IDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRP
RHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALE
AGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD
SSAVYPLP

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family

Homologues:

Organism=Escherichia coli, GI1790360, Length=321, Percent_Identity=42.9906542056075, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1789298, Length=315, Percent_Identity=40, Blast_Score=230, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPX_MYCBO (Q7U0N5)

Other databases:

- EMBL:   BX248337
- RefSeq:   NP_854785.1
- ProteinModelPortal:   Q7U0N5
- EnsemblBacteria:   EBMYCT00000014721
- GeneID:   1090398
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1129c
- GeneTree:   EBGT00050000017201
- HOGENOM:   HBG284837
- OMA:   CVLDRPR
- ProtClustDB:   PRK09479
- BioCyc:   MBOV233413:MB1129C-MONOMER
- GO:   GO:0005737
- InterPro:   IPR004464
- PIRSF:   PIRSF004532
- TIGRFAMs:   TIGR00330

Pfam domain/function: PF03320 FBPase_glpX

EC number: =3.1.3.11

Molecular weight: Translated: 34582; Mature: 34582

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: BINDING 148-148 BINDING 239-239

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPML
CCEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEE
YNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAV
ECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCEEEEEEECCCCEECCCCEEEEEEEEC
GPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLIT
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEE
DGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALE
CCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
AGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMI
CCCCHHHHHCHHHHCCCCCEEEEECCCCCHHHHCCCEECCCCCCEEEEEEECCCCCCHHH
EAYHRLSKLNEYSAIDFTGDSSAVYPLP
HHHHHHHHCCCCCEEEECCCCCEECCCC
>Mature Secondary Structure
MELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPML
CCEEEEECCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEE
YNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAV
ECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCEEEEEEECCCCEECCCCEEEEEEEEC
GPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLIT
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEE
DGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALE
CCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
AGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMI
CCCCHHHHHCHHHHCCCCCEEEEECCCCCHHHHCCCEECCCCCCEEEEEEECCCCCCHHH
EAYHRLSKLNEYSAIDFTGDSSAVYPLP
HHHHHHHHCCCCCEEEECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972