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The map label for this gene is ychK [C]

Identifier: 121636992

GI number: 121636992

Start: 1216227

End: 1217309

Strand: Reverse

Name: ychK [C]

Synonym: BCG_1121c

Alternate gene names: 121636992

Gene position: 1217309-1216227 (Counterclockwise)

Preceding gene: 121636993

Following gene: 121636982

Centisome position: 27.83

GC content: 68.79

Gene sequence:

>1083_bases
ATGCCCGCACCAGCTGCCCTCCGGGTGCGAGGGTCGTCTTCGCCGCGCGTCGCACTGGCGCTCGGCAGCGGCGGCGCCCG
GGGTTACGCCCACATCGGAGTGATCCAGGCGCTGCGGGAGCGCGGCTATGACATCGTTGGGATCGCCGGCTCGTCGATGG
GCGCGGTGGTCGGTGGGGTGCATGCGGCCGGCCGACTCGACGAGTTCGCCCACTGGGCCAAGTCCCTGACGCAGCGCACC
ATCTTGCGGCTGCTGGATCCGTCTATTAGCGCGGCCGGCATCCTGCGGGCAGAAAAGATTCTCGACGCGGTGCGCGACAT
CGTCGGCCCGGTCGCCATCGAGCAGCTGCCGATCCCCTATACCGCGGTGGCCACCGACCTACTGGCCGGCAAGTCGGTGT
GGTTTCAGCGCGGCCCCCTCGACGCGGCGATCCGGGCGTCCATCGCCATACCCGGGGTGATCGCCCCACACGAAGTCGAC
GGACGCCTGCTGGCCGACGGCGGAATCCTGGATCCACTGCCGATGGCGCCGATCGCCGGGGTCAACGCCGACCTGACCAT
CGCGGTCAGCCTTAACGGCAGTGAGGCCGGCCCCGCTCGCGATGCGGAGCCCAACGTCACCGCCGAGTGGTTGAACCGCA
TGGTGCGCAGCACTTCCGCGCTGTTTGACGTCAGCGCCGCCCGGTCGCTGCTCGACCGGCCTACGGCGCGGGCGGTGCTG
AGTCGCTTCGGCGCGGCGGCCGCGGAATCGGATTCCTGGTCGCAAGCTCCGGAGATCGAGCAGCGTCCAGCCGGCCCACC
AGCTGACCGCGAGGAAGCCGCTGACACACCCGGGCTACCCAAAATGGGCAGTTTCGAGGTGATGAATCGGACGATCGATA
TCGCCCAATCCGCACTGGCGCGCCATACGCTGGCGGGCTATCCGGCCGACCTGCTGATCGAGGTACCGCGTTCAACGTGC
CGAAGCCTGGAATTTCACCGCGCGGTGGAGGTGATCGCCGTCGGCCGCGCGCTGGCCACCCAAGCCTTGGAAGCATTCGA
GATCGACGACGACGAATCTGCCGCTGCGACCATCGAGGGCTGA

Upstream 100 bases:

>100_bases
CCAACGCGGAATGCGGATAACGCTCGGCAATTGAGATCAGGGGTGCAAGAAACTAGTGGCCGGATCCCGATAAGGGCACC
TCGCCGAGCAGAATGAAAGC

Downstream 100 bases:

>100_bases
TCAAACGCCGAGCAGCCTGGCAACGGCTTGCGCTTCGCGGCGGCCCTGCTGACGTCCGGCCATCGCCGAGTTCACACGGC
AGAGCGGATCCAGCGGGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGVHAAGRLDEFAHWAKSLTQRT
ILRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVD
GRLLADGGILDPLPMAPIAGVNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVL
SRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTC
RSLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG

Sequences:

>Translated_360_residues
MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGVHAAGRLDEFAHWAKSLTQRT
ILRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVD
GRLLADGGILDPLPMAPIAGVNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVL
SRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTC
RSLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG
>Mature_359_residues
PAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGVHAAGRLDEFAHWAKSLTQRTI
LRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVDG
RLLADGGILDPLPMAPIAGVNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVLS
RFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTCR
SLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain

Homologues:

Organism=Homo sapiens, GI260656039, Length=202, Percent_Identity=30.6930693069307, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI260656041, Length=203, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI116256487, Length=203, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI260656037, Length=202, Percent_Identity=30.6930693069307, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI260656043, Length=203, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI148727335, Length=203, Percent_Identity=29.064039408867, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI148727290, Length=203, Percent_Identity=29.064039408867, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI226510936, Length=321, Percent_Identity=32.7102803738318, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71997299, Length=185, Percent_Identity=26.4864864864865, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997289, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323581, Length=209, Percent_Identity=30.622009569378, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28571388, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281376913, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1063_MYCTU (P67098)

Other databases:

- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   E70892
- RefSeq:   NP_215579.1
- RefSeq:   NP_335533.1
- ProteinModelPortal:   P67098
- EnsemblBacteria:   EBMYCT00000003694
- EnsemblBacteria:   EBMYCT00000071715
- GeneID:   887128
- GeneID:   925091
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1093
- KEGG:   mtu:Rv1063c
- TIGR:   MT1093
- TubercuList:   Rv1063c
- GeneTree:   EBGT00050000014787
- HOGENOM:   HBG729555
- OMA:   SSINIMQ
- ProtClustDB:   CLSK790928
- InterPro:   IPR016035
- InterPro:   IPR001423
- InterPro:   IPR002641

Pfam domain/function: PF01734 Patatin; SSF52151 Acyl_Trfase/lysoPlipase

EC number: NA

Molecular weight: Translated: 37523; Mature: 37392

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01237 UPF0028

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGV
CCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HAAGRLDEFAHWAKSLTQRTILRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVDGRLLADGGILDPLPMAPIAG
HHHHHHHHHCCHHHEECCCCCHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
VNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVL
CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALA
HHHCCHHCCCCCCCCCCCCHHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RHTLAGYPADLLIEVPRSTCRSLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG
HHHHCCCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
>Mature Secondary Structure 
PAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDIVGIAGSSMGAVVGGV
CCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HAAGRLDEFAHWAKSLTQRTILRLLDPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TAVATDLLAGKSVWFQRGPLDAAIRASIAIPGVIAPHEVDGRLLADGGILDPLPMAPIAG
HHHHHHHHHCCHHHEECCCCCHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
VNADLTIAVSLNGSEAGPARDAEPNVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVL
CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPGLPKMGSFEVMNRTIDIAQSALA
HHHCCHHCCCCCCCCCCCCHHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RHTLAGYPADLLIEVPRSTCRSLEFHRAVEVIAVGRALATQALEAFEIDDDESAAATIEG
HHHHCCCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036