Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 121636934

GI number: 121636934

Start: 1152711

End: 1154147

Strand: Reverse

Name: pabB [H]

Synonym: BCG_1062c

Alternate gene names: 121636934

Gene position: 1154147-1152711 (Counterclockwise)

Preceding gene: 121636936

Following gene: 121636933

Centisome position: 26.38

GC content: 69.03

Gene sequence:

>1437_bases
TTGGCATTGGCTGCTCGCACAGCAACACCCCCCGGGACGGAGACCGGAGCCGGTCACGGATCGAACTTAGCGTGGGAGCT
TAGCACGCGGACGAAATCCCCACGCAGCCACTTGCGCTGCGAAAATCCACAGTTCTGTCAAGCTAGAACGGTGCGAATCG
ACCGACTCGGCGATCTTGGCGGAGCGCCTGCGGTGCTGCGGGCGGTCGGCCGCGCCACCAGTCGACTCGACTTGCCACCA
CCGGCGGCGCTGACCGGCGAATGGTTCGGTGCGCTGGCGGTGATCGCACCGAGTGTGTCTATACAACCGGTCAGCGGCGA
CGACGTGTTCTCGGGCCCGCCGGGCACCGGCGGGCCCGATGCCACCGGGGCGGTGGGCGGCGGCTGGGTCGGCTACCTGT
CCTACCCGGACGCCGGCGCCGACGGGCGACCCCACCGGATCCCCGAGGCCGCCGGCGGCTGGACCGATTGCGTGCTGCGC
CGCGACCGCGACGGCCAGTGGTGGTATGAGAGCCTGTCCGGTGCGCCGATAGCGGACTGGCTGGCCAGCGCGTTGGCGAC
CACTCGGGCATCGGTCGCCAGACCGGCACCGGCATGCCGGATCGACTGGGAACCGGCCGACCGGGCAGCGCACCGCGACG
GGGTACTGGCGTGTCTGGAAGCTATCGGCGCGGGCGAGGTCTATCAAGCGTGCGTGTGCACCCAATTCGCCGGGACGGTC
ACCGGATCCCCGCTGGACTTCTTCATCGACGGGTTCGGTCGTACCGCTCCGTCCCGGTCCGCCTTTGTCGCCGGACCGTG
GGGAGCCGTCGCATCGCTATCCCCGGAGCTATTCCTGCGCCGCCGCGGGTCCGTGGTGACATCGAGCCCGATCAAGGGCA
CGCTGCCGCTGGACGCCCCGCCGTCGGCGCTGCGGGCATCGGCCAAAGAGGTGGCCGAGAACATCATGATCGTGGATCTG
GTCCGCAACGACCTCGGCCGGGTAGCGGTTACCGGTACCGTGACGGTGCCCGAGCTGTTGGTGGTGCGACCAGCGCCGGG
AGTGTGGCACCTGGTGTCCACGGTGTCGGCGCGGGTTCCGCTCGAGGAACCGATGTCAGCGCTGCTCGACGCCGCCTTCC
CGCCGGCCTCGGTCACCGGCACACCTAAACTGCGGGCTCGCCAATTGATTTCACAATGGGAGCGATATCGCCGCGGGATA
TATTGCGGCACAGTCGGTTTGGCGTCACCGGTCGCCGGATGCGAGCTCAACGTCGCAATCCGCACCGTCGAATTCGATAC
CGCAGGCAACGCCGTGCTGGGCGTTGGCGGCGGGATCACCGCCGACTCCGATCCGGACGCCGAATGGGCGGAGTGCCTGC
ACAAAGCCGCTCCCATCGTCGGGCTGCCGGCCGCCACGCGCACCACCCCGGCTCGGTTAGCCAGCAAAGTGCGGTAG

Upstream 100 bases:

>100_bases
GCACACGACAACGCCGAGCGTGCTTTTCCTACTTCTTAAAACCATCGCTACTTCAAGATCACACCGAGCGTCAACGTCTC
GCGGTCAGCGAGAAACGGCA

Downstream 100 bases:

>100_bases
CCCAGCGGGCGGCGGAAATTGGCATAACGCCCACATGGTGTGCCGGGTGCGCCTAAGCTCGGGCCATCGACGCGTGTCTA
TCTCGTGTCGAGTTCGAGAG

Product: aminodeoxychorismate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MALAARTATPPGTETGAGHGSNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPP
PAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLR
RDRDGQWWYESLSGAPIADWLASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTV
TGSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDL
VRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGI
YCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR

Sequences:

>Translated_478_residues
MALAARTATPPGTETGAGHGSNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPP
PAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLR
RDRDGQWWYESLSGAPIADWLASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTV
TGSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDL
VRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGI
YCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR
>Mature_477_residues
ALAARTATPPGTETGAGHGSNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPPP
AALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLRR
DRDGQWWYESLSGAPIADWLASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVT
GSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDLV
RNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGIY
CGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=267, Percent_Identity=40.0749063670412, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI1787518, Length=266, Percent_Identity=30.0751879699248, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082077, Length=192, Percent_Identity=31.25, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=226, Percent_Identity=35.3982300884956, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324361, Length=286, Percent_Identity=28.6713286713287, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49704; Mature: 49573

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAARTATPPGTETGAGHGSNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLG
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCHHEEEEECCCCCC
GAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPD
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
ATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADW
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCHHHHHCCCCCHHHH
LASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTV
HHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
TGSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAP
CCCCHHHHHHCCCCCCCCCCEEEECCCCHHHHCCHHHHHHHCCCEEECCCCCCCCCCCCC
PSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVP
HHHHHHHHHHHHHCCEEEEEHHCCCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHHCCC
LEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCCEEEEEE
RTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR
EEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
ALAARTATPPGTETGAGHGSNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLG
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCHHEEEEECCCCCC
GAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPD
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
ATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADW
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCHHHHHCCCCCHHHH
LASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTV
HHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
TGSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAP
CCCCHHHHHHCCCCCCCCCCEEEECCCCHHHHCCHHHHHHHCCCEEECCCCCCCCCCCCC
PSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVP
HHHHHHHHHHHHHCCEEEEEHHCCCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHHCCC
LEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCCEEEEEE
RTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR
EEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]