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The map label for this gene is ompA [C]

Identifier: 121636822

GI number: 121636822

Start: 1033286

End: 1034266

Strand: Direct

Name: ompA [C]

Synonym: BCG_0951

Alternate gene names: 121636822

Gene position: 1033286-1034266 (Clockwise)

Preceding gene: 121636819

Following gene: 121636823

Centisome position: 23.62

GC content: 60.75

Gene sequence:

>981_bases
GTGGCTTCTAAGGCGGGTTTGGGCCAAACACCCGCGACCACCGACGCGCGACGAACTCAGAAATTCTACCGGGGCTCGCC
GGGCCGTCCGTGGCTGATTGGCGCGGTGGTTATTCCGTTGCTGATAGCGGCAATCGGTTACGGTGCATTCGAGCGGCCCC
AGTCCGTTACCGGACCGACCGGTGTGTTGCCGACACTGACACCGACCAGCACCCGGGGCGCTTCTGCGTTGTCCTTGTCT
TTGCTGTCAATTAGCCGCAGCGGCAACACCGTTACTCTGATCGGTGACTTCCCCGATGAGGCCGCCAAGGCGGCCTTGAT
GACGGCGCTCAACGGCTTGCTTGCTCCGGGCGTGAACGTCATCGACCAGATTCACGTCGATCCCGTTGTGCGATCACTTG
ATTTCTCAAGTGCGGAACCAGTTTTCACCGCCAGCGTGCCGATTCCTGATTTTGGCCTCAAAGTCGAAAGGGACACCGTC
ACCTTGACCGGAACTGCCCCTTCATCCGAGCACAAGGACGCAGTGAAGCGCGCGGCGACCAGCACCTGGCCTGACATGAA
AATCGTTAACAATATTGAGGTTACGGGGCAGGCACCGCCAGGACCCCCGGCCTCCGGCCCATGTGCCGACCTGCAATCAG
CCATCAATGCCGTGACGGGTGGACCCATCGCGTTTGGCAACGACGGGGCTAGTCTGATCCCAGCCGACTATGAAATCCTG
AACCGGGTAGCCGACAAGCTCAAGGCATGTCCGGACGCTCGGGTGACGATCAACGGCTACACCGACAACACCGGCAGCGA
AGGTATCAATATCCCGTTGAGCGCTCAGCGAGCCAAGATAGTCGCCGACTACCTGGTTGCCCGCGGAGTTGCCGGCGATC
ACATTGCCACCGTGGGTCTCGGTTCGGTGAATCCGATCGCCAGCAACGCCACACCCGAGGGGCGCGCCAAGAATCGTCGC
GTCGAGATCGTGGTCAACTAA

Upstream 100 bases:

>100_bases
GTGTGCCCGATTTGACGCGGTGTCCCGGCACCGACTCGGTAGGCTGCATATCGCCTGCAGCACGGACGAGACGCGTTCGA
CGACCTGAGGGAGTGGCGTA

Downstream 100 bases:

>100_bases
GGAGAACCCAGCATGGATTTTGTGATCCAGTGGTCGTGCTACCTGCTGGCGTTCCTGGGGGGCTCGGCTGTTGCCTGGGT
AGTCGTCACTCTGTCGATCA

Product: putative outer membrane protein A ompA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLS
LLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTV
TLTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEIL
NRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRR
VEIVVN

Sequences:

>Translated_326_residues
MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLS
LLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTV
TLTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEIL
NRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRR
VEIVVN
>Mature_325_residues
ASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLSL
LSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVT
LTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEILN
RVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRRV
EIVVN

Specific function: Unknown

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain

Homologues:

Organism=Escherichia coli, GI48994946, Length=104, Percent_Identity=48.0769230769231, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788957, Length=104, Percent_Identity=37.5, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787191, Length=114, Percent_Identity=32.4561403508772, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y899_MYCTU (P65593)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   H70782
- RefSeq:   NP_215414.1
- RefSeq:   NP_335355.1
- PDB:   2KGS
- PDB:   2KGW
- PDB:   2KSM
- PDBsum:   2KGS
- PDBsum:   2KGW
- PDBsum:   2KSM
- ProteinModelPortal:   P65593
- SMR:   P65593
- EnsemblBacteria:   EBMYCT00000001562
- EnsemblBacteria:   EBMYCT00000069816
- GeneID:   885286
- GeneID:   926237
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0922
- KEGG:   mtu:Rv0899
- TIGR:   MT0922
- TubercuList:   Rv0899
- GeneTree:   EBGT00050000018371
- HOGENOM:   HBG565454
- OMA:   VERDTIT
- ProtClustDB:   CLSK790818
- GO:   GO:0005829
- InterPro:   IPR001035
- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665
- InterPro:   IPR007055
- Gene3D:   G3DSA:3.30.1330.60
- PRINTS:   PR01023
- PRINTS:   PR01021

Pfam domain/function: PF04972 BON; PF00691 OmpA; SSF103088 OmpA/MotB_C

EC number: NA

Molecular weight: Translated: 33574; Mature: 33443

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS01068 OMPA_1; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x130d8494)-; HASH(0x142686c8)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPT
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVLPTLTPTSTRGASALSLSLLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNV
CCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHH
IDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVTLTGTAPSSEHKDAVKRAAT
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHH
STWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEIL
CCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCEECCCCHHHH
NRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGL
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
GSVNPIASNATPEGRAKNRRVEIVVN
CCCCCCCCCCCCCCCCCCCEEEEEEH
>Mature Secondary Structure 
ASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPT
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVLPTLTPTSTRGASALSLSLLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNV
CCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHH
IDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVTLTGTAPSSEHKDAVKRAAT
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHH
STWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEIL
CCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCEECCCCHHHH
NRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGL
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
GSVNPIASNATPEGRAKNRRVEIVVN
CCCCCCCCCCCCCCCCCCCEEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036