Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 121636548

GI number: 121636548

Start: 750891

End: 752618

Strand: Reverse

Name: recD [H]

Synonym: BCG_0675c

Alternate gene names: 121636548

Gene position: 752618-750891 (Counterclockwise)

Preceding gene: 121636549

Following gene: 121636547

Centisome position: 17.2

GC content: 69.97

Gene sequence:

>1728_bases
GTGAAGCTCACCGACGTCGATTTTGCCGTCGAGGCCTCCGGGATGGTGCGGGCCTTCAACCAGGCCGGTGTGCTGGACGT
GTCGGATGTGCATGTGGCGCAACGTCTCTGTGCACTGGCCGGGGAGAGCGACGAGCGGGTGGCGTTGGCGGTAGCGGTGG
CGGTCCGCGCGCTACGGGCCGGTTCGGTGTGTGTGGATCTGTTGTCGATCGCGCGGGTTGCTGGACACGACGACCTGCCG
TGGCCGGATCCGGCGGACTGGTTGGCGGCGGTGCGGGCCAGTCCGTTGCTCGCCGATCCACCCGTGCTGCACCTGTATGA
CGATCGGCTGCTCTATCTGGACCGCTACTGGCGCGAAGAAGAGCAGGTGTGCGCGGACCTGCTCGCGTTGCTGACATCCA
GGCGACCGGCCGGGGTACCCGACTTGCGGCGACTGTTCCCGACCGGCTTTGACGAGCAGCGGCGCGCGGCGGAAATCGCG
CTCTCGCAAGGTGTTACGGTGTTGACTGGCGGGCCTGGCACCGGAAAGACGACGACGGTCGCGCGGCTGCTGGCGTTGGT
TGCCGAGCAGGCGGAGCTGGCCGGTGAGCCGCGGCCGCGGATCGCGCTGGCCGCACCCACCGGCAAGGCGGCGGCCCGGC
TGGCCGAGGCGGTACGGCGCGAGATGGCCAAGCTCGACGCCACCGACCGGGCACGGCTCGGCGACCTGCACGCGGTCACG
CTGCATCGTCTGCTGGGTGCCAAACCGGGAGCGCGGTTTCGCCAGGATCGCCAGAACCGGTTGCCTCACAACGTGATCGT
GGTCGACGAGACCTCGATGGTGTCGCTGACGCTGATGGCCCGGCTGGCCGAGGCGGTGCGCCCGGGCGCCCGGTTGATCC
TCGTCGGCGATGCCGACCAGTTGGCGTCGGTGGAAGCCGGAGCGGTGCTGGCGGATTTGGTCGATGGCTTCTCGGTACGC
GACGACGCGCTGGTGGCGCAGCTGCGAACGTCGCATCGGTTCGGCAAGGTGATCGGTACCTTGGCCGAAGCGATCCGGGC
CGGCGATGGCGATGCCGTACTGGGCCTGCTGCGCTCGGGTGAGGAGCGGATCGAGTTCGTCGACGACGAGGATCCGGCGC
CGCGGTTGCGCGCGGTGCTGGTGCCACACGCGTTGCGGCTGCGCGAGGCGGCGCTGTTGGGTGCCTCCGACGTCGCGTTG
GCCACCCTGGACGAGCACCGGCTGCTGTGTGCGCATCGGGACGGGCCCACCGGCGTGCTGCACTGGAACCGCCGGGTTCA
AGCCTGGCTCGCCGAGGAGACCGGCCAGCCGCCCTGGACGCCGTGGTACGCCGGGCGTCCGCTGCTGGTGACGGCCAACG
ACTACGGCCTTCGCGTCTACAACGGCGACACCGGTGTCGTGCTGGCCGGCCCCACCGGTCTGCGGGCCGTCATTTCTGGT
GCATCCGGGCCACTTGACGTTGCCACCGGCCGCCTCGGCGACGTCGAGACCATGCACGCGATGACCATCCACAAGAGTCA
GGGCAGCCAGGTCGACGAGGTGACGGTGCTGATGCCGCAAGAGGATTCGCGGTTGCTGACCCGGGAGTTGCTGTACACCG
CGGTGGCCCGGGCCAAACGCAAGGTCCGGGTGGTCGGGTCCGAAGCTTCGGTGCGGGCCGCGATCGCACGCCGGGCGGTG
CGGGCCAGCGGGTTGCGGATGCGGTTACAGTCGACGGGGTGTGGCTGA

Upstream 100 bases:

>100_bases
CGGTGACGGCCGGGCATCCGGCCGGTGTGTTCACCTGGAACCCGCCCACGGCGTTGGTGGTGGCGCTCTCGGATCTGCTC
GACCGGGGAAGGCTGCAGTC

Downstream 100 bases:

>100_bases
CTCGTCGGGGATGTGCTCGGCTCGTCGGGTAACCGCGCCCGGACTTTGACATCGCATACACGAACAGCACGGCGACGGCG
CATCATGGATGTGTGCGGAT

Product: putative exonuclease V (alpha chain) recD

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHDDLP
WPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREEEQVCADLLALLTSRRPAGVPDLRRLFPTGFDEQRRAAEIA
LSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEPRPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGDLHAVT
LHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMARLAEAVRPGARLILVGDADQLASVEAGAVLADLVDGFSVR
DDALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVAL
ATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISG
ASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKRKVRVVGSEASVRAAIARRAV
RASGLRMRLQSTGCG

Sequences:

>Translated_575_residues
MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHDDLP
WPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREEEQVCADLLALLTSRRPAGVPDLRRLFPTGFDEQRRAAEIA
LSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEPRPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGDLHAVT
LHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMARLAEAVRPGARLILVGDADQLASVEAGAVLADLVDGFSVR
DDALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVAL
ATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISG
ASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKRKVRVVGSEASVRAAIARRAV
RASGLRMRLQSTGCG
>Mature_575_residues
MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHDDLP
WPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREEEQVCADLLALLTSRRPAGVPDLRRLFPTGFDEQRRAAEIA
LSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEPRPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGDLHAVT
LHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMARLAEAVRPGARLILVGDADQLASVEAGAVLADLVDGFSVR
DDALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVAL
ATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISG
ASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKRKVRVVGSEASVRAAIARRAV
RASGLRMRLQSTGCG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=581, Percent_Identity=36.4888123924269, Blast_Score=248, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 61718; Mature: 61718

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRA
CCCCCCCEEEECCHHHHHHCCCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GSVCVDLLSIARVAGHDDLPWPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREE
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCEEEEHHHHHCCH
EQVCADLLALLTSRRPAGVPDLRRLFPTGFDEQRRAAEIALSQGVTVLTGGPGTGKTTTV
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHH
ARLLALVAEQAELAGEPRPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGDLHAVT
HHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHH
LHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMARLAEAVRPGARLILVGDADQ
HHHHHCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCHH
LASVEAGAVLADLVDGFSVRDDALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
EERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVL
CHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCEEE
HWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISG
EECHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCHHHHHCC
ASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKR
CCCCCCCCCCCCCCCHHHHEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
KVRVVGSEASVRAAIARRAVRASGLRMRLQSTGCG
EEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRA
CCCCCCCEEEECCHHHHHHCCCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GSVCVDLLSIARVAGHDDLPWPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREE
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCEEEEHHHHHCCH
EQVCADLLALLTSRRPAGVPDLRRLFPTGFDEQRRAAEIALSQGVTVLTGGPGTGKTTTV
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHH
ARLLALVAEQAELAGEPRPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGDLHAVT
HHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHH
LHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMARLAEAVRPGARLILVGDADQ
HHHHHCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCHH
LASVEAGAVLADLVDGFSVRDDALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
EERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVL
CHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCEEE
HWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISG
EECHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCHHHHHCC
ASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKR
CCCCCCCCCCCCCCCHHHHEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
KVRVVGSEASVRAAIARRAVRASGLRMRLQSTGCG
EEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]