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The map label for this gene is csgA [H]

Identifier: 120613003

GI number: 120613003

Start: 4852829

End: 4853515

Strand: Reverse

Name: csgA [H]

Synonym: Aave_4367

Alternate gene names: 120613003

Gene position: 4853515-4852829 (Counterclockwise)

Preceding gene: 120613004

Following gene: 120613002

Centisome position: 90.67

GC content: 71.32

Gene sequence:

>687_bases
GTGTCGGAGGAGCGCTCCAGCCATCCGGTGCTGGTCATCGGGGCTTCCCGGGGCATCGGCCTGGAGTTCGTGCGCCAGTA
CCGCGAGGCGGGGCGGCGCGTGATCGCGACGGTGCGCGACGAGGCCGGGCGCGCACGCGTGAGTGCGCTGGGAGCCGAAG
TGCTGACGGTGGACGTGGCCCGGCCGGCCAGCGTGAGCGGCCTGGCCTGGCAGCTCGACGGCGAGAAGATCGGCCTGGCG
CTGTATGTCGCCGGCGTGATCCGCCGCCCTGGAGCACTCACGCCGCCGACGCAGGAGGATTTCGATGCGGTGATGCATAC
CAACGTGCTCGGCGCGATGCAGGCGCTGCCACAGGTGGCGCCCCTGGTGGCGGAGGCCCGTGGCGTGTTCGCGTTCCTCT
CGTCCTCGATGTCGCTGATCGGTGGTGTGCCCAACAGCGGGTCGTGGCTGTACCGCACGAGCAAGGCCGCGCTGAACATG
GCCGTGGCGGCCGCGCAGCACGACTATCCCTGGGCGACGCTCGTCACGCTGGATCCGGGCTGGGTGCGGACGGACATGGG
TGGGGCGGGAGGCGCGCTGGAGGTGACGGAGAGCGTGGAGCGCATGCGGGCCGTGCTGGAGGGGGTCACCCCGAATGACC
GGGGGCGGTTGCTGCACCACGATGGAAGAAGGGCGGCGCAATGGTGA

Upstream 100 bases:

>100_bases
ATGCCTTGAAGGCCCGTGGCAAGCGGCGCGGGCTGGCCACGCTGTGCATCGGCGGTGGCGAAGGCACGGCCATGGCGATC
GAACTGGTGTGAGCGCTGCC

Downstream 100 bases:

>100_bases
ACGCCGCCCGCGCAGGGATGGTCGGGGTGGCCGTGTGAGCGTGCCGGTGTCCCATGGGGACAATCGCTTCAATCTGCTCC
GGCTGGCGGCTGCCGTCGCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSEERSSHPVLVIGASRGIGLEFVRQYREAGRRVIATVRDEAGRARVSALGAEVLTVDVARPASVSGLAWQLDGEKIGLA
LYVAGVIRRPGALTPPTQEDFDAVMHTNVLGAMQALPQVAPLVAEARGVFAFLSSSMSLIGGVPNSGSWLYRTSKAALNM
AVAAAQHDYPWATLVTLDPGWVRTDMGGAGGALEVTESVERMRAVLEGVTPNDRGRLLHHDGRRAAQW

Sequences:

>Translated_228_residues
MSEERSSHPVLVIGASRGIGLEFVRQYREAGRRVIATVRDEAGRARVSALGAEVLTVDVARPASVSGLAWQLDGEKIGLA
LYVAGVIRRPGALTPPTQEDFDAVMHTNVLGAMQALPQVAPLVAEARGVFAFLSSSMSLIGGVPNSGSWLYRTSKAALNM
AVAAAQHDYPWATLVTLDPGWVRTDMGGAGGALEVTESVERMRAVLEGVTPNDRGRLLHHDGRRAAQW
>Mature_227_residues
SEERSSHPVLVIGASRGIGLEFVRQYREAGRRVIATVRDEAGRARVSALGAEVLTVDVARPASVSGLAWQLDGEKIGLAL
YVAGVIRRPGALTPPTQEDFDAVMHTNVLGAMQALPQVAPLVAEARGVFAFLSSSMSLIGGVPNSGSWLYRTSKAALNMA
VAAAQHDYPWATLVTLDPGWVRTDMGGAGGALEVTESVERMRAVLEGVTPNDRGRLLHHDGRRAAQW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558990, Length=246, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640547, Length=241, Percent_Identity=23.6514522821577, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 24291; Mature: 24160

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEERSSHPVLVIGASRGIGLEFVRQYREAGRRVIATVRDEAGRARVSALGAEVLTVDVA
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCHHEEEHHHHCCCHHHHHHHCCEEEEEECC
RPASVSGLAWQLDGEKIGLALYVAGVIRRPGALTPPTQEDFDAVMHTNVLGAMQALPQVA
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PLVAEARGVFAFLSSSMSLIGGVPNSGSWLYRTSKAALNMAVAAAQHDYPWATLVTLDPG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEEECCC
WVRTDMGGAGGALEVTESVERMRAVLEGVTPNDRGRLLHHDGRRAAQW
EEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
SEERSSHPVLVIGASRGIGLEFVRQYREAGRRVIATVRDEAGRARVSALGAEVLTVDVA
CCCCCCCCEEEEECCCCCCHHHHHHHHHHCHHEEEHHHHCCCHHHHHHHCCEEEEEECC
RPASVSGLAWQLDGEKIGLALYVAGVIRRPGALTPPTQEDFDAVMHTNVLGAMQALPQVA
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PLVAEARGVFAFLSSSMSLIGGVPNSGSWLYRTSKAALNMAVAAAQHDYPWATLVTLDPG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEEECCC
WVRTDMGGAGGALEVTESVERMRAVLEGVTPNDRGRLLHHDGRRAAQW
EEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]