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The map label for this gene is yieH [H]

Identifier: 120612996

GI number: 120612996

Start: 4845713

End: 4846438

Strand: Reverse

Name: yieH [H]

Synonym: Aave_4360

Alternate gene names: 120612996

Gene position: 4846438-4845713 (Counterclockwise)

Preceding gene: 120612997

Following gene: 120612994

Centisome position: 90.54

GC content: 71.9

Gene sequence:

>726_bases
ATGCCCACCGACGCCCTGTCGCTGTCCCCTTCCACCCGGCCCGGGACGTTTCCTTCGTTCGGCGCCGTGCTGTTCGATTG
CGACGGCGTGCTGGTGGACAGCGAGCCGATCACCCACCGCGTGCTGCGTGCCATGCTGGAGGAGTCCGGATGGCCGCTCA
CGCTCGAGGAGTGCATGCGCATCTTCATCGGCAAGGCCGTGCGCAGCGAAGCCGCCCGGATCGAGGCGGAGACGGGCCGT
CCGTTGACGGACGAGTGGATGGCCCTTTTCTATGAGCGGCGCAATGCCGCGCTGGCTGCGGAGCTGGAGGCCATTGCGGG
CGCGCGGCAGGCCGTGGAGGCGGCGCACGCCCGCACGTCGGGGCGCATCGCTTGCGCATCCGGCGCCGACCGGCACAAGG
TGGAGCTGCAGCTTTCGAAGGTGGGACTGCTGCCGCACTTCCAGGGGCGCGTGTTCAGCGGGCACGAGATGCCCCGCACC
AAGCCGGCGCCGGACGTGTACCTGGCCGCGGCCGCAGCGTTGGGGGTGGCGCCCGCCCGGTGCCTCGTCGTCGAGGACAC
GGTGACGGGCGTCACCGCGGGCGTGGCCGCCGGGGCTGCCGTGGTGGGCTACAGCCCGGCGGCCTGGGGCCACGACGCCG
CCGAAGCCTTGCGGGCGGCAGGGGCCTTCACGGTCATCGGTTCGATGGCCGAGTTGCCGGATTTCCTGGGCAAGGCGCCG
GCTTAA

Upstream 100 bases:

>100_bases
GCGGGCGCCAGGCCCGCATGCGGTAGATTCGATTGTGCTTTGCGGCGCTCCAGGCGGGCGCCGCTTTTTGGCGCGCACTT
TCAACGGATCTATCTCTGCC

Downstream 100 bases:

>100_bases
CGGTTGCTAGAACTTCCACCATTTCTTGTTTTTCTTCGCTGGCCTTTCGTGCGTTCGGGACGTGGCGGGGGGCGGCTCCG
CATTACGGTCTGCGGTGGCG

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MPTDALSLSPSTRPGTFPSFGAVLFDCDGVLVDSEPITHRVLRAMLEESGWPLTLEECMRIFIGKAVRSEAARIEAETGR
PLTDEWMALFYERRNAALAAELEAIAGARQAVEAAHARTSGRIACASGADRHKVELQLSKVGLLPHFQGRVFSGHEMPRT
KPAPDVYLAAAAALGVAPARCLVVEDTVTGVTAGVAAGAAVVGYSPAAWGHDAAEALRAAGAFTVIGSMAELPDFLGKAP
A

Sequences:

>Translated_241_residues
MPTDALSLSPSTRPGTFPSFGAVLFDCDGVLVDSEPITHRVLRAMLEESGWPLTLEECMRIFIGKAVRSEAARIEAETGR
PLTDEWMALFYERRNAALAAELEAIAGARQAVEAAHARTSGRIACASGADRHKVELQLSKVGLLPHFQGRVFSGHEMPRT
KPAPDVYLAAAAALGVAPARCLVVEDTVTGVTAGVAAGAAVVGYSPAAWGHDAAEALRAAGAFTVIGSMAELPDFLGKAP
A
>Mature_240_residues
PTDALSLSPSTRPGTFPSFGAVLFDCDGVLVDSEPITHRVLRAMLEESGWPLTLEECMRIFIGKAVRSEAARIEAETGRP
LTDEWMALFYERRNAALAAELEAIAGARQAVEAAHARTSGRIACASGADRHKVELQLSKVGLLPHFQGRVFSGHEMPRTK
PAPDVYLAAAAALGVAPARCLVVEDTVTGVTAGVAAGAAVVGYSPAAWGHDAAEALRAAGAFTVIGSMAELPDFLGKAPA

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=212, Percent_Identity=31.6037735849057, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789046, Length=188, Percent_Identity=27.1276595744681, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788021, Length=181, Percent_Identity=30.939226519337, Blast_Score=61, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116008157, Length=185, Percent_Identity=33.5135135135135, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25219; Mature: 25088

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDALSLSPSTRPGTFPSFGAVLFDCDGVLVDSEPITHRVLRAMLEESGWPLTLEECMR
CCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHCCCCEEHHHHHH
IFIGKAVRSEAARIEAETGRPLTDEWMALFYERRNAALAAELEAIAGARQAVEAAHARTS
HHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
GRIACASGADRHKVELQLSKVGLLPHFQGRVFSGHEMPRTKPAPDVYLAAAAALGVAPAR
CCEEECCCCCCEEEEEEEEHCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCE
CLVVEDTVTGVTAGVAAGAAVVGYSPAAWGHDAAEALRAAGAFTVIGSMAELPDFLGKAP
EEEEECCHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
A
C
>Mature Secondary Structure 
PTDALSLSPSTRPGTFPSFGAVLFDCDGVLVDSEPITHRVLRAMLEESGWPLTLEECMR
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHCCCCEEHHHHHH
IFIGKAVRSEAARIEAETGRPLTDEWMALFYERRNAALAAELEAIAGARQAVEAAHARTS
HHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
GRIACASGADRHKVELQLSKVGLLPHFQGRVFSGHEMPRTKPAPDVYLAAAAALGVAPAR
CCEEECCCCCCEEEEEEEEHCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCE
CLVVEDTVTGVTAGVAAGAAVVGYSPAAWGHDAAEALRAAGAFTVIGSMAELPDFLGKAP
EEEEECCHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]