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The map label for this gene is baeS [H]

Identifier: 120612956

GI number: 120612956

Start: 4798509

End: 4799588

Strand: Reverse

Name: baeS [H]

Synonym: Aave_4320

Alternate gene names: 120612956

Gene position: 4799588-4798509 (Counterclockwise)

Preceding gene: 120612957

Following gene: 120612955

Centisome position: 89.67

GC content: 70.65

Gene sequence:

>1080_bases
ATGGCCCTGCTCGCCGCGAGCGTGATGCTGTTTTCCGAAGTGCAGTACCGCGACTTCTACCGCAGCCTGCCTTCCGACGT
GCAGGTCGAGCTGGACAGCCTGCGCGACCGCGACATGGAGGACAGCCCGCGGGCGATGGAGATCTACGGCCAGTACTGGC
ACGGCGACCTGCTGTTCGGCGAGAAGTGGTCCCTCGTGGTGGGGCTCGTGGTCTGCCTGCCGGTCGGCCTGGCGGTGGGG
TTCTGGGTGTCGCGCATCGTGACGCAGCCGCTGGCGTCCATGGCCGAGGTGGCGTCCCACGTGGCGATGGGGGATTTTTC
GGTGCGGGCCCAGCCCGGCCGCTACCACGACGAGATGGCGGAAATGGTCCGGCATTTCAACCAGATGATCGATGCGCTCG
AACGCTCGGCCAAGGAGCGGCGCGCCCATGCGGCCTCCATCTCGCACGAGCTGCGCACGCCGCTCACGGTGCTGCGCGCG
CGCCTGCATGCGATCTGCGATGGCGTGATCGAGGCCGACGCACAAGAGTCCCGCGCGCTGCTGGAGCAGGTCGAGTACCT
GGGGCGGCTGGTGGGCGACCTGCACACGCTGTCCATGGCGGAGGCGGACCAGCTCTCGCTGGAAACCCGCGCGGTGGACC
TGGCCGAGTTCGTGAGCGACGCGGTGGCCGTGCATGCCCGGCGCATCGAGGACCATGGCGTGGCGCTGGCGCTGCGGCTG
CCCGAAACGCAGGGTCCCCGTGCCATGGTGGACCCGGACCGCCTGCGCCAGATCCTTTTCAACCTCGTCGAGAACGTGCT
GCGCCACGCGGCGGCGGGTGGCCGGATGGAGATCGAAGTGGCCTCCGAAGGCGATCGCGCTGTGCTGCGCGTGAGCGACG
CGGGCCCCGGCATGCCGGCGCGCCTGCTGGAGCGGCCCTTCGAGCGCTTCCCCCATGAGCCCGGGCGGCGGGGCGAGGGC
TCCGGTCTGGGCCTGTCCATCGTGAAGGCGCTGGCGCAGCGCCAGGGCGGGGGCGTGCGGGTGGAGAACCGCCCCGAAGG
CGGCGCGTGCTTCACGGTGGAGTTCCCCCTCATCGCCTGA

Upstream 100 bases:

>100_bases
ACCGTTGCCTGAGCACCGCGCACCGGCCGTGCAGGGGTCGCTGTTCAGCCGGGTCTGGGTGCGCTTCGGCGTGTGCATCG
CCGCCACCGTGCTGGCGACG

Downstream 100 bases:

>100_bases
AGCCGGCCATGGCACGCAGTCCTACGTGCCCAGCCGCCCATGGACCACAACCGGGCAGGGGCCGGCTGCCTACGATCACA
TCCATGCCGAGCAGCGATGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MALLAASVMLFSEVQYRDFYRSLPSDVQVELDSLRDRDMEDSPRAMEIYGQYWHGDLLFGEKWSLVVGLVVCLPVGLAVG
FWVSRIVTQPLASMAEVASHVAMGDFSVRAQPGRYHDEMAEMVRHFNQMIDALERSAKERRAHAASISHELRTPLTVLRA
RLHAICDGVIEADAQESRALLEQVEYLGRLVGDLHTLSMAEADQLSLETRAVDLAEFVSDAVAVHARRIEDHGVALALRL
PETQGPRAMVDPDRLRQILFNLVENVLRHAAAGGRMEIEVASEGDRAVLRVSDAGPGMPARLLERPFERFPHEPGRRGEG
SGLGLSIVKALAQRQGGGVRVENRPEGGACFTVEFPLIA

Sequences:

>Translated_359_residues
MALLAASVMLFSEVQYRDFYRSLPSDVQVELDSLRDRDMEDSPRAMEIYGQYWHGDLLFGEKWSLVVGLVVCLPVGLAVG
FWVSRIVTQPLASMAEVASHVAMGDFSVRAQPGRYHDEMAEMVRHFNQMIDALERSAKERRAHAASISHELRTPLTVLRA
RLHAICDGVIEADAQESRALLEQVEYLGRLVGDLHTLSMAEADQLSLETRAVDLAEFVSDAVAVHARRIEDHGVALALRL
PETQGPRAMVDPDRLRQILFNLVENVLRHAAAGGRMEIEVASEGDRAVLRVSDAGPGMPARLLERPFERFPHEPGRRGEG
SGLGLSIVKALAQRQGGGVRVENRPEGGACFTVEFPLIA
>Mature_358_residues
ALLAASVMLFSEVQYRDFYRSLPSDVQVELDSLRDRDMEDSPRAMEIYGQYWHGDLLFGEKWSLVVGLVVCLPVGLAVGF
WVSRIVTQPLASMAEVASHVAMGDFSVRAQPGRYHDEMAEMVRHFNQMIDALERSAKERRAHAASISHELRTPLTVLRAR
LHAICDGVIEADAQESRALLEQVEYLGRLVGDLHTLSMAEADQLSLETRAVDLAEFVSDAVAVHARRIEDHGVALALRLP
ETQGPRAMVDPDRLRQILFNLVENVLRHAAAGGRMEIEVASEGDRAVLRVSDAGPGMPARLLERPFERFPHEPGRRGEGS
GLGLSIVKALAQRQGGGVRVENRPEGGACFTVEFPLIA

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=35.7933579335793, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786783, Length=280, Percent_Identity=29.2857142857143, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=28.2608695652174, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=29.5081967213115, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=32.4444444444444, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=29.2418772563177, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=31.6872427983539, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=28.8, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789149, Length=339, Percent_Identity=24.188790560472, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=25.462962962963, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786600, Length=279, Percent_Identity=28.673835125448, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=23.9837398373984, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=289, Percent_Identity=25.9515570934256, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=217, Percent_Identity=25.3456221198157, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=26.9360269360269, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=26.8, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=260, Percent_Identity=23.8461538461538, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789403, Length=233, Percent_Identity=27.0386266094421, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788279, Length=326, Percent_Identity=21.1656441717791, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39646; Mature: 39515

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLAASVMLFSEVQYRDFYRSLPSDVQVELDSLRDRDMEDSPRAMEIYGQYWHGDLLFG
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEC
EKWSLVVGLVVCLPVGLAVGFWVSRIVTQPLASMAEVASHVAMGDFSVRAQPGRYHDEMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHH
EMVRHFNQMIDALERSAKERRAHAASISHELRTPLTVLRARLHAICDGVIEADAQESRAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LEQVEYLGRLVGDLHTLSMAEADQLSLETRAVDLAEFVSDAVAVHARRIEDHGVALALRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
PETQGPRAMVDPDRLRQILFNLVENVLRHAAAGGRMEIEVASEGDRAVLRVSDAGPGMPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCCCH
RLLERPFERFPHEPGRRGEGSGLGLSIVKALAQRQGGGVRVENRPEGGACFTVEFPLIA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
ALLAASVMLFSEVQYRDFYRSLPSDVQVELDSLRDRDMEDSPRAMEIYGQYWHGDLLFG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEC
EKWSLVVGLVVCLPVGLAVGFWVSRIVTQPLASMAEVASHVAMGDFSVRAQPGRYHDEMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHH
EMVRHFNQMIDALERSAKERRAHAASISHELRTPLTVLRARLHAICDGVIEADAQESRAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LEQVEYLGRLVGDLHTLSMAEADQLSLETRAVDLAEFVSDAVAVHARRIEDHGVALALRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
PETQGPRAMVDPDRLRQILFNLVENVLRHAAAGGRMEIEVASEGDRAVLRVSDAGPGMPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCCCH
RLLERPFERFPHEPGRRGEGSGLGLSIVKALAQRQGGGVRVENRPEGGACFTVEFPLIA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]