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The map label for this gene is ltrA [H]

Identifier: 120612951

GI number: 120612951

Start: 4793427

End: 4794413

Strand: Direct

Name: ltrA [H]

Synonym: Aave_4315

Alternate gene names: 120612951

Gene position: 4793427-4794413 (Clockwise)

Preceding gene: 120612937

Following gene: 120612958

Centisome position: 89.55

GC content: 70.21

Gene sequence:

>987_bases
ATGGACCTGCCCTCGCTGACCCTGCTGGTCGAGATCATCGACAGCGGCAACCTGAGCCAGGCCGCGCGCAAGCTGCGCAT
GACCCGCGCGAACGTGAGCTACCACCTCACCAAGCTGGAGAAGGCCGTGGGGGTGCAGCTGGTGCAGCGCACCACGCGCC
GGGTGGAGCCCACCGAGATCGGCCTGCGCCTCTACGAACACGGCCGCACCATCCGCAACGAACTGATGGCCGCGCAGGAA
GCCGTCACCACGCTGGGCCAGGGCCTGCAGGGCCGCGTGGGTATCAGCGTGCCCAGCGGCTACGGGCAGATCGTGATGGG
CGACTGGCTGATCGAGTTCAAGCGCATGTATCCGGGCATCGTGCTGGACGTGCTGTTCGAGAACCGCGCCGACAACCTGC
GCGACGAGGTGGACATCGCCATCCGCGTGGTGCAGGAGCCGCCCCTCTCGCTCGTGGCGCGCAGCCTGGGCAACGTGCGC
TACCTGGCCTGCGCCTCCGCCGACTACGCCCGCCGGCACGGCCTGCCGCGCACGCTGCACGCGCTGCGCGCCGGCCCCGT
CATCACCGCCGGCGTGACCGGCCGCCAGCTGCGCCTTTCGGCCTACCAGGGCGCCGAGCGGCACGAGGTGCTGCTGGAGC
CCACGCTGATCTCCGAGCATTTCCCGTTCCTGCGCCAGGGCATCCTCGCCGGGCTGGGCGTGGGGCTGGTGCCCGACTAC
GTGGTGCAGGACAAGCTCGCCACCGGCGAGGTGCTGACCACGCTGGACGAATACCGCCTGAGCATCTTCGGCACCCACAT
GTACCTGCTGTACCTGCCCAACCGCCACCAGACGCGGGCCGTGCGGACCTGCATCGATTTCCTGCTGGACAAGGCGCAGC
ATGCGGAAGGAGGCGTGCCCGCCGAATCTGCCGAGGAAGGGGACGGGACGGCACCCTCCCCGGCCACCATCGCGGCAGCG
GTGCGGACGCCCCCTGGCCGCTCTTGA

Upstream 100 bases:

>100_bases
ACTTGTCCGGGACATTCTTGCGGCGACAATGTTTTCTGACAATCCCATCATCCATTGACAGACTGTCAAAGGATTTAAAC
CAATCGATCGGAATGCTTCC

Downstream 100 bases:

>100_bases
AAAAGCGCCGCAAAGAAAAACCCCCGCCATGTCGCCACGGCGGAGGTTTCGTCTTGCTTCTTTCCTGCCGGCAGCCGTAA
CCGGGCTGCCATGCGGAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDLPSLTLLVEIIDSGNLSQAARKLRMTRANVSYHLTKLEKAVGVQLVQRTTRRVEPTEIGLRLYEHGRTIRNELMAAQE
AVTTLGQGLQGRVGISVPSGYGQIVMGDWLIEFKRMYPGIVLDVLFENRADNLRDEVDIAIRVVQEPPLSLVARSLGNVR
YLACASADYARRHGLPRTLHALRAGPVITAGVTGRQLRLSAYQGAERHEVLLEPTLISEHFPFLRQGILAGLGVGLVPDY
VVQDKLATGEVLTTLDEYRLSIFGTHMYLLYLPNRHQTRAVRTCIDFLLDKAQHAEGGVPAESAEEGDGTAPSPATIAAA
VRTPPGRS

Sequences:

>Translated_328_residues
MDLPSLTLLVEIIDSGNLSQAARKLRMTRANVSYHLTKLEKAVGVQLVQRTTRRVEPTEIGLRLYEHGRTIRNELMAAQE
AVTTLGQGLQGRVGISVPSGYGQIVMGDWLIEFKRMYPGIVLDVLFENRADNLRDEVDIAIRVVQEPPLSLVARSLGNVR
YLACASADYARRHGLPRTLHALRAGPVITAGVTGRQLRLSAYQGAERHEVLLEPTLISEHFPFLRQGILAGLGVGLVPDY
VVQDKLATGEVLTTLDEYRLSIFGTHMYLLYLPNRHQTRAVRTCIDFLLDKAQHAEGGVPAESAEEGDGTAPSPATIAAA
VRTPPGRS
>Mature_328_residues
MDLPSLTLLVEIIDSGNLSQAARKLRMTRANVSYHLTKLEKAVGVQLVQRTTRRVEPTEIGLRLYEHGRTIRNELMAAQE
AVTTLGQGLQGRVGISVPSGYGQIVMGDWLIEFKRMYPGIVLDVLFENRADNLRDEVDIAIRVVQEPPLSLVARSLGNVR
YLACASADYARRHGLPRTLHALRAGPVITAGVTGRQLRLSAYQGAERHEVLLEPTLISEHFPFLRQGILAGLGVGLVPDY
VVQDKLATGEVLTTLDEYRLSIFGTHMYLLYLPNRHQTRAVRTCIDFLLDKAQHAEGGVPAESAEEGDGTAPSPATIAAA
VRTPPGRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=27.5510204081633, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786401, Length=303, Percent_Identity=28.7128712871287, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=26.9896193771626, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=27.2413793103448, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=24.4827586206897, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=21.5753424657534, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=138, Percent_Identity=34.7826086956522, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35972; Mature: 35972

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPSLTLLVEIIDSGNLSQAARKLRMTRANVSYHLTKLEKAVGVQLVQRTTRRVEPTEI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GLRLYEHGRTIRNELMAAQEAVTTLGQGLQGRVGISVPSGYGQIVMGDWLIEFKRMYPGI
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHCCCC
VLDVLFENRADNLRDEVDIAIRVVQEPPLSLVARSLGNVRYLACASADYARRHGLPRTLH
EEHHHHHCCCCCHHHHHEEEEEEECCCCHHHHHHHHCCEEEEEECCCHHHHHCCCHHHHH
ALRAGPVITAGVTGRQLRLSAYQGAERHEVLLEPTLISEHFPFLRQGILAGLGVGLVPDY
HHHCCCEEEECCCCCEEEEHHHCCCCCCCEEECCHHHHHCCHHHHHHHHHHCCCCCCCHH
VVQDKLATGEVLTTLDEYRLSIFGTHMYLLYLPNRHQTRAVRTCIDFLLDKAQHAEGGVP
HHHCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AESAEEGDGTAPSPATIAAAVRTPPGRS
CCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDLPSLTLLVEIIDSGNLSQAARKLRMTRANVSYHLTKLEKAVGVQLVQRTTRRVEPTEI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GLRLYEHGRTIRNELMAAQEAVTTLGQGLQGRVGISVPSGYGQIVMGDWLIEFKRMYPGI
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHCCCC
VLDVLFENRADNLRDEVDIAIRVVQEPPLSLVARSLGNVRYLACASADYARRHGLPRTLH
EEHHHHHCCCCCHHHHHEEEEEEECCCCHHHHHHHHCCEEEEEECCCHHHHHCCCHHHHH
ALRAGPVITAGVTGRQLRLSAYQGAERHEVLLEPTLISEHFPFLRQGILAGLGVGLVPDY
HHHCCCEEEECCCCCEEEEHHHCCCCCCCEEECCHHHHHCCHHHHHHHHHHCCCCCCCHH
VVQDKLATGEVLTTLDEYRLSIFGTHMYLLYLPNRHQTRAVRTCIDFLLDKAQHAEGGVP
HHHCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AESAEEGDGTAPSPATIAAAVRTPPGRS
CCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]