Click here to switch to the map view.

The map label for this gene is arpC [H]

Identifier: 120612958

GI number: 120612958

Start: 4800508

End: 4802055

Strand: Direct

Name: arpC [H]

Synonym: Aave_4322

Alternate gene names: 120612958

Gene position: 4800508-4802055 (Clockwise)

Preceding gene: 120612951

Following gene: 120612959

Centisome position: 89.68

GC content: 75.71

Gene sequence:

>1548_bases
ATGCCATGCAAGGCGGCTCAAGCTTGGGGCGGTCCAATCCAGCCATCGCCATGGGCTTCTCCGCCCTGGCTCCACCCTGC
AAATGTAACGCCGCGCGTGCTTCTTCCGTCCCCCATTCCACGTCCGCTCCGCCTCGGCCTGGCTGCCGCGGCGATCGCGT
TCCTGGCCGGCTGCTCGGCGCCGGACATCCGCCGCCCGGAAGCGCCCGCCCTGCCCGCCACCTGGACCTCGCCCGTACCG
GAGGGCGCCGCCGCGGCGCCGGAGTTCCGCGCCTGGTGGAAGGCTTTCCACGATCCGGCCCTCGACGCGCTGGTGGATGA
GGCGCTGCAGAAGAATCTCGATCTGGCGATCGCCGCCCACCGCCTGCGCGAAGCCCGCCTGCAGGCCGGGCGCGCGGCGG
TGCAGTTCCGACCGTCGTTCGGCGCCGGTGCGCGCACGCTGCAGGACATCGAAGCCGCCGACAGCTATTTCCACGCCAGC
ATCGACATGGTGTGGGAACTGGGCCTGTTCGGCGCCGCCGGGAGCGCGCGGGCGTCGGCCGCGGCGGACCGCGACGCGGC
CGTGGCGGACCGCCAGGGTGCGCGCGTCGCCGTCGTGGCCGAGGTGGTGCGCAATTACCTGGACCTGCAGGCCGCGCGCC
GGCAGTTGCAGTTGCTCGACCGGCAGGCCGCCCTCGACGAGCGGGCCGCCCGGCTGGCGGAGGTGCGCCGCCGCACCTGG
ACCGGCGCCACCGACGAGGTGGCCTCGGCCGGGGTGCAGCGCGCCCGCACCCGAGCTGCACGGGCCGAGCCCGAACAGGC
GCGCGCCCGCGCGGCACAGTCGCTGGCCGTGCTGCTGGACCGCGTGGCGCCGGACCCGGCCTGGTACGCCGACGGCCCCG
CCCGGGTGCCCGCCCTGGCGCCCTTCGCATTCCCGGCGCTGCCCGCCGACCTGCTGCGCACGCGCCCCGATGTGCAGGCC
GCGGAAGCGGCCGTTCGCAAGGCCGCGGCCGAGGTGGGCGTGGCCCGCTCCGAGCTGTACCCGCGCATCGCCATCACCGG
CTCGCTGCTGTACGCCTACAACCTCACGCGCAACCGCCGCACCACCAGCGACAACGTGCCCGCCATCGGGCCCACCATCG
ACATCCCGCTCCTGGACTGGGGACGCCGGCGCATGCAGGTGGACGCGCAGCAGGAGGCACTACAGGCCGCCGAGCTGTCC
TACCAGCGCACGGTGCGCAGCGCCGTCGCCGAAGCCGAAGGCGCCCTCTCCGCCCTGGCGGCCCAGCAGAACCGGGCGGA
CGCCCTCGCGCAGGCGCGACCCGCGCTCGCCGAGCGCGTGCGGGCGGCCGACGTCCAGGCGCGGCTGGGCCTGGCCAGCG
AATACGACGGGCTCGCCGCGCAGCGCGCGGCCCTGCAGGCCGAAGCCGAATGGGCCACGGCGCAGGACGCGCGCTCGCTG
GCGTTCGTCGCGCTGTACAAGGCGCTGGGCGGCGCTCCCCTGCCCGCGGAACCGCCAGACGCGGTCACGGATGCCCCTCC
CGAGGCGCCCTCCGGAGAGGCGCCGTGA

Upstream 100 bases:

>100_bases
CAGCGGGAAGGTTCATGGCGTCGGGAAGTGCTGGGGCGGAATTATCCACAGCGGCCGCCGACCTGCAGGACAAAGCCCGG
CGTCTCCATGAAGCCTCCAT

Downstream 100 bases:

>100_bases
TCGCCCTGGCCCGCAAGACGCTGGTCCACGAGTGGCGGCGGTTCGTACCCGCGGTGTTCGCCGTGGGCTTCTCGTGCGTG
CTGCTGGTGGTGCAGGCCGC

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MPCKAAQAWGGPIQPSPWASPPWLHPANVTPRVLLPSPIPRPLRLGLAAAAIAFLAGCSAPDIRRPEAPALPATWTSPVP
EGAAAAPEFRAWWKAFHDPALDALVDEALQKNLDLAIAAHRLREARLQAGRAAVQFRPSFGAGARTLQDIEAADSYFHAS
IDMVWELGLFGAAGSARASAAADRDAAVADRQGARVAVVAEVVRNYLDLQAARRQLQLLDRQAALDERAARLAEVRRRTW
TGATDEVASAGVQRARTRAARAEPEQARARAAQSLAVLLDRVAPDPAWYADGPARVPALAPFAFPALPADLLRTRPDVQA
AEAAVRKAAAEVGVARSELYPRIAITGSLLYAYNLTRNRRTTSDNVPAIGPTIDIPLLDWGRRRMQVDAQQEALQAAELS
YQRTVRSAVAEAEGALSALAAQQNRADALAQARPALAERVRAADVQARLGLASEYDGLAAQRAALQAEAEWATAQDARSL
AFVALYKALGGAPLPAEPPDAVTDAPPEAPSGEAP

Sequences:

>Translated_515_residues
MPCKAAQAWGGPIQPSPWASPPWLHPANVTPRVLLPSPIPRPLRLGLAAAAIAFLAGCSAPDIRRPEAPALPATWTSPVP
EGAAAAPEFRAWWKAFHDPALDALVDEALQKNLDLAIAAHRLREARLQAGRAAVQFRPSFGAGARTLQDIEAADSYFHAS
IDMVWELGLFGAAGSARASAAADRDAAVADRQGARVAVVAEVVRNYLDLQAARRQLQLLDRQAALDERAARLAEVRRRTW
TGATDEVASAGVQRARTRAARAEPEQARARAAQSLAVLLDRVAPDPAWYADGPARVPALAPFAFPALPADLLRTRPDVQA
AEAAVRKAAAEVGVARSELYPRIAITGSLLYAYNLTRNRRTTSDNVPAIGPTIDIPLLDWGRRRMQVDAQQEALQAAELS
YQRTVRSAVAEAEGALSALAAQQNRADALAQARPALAERVRAADVQARLGLASEYDGLAAQRAALQAEAEWATAQDARSL
AFVALYKALGGAPLPAEPPDAVTDAPPEAPSGEAP
>Mature_514_residues
PCKAAQAWGGPIQPSPWASPPWLHPANVTPRVLLPSPIPRPLRLGLAAAAIAFLAGCSAPDIRRPEAPALPATWTSPVPE
GAAAAPEFRAWWKAFHDPALDALVDEALQKNLDLAIAAHRLREARLQAGRAAVQFRPSFGAGARTLQDIEAADSYFHASI
DMVWELGLFGAAGSARASAAADRDAAVADRQGARVAVVAEVVRNYLDLQAARRQLQLLDRQAALDERAARLAEVRRRTWT
GATDEVASAGVQRARTRAARAEPEQARARAAQSLAVLLDRVAPDPAWYADGPARVPALAPFAFPALPADLLRTRPDVQAA
EAAVRKAAAEVGVARSELYPRIAITGSLLYAYNLTRNRRTTSDNVPAIGPTIDIPLLDWGRRRMQVDAQQEALQAAELSY
QRTVRSAVAEAEGALSALAAQQNRADALAQARPALAERVRAADVQARLGLASEYDGLAAQRAALQAEAEWATAQDARSLA
FVALYKALGGAPLPAEPPDAVTDAPPEAPSGEAP

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=454, Percent_Identity=25.5506607929515, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI2367348, Length=438, Percent_Identity=24.8858447488584, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54664; Mature: 54533

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCKAAQAWGGPIQPSPWASPPWLHPANVTPRVLLPSPIPRPLRLGLAAAAIAFLAGCSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCC
PDIRRPEAPALPATWTSPVPEGAAAAPEFRAWWKAFHDPALDALVDEALQKNLDLAIAAH
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHH
RLREARLQAGRAAVQFRPSFGAGARTLQDIEAADSYFHASIDMVWELGLFGAAGSARASA
HHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AADRDAAVADRQGARVAVVAEVVRNYLDLQAARRQLQLLDRQAALDERAARLAEVRRRTW
HCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGATDEVASAGVQRARTRAARAEPEQARARAAQSLAVLLDRVAPDPAWYADGPARVPALA
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PFAFPALPADLLRTRPDVQAAEAAVRKAAAEVGVARSELYPRIAITGSLLYAYNLTRNRR
CHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCC
TTSDNVPAIGPTIDIPLLDWGRRRMQVDAQQEALQAAELSYQRTVRSAVAEAEGALSALA
CCCCCCCCCCCCCCCCCHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQNRADALAQARPALAERVRAADVQARLGLASEYDGLAAQRAALQAEAEWATAQDARSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHH
AFVALYKALGGAPLPAEPPDAVTDAPPEAPSGEAP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PCKAAQAWGGPIQPSPWASPPWLHPANVTPRVLLPSPIPRPLRLGLAAAAIAFLAGCSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCC
PDIRRPEAPALPATWTSPVPEGAAAAPEFRAWWKAFHDPALDALVDEALQKNLDLAIAAH
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHH
RLREARLQAGRAAVQFRPSFGAGARTLQDIEAADSYFHASIDMVWELGLFGAAGSARASA
HHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AADRDAAVADRQGARVAVVAEVVRNYLDLQAARRQLQLLDRQAALDERAARLAEVRRRTW
HCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGATDEVASAGVQRARTRAARAEPEQARARAAQSLAVLLDRVAPDPAWYADGPARVPALA
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PFAFPALPADLLRTRPDVQAAEAAVRKAAAEVGVARSELYPRIAITGSLLYAYNLTRNRR
CHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCC
TTSDNVPAIGPTIDIPLLDWGRRRMQVDAQQEALQAAELSYQRTVRSAVAEAEGALSALA
CCCCCCCCCCCCCCCCCHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQNRADALAQARPALAERVRAADVQARLGLASEYDGLAAQRAALQAEAEWATAQDARSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHH
AFVALYKALGGAPLPAEPPDAVTDAPPEAPSGEAP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]