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The map label for this gene is etfA [H]

Identifier: 120612942

GI number: 120612942

Start: 4782316

End: 4783248

Strand: Reverse

Name: etfA [H]

Synonym: Aave_4306

Alternate gene names: 120612942

Gene position: 4783248-4782316 (Counterclockwise)

Preceding gene: 120612943

Following gene: 120612941

Centisome position: 89.36

GC content: 69.99

Gene sequence:

>933_bases
ATGACCTCTCTCGTTATTGCAGAACACGACAACGCTTCGATCAAGCCCGCCACGCTCCACACCGTCACGGCGGCTGCCGC
CTGCGGCGGTGACGTGCACGTGCTGGTGGCAGGCCAGGGCGCGGATGCCGCCGCCCAGGCCGCCGCGCAGATCGCGGGCG
TTACCAAGGTCATCCTGGCCGACGGCGCAAGCCTCAAGGACGGCCTGGCCGAGAACGTGGCCGCCCAGGTGCTGGCCATC
GCTTCCAACTACAGCCACATCCTGTTCCCGGCCACGGCCGGCGGCAAGAACGTGGCGCCGCGGGTGGCGGCGAAGCTCGA
TGTCGCGCAGATCAGCGACATCACCAGGGTGGACGGCCCGGACACGTTCGAGCGCCCGATCTACGCGGGCAACGCGATCG
CCACGGTGCAAAGCAGCGACAGCGTGAAGGTGATCACCGTGCGCACCACGGGCTTCGACGCCGCGGCGGCGACGGGCGGC
TCGGCGGCGGTGGAGAAGGCCGATGCGGCCGCGGACAGCGGCAAGAGCCAGTTCGTGGGCCGCGAGGTCACCAAGAGCGA
CCGGCCCGAGCTCACGGCGGCCAAGATCATCGTCTCGGGCGGCCGGGCGCTGGGCAGCGCGGAGAAGTTCAACGAGGTGA
TGACGCCGCTGGCGGACAAGCTGGGCGCGGCGATCGGCGCGAGCCGCGCGGCGGTGGATGCGGGCTATGCACCGAACGAC
CTGCAGGTGGGGCAGACGGGCAAGATCGTGGCGCCGCAGCTCTACATCGCGGCGGGCATCTCGGGCGCGATCCAGCATCT
GGCGGGCATGAAGGATTCCAAGGTGATCGTGGCGATCAACAAGGACGCCGAGGCGCCGATCTTCAGCGTGGCCGACTACG
GGCTGGAGGCGGACCTGTTCACCGCCGTGCCGGAGCTGGTCGGCCGGCTCTGA

Upstream 100 bases:

>100_bases
CGGGGCGGCCCTTCCTCGGTGTCCCTCGCATCGGCCGCGCCGGAACTGAAAGCCGCGGGCGATACAGGTATCCCTGACAT
TCAAGAGAAAGACGACTGAA

Downstream 100 bases:

>100_bases
GGCGTGTGCCGTGCGCCCGTATTGAACGGAAGAAAGGTTTCACCATGAATGCAATCCCCGAGGCTTCCAGCGTGCGCAGC
CAGGTCACGCCCGAGGAATG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTSLVIAEHDNASIKPATLHTVTAAAACGGDVHVLVAGQGADAAAQAAAQIAGVTKVILADGASLKDGLAENVAAQVLAI
ASNYSHILFPATAGGKNVAPRVAAKLDVAQISDITRVDGPDTFERPIYAGNAIATVQSSDSVKVITVRTTGFDAAAATGG
SAAVEKADAAADSGKSQFVGREVTKSDRPELTAAKIIVSGGRALGSAEKFNEVMTPLADKLGAAIGASRAAVDAGYAPND
LQVGQTGKIVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLEADLFTAVPELVGRL

Sequences:

>Translated_310_residues
MTSLVIAEHDNASIKPATLHTVTAAAACGGDVHVLVAGQGADAAAQAAAQIAGVTKVILADGASLKDGLAENVAAQVLAI
ASNYSHILFPATAGGKNVAPRVAAKLDVAQISDITRVDGPDTFERPIYAGNAIATVQSSDSVKVITVRTTGFDAAAATGG
SAAVEKADAAADSGKSQFVGREVTKSDRPELTAAKIIVSGGRALGSAEKFNEVMTPLADKLGAAIGASRAAVDAGYAPND
LQVGQTGKIVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLEADLFTAVPELVGRL
>Mature_309_residues
TSLVIAEHDNASIKPATLHTVTAAAACGGDVHVLVAGQGADAAAQAAAQIAGVTKVILADGASLKDGLAENVAAQVLAIA
SNYSHILFPATAGGKNVAPRVAAKLDVAQISDITRVDGPDTFERPIYAGNAIATVQSSDSVKVITVRTTGFDAAAATGGS
AAVEKADAAADSGKSQFVGREVTKSDRPELTAAKIIVSGGRALGSAEKFNEVMTPLADKLGAAIGASRAAVDAGYAPNDL
QVGQTGKIVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLEADLFTAVPELVGRL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=307, Percent_Identity=59.6091205211726, Blast_Score=350, Evalue=9e-97,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=60.1476014760148, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1786226, Length=236, Percent_Identity=34.3220338983051, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787990, Length=294, Percent_Identity=30.952380952381, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082157, Length=243, Percent_Identity=32.0987654320988, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=55.7692307692308, Blast_Score=324, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6325261, Length=283, Percent_Identity=45.2296819787986, Blast_Score=245, Evalue=6e-66,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=61.8589743589744, Blast_Score=358, Evalue=3e-99,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=61.8589743589744, Blast_Score=358, Evalue=3e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31093; Mature: 30962

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLVIAEHDNASIKPATLHTVTAAAACGGDVHVLVAGQGADAAAQAAAQIAGVTKVILA
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHEEEEEE
DGASLKDGLAENVAAQVLAIASNYSHILFPATAGGKNVAPRVAAKLDVAQISDITRVDGP
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHHCCCCC
DTFERPIYAGNAIATVQSSDSVKVITVRTTGFDAAAATGGSAAVEKADAAADSGKSQFVG
CCCCCCEECCCEEEEEECCCCEEEEEEEECCCCHHHCCCCCHHHHHHHHHHCCCCHHHCC
REVTKSDRPELTAAKIIVSGGRALGSAEKFNEVMTPLADKLGAAIGASRAAVDAGYAPND
CHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
LQVGQTGKIVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLEADLF
CEECCCCCEECCCEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHHCCCCHHHH
TAVPELVGRL
HHHHHHHCCC
>Mature Secondary Structure 
TSLVIAEHDNASIKPATLHTVTAAAACGGDVHVLVAGQGADAAAQAAAQIAGVTKVILA
CEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHEEEEEE
DGASLKDGLAENVAAQVLAIASNYSHILFPATAGGKNVAPRVAAKLDVAQISDITRVDGP
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHHCCCCC
DTFERPIYAGNAIATVQSSDSVKVITVRTTGFDAAAATGGSAAVEKADAAADSGKSQFVG
CCCCCCEECCCEEEEEECCCCEEEEEEEECCCCHHHCCCCCHHHHHHHHHHCCCCHHHCC
REVTKSDRPELTAAKIIVSGGRALGSAEKFNEVMTPLADKLGAAIGASRAAVDAGYAPND
CHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
LQVGQTGKIVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLEADLF
CEECCCCCEECCCEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHHCCCCHHHH
TAVPELVGRL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]