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The map label for this gene is hpcG [H]

Identifier: 120612905

GI number: 120612905

Start: 4731660

End: 4732508

Strand: Direct

Name: hpcG [H]

Synonym: Aave_4269

Alternate gene names: 120612905

Gene position: 4731660-4732508 (Clockwise)

Preceding gene: 120612904

Following gene: 120612906

Centisome position: 88.4

GC content: 71.26

Gene sequence:

>849_bases
ATGAGCGCCGCGTCCGCTGCATCCTCTCCTCCCGCACCCGCCCTGTCGGCAGACCAGCTCGGCGAAGCGGCGCGGCAACT
CGACGAGGCCGAACGCACGCGCGTGCCCTGCGCCCAGTTCTCGCGACAGTATCCGGACATGGGCATCGATGATGCCTACG
CGATCCAGGACGCGTGGATGCAGCGCAAGCAGGCCCGGGGCCGGCGCGTCATCGGCCACAAGATCGGGCTCACGTCCAAG
GCGATGCAGCGCGCCGTGAACATCGCGGAGCCGGACTTCGGCACGCTGCTGGACGACATGCTCTACCGCGACGGCGCGAG
CCTGCCGGCCGACCGCTTCCTGCAGCTGCGCATCGAGGCCGAGCTCGCCTTCGTGCTCGCGCGGCCCTTGGCAGGCCCGC
ACTGCACGCTCTACGACGTGCTCGACGCCACGGCCTACGTCACCCCGGCGCTGGAGATCCTGGACGCGCGCATCCAGCGC
GTGGACCCGGAGACCGGCCGCACGCGCACCGTCATCGACACCATCTCCGACAACGCGGCCAACGCCGCACTGGTGCTCGG
CGGCCGGCCTTTCAGGCCCGCGCTGCTCGACGCGGATCTGCGGCGCATCGGCGCCATCGTCACGCGCAACGGCGACGTGG
AAGAGACCGGGCTCGCGGCCGGCGTGCTGAACCATCCCGCCAACGGCGTGGCCTGGCTCGCCAACCGGCTGCACCGCCAC
GGCATCGCGCTGCAGGCCGGCGAAGTGGTGCTCGCGGGGTCGTTCATCCGGCCCATCGACGTGGCCCGTGGCGATACCAT
CGTGGCGGACTACGGCGAGTTCGGCACCGTTGCGTGCCACTTCGGCTGA

Upstream 100 bases:

>100_bases
GCATCCGCTTCGATCCGCCGCGGTTCCTGCAACCCGGCGACGTGGTCGAGGTGGAAGTGGACGGCGTGGGCGTGCTGCGC
AATGCCGTGGAGGCCGAGGC

Downstream 100 bases:

>100_bases
GCGATTCCCCAGACCCCGCTCTCCGCGAAACCGCTTCCTTCCATGCCCCAGCCCAACCGCTTCAAGCGCGCGCTCGCCGC
CGGCCAGCCGCAGATCGGAC

Product: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSAASAASSPPAPALSADQLGEAARQLDEAERTRVPCAQFSRQYPDMGIDDAYAIQDAWMQRKQARGRRVIGHKIGLTSK
AMQRAVNIAEPDFGTLLDDMLYRDGASLPADRFLQLRIEAELAFVLARPLAGPHCTLYDVLDATAYVTPALEILDARIQR
VDPETGRTRTVIDTISDNAANAALVLGGRPFRPALLDADLRRIGAIVTRNGDVEETGLAAGVLNHPANGVAWLANRLHRH
GIALQAGEVVLAGSFIRPIDVARGDTIVADYGEFGTVACHFG

Sequences:

>Translated_282_residues
MSAASAASSPPAPALSADQLGEAARQLDEAERTRVPCAQFSRQYPDMGIDDAYAIQDAWMQRKQARGRRVIGHKIGLTSK
AMQRAVNIAEPDFGTLLDDMLYRDGASLPADRFLQLRIEAELAFVLARPLAGPHCTLYDVLDATAYVTPALEILDARIQR
VDPETGRTRTVIDTISDNAANAALVLGGRPFRPALLDADLRRIGAIVTRNGDVEETGLAAGVLNHPANGVAWLANRLHRH
GIALQAGEVVLAGSFIRPIDVARGDTIVADYGEFGTVACHFG
>Mature_281_residues
SAASAASSPPAPALSADQLGEAARQLDEAERTRVPCAQFSRQYPDMGIDDAYAIQDAWMQRKQARGRRVIGHKIGLTSKA
MQRAVNIAEPDFGTLLDDMLYRDGASLPADRFLQLRIEAELAFVLARPLAGPHCTLYDVLDATAYVTPALEILDARIQRV
DPETGRTRTVIDTISDNAANAALVLGGRPFRPALLDADLRRIGAIVTRNGDVEETGLAAGVLNHPANGVAWLANRLHRHG
IALQAGEVVLAGSFIRPIDVARGDTIVADYGEFGTVACHFG

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=238, Percent_Identity=38.2352941176471, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 30274; Mature: 30142

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASAASSPPAPALSADQLGEAARQLDEAERTRVPCAQFSRQYPDMGIDDAYAIQDAWM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHH
QRKQARGRRVIGHKIGLTSKAMQRAVNIAEPDFGTLLDDMLYRDGASLPADRFLQLRIEA
HHHHHCCCEEHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEEEHH
ELAFVLARPLAGPHCTLYDVLDATAYVTPALEILDARIQRVDPETGRTRTVIDTISDNAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
NAALVLGGRPFRPALLDADLRRIGAIVTRNGDVEETGLAAGVLNHPANGVAWLANRLHRH
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
GIALQAGEVVLAGSFIRPIDVARGDTIVADYGEFGTVACHFG
CCEEECCCEEEECCCCCCCCCCCCCEEEEECCCCCCEEEECC
>Mature Secondary Structure 
SAASAASSPPAPALSADQLGEAARQLDEAERTRVPCAQFSRQYPDMGIDDAYAIQDAWM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHH
QRKQARGRRVIGHKIGLTSKAMQRAVNIAEPDFGTLLDDMLYRDGASLPADRFLQLRIEA
HHHHHCCCEEHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEEEHH
ELAFVLARPLAGPHCTLYDVLDATAYVTPALEILDARIQRVDPETGRTRTVIDTISDNAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
NAALVLGGRPFRPALLDADLRRIGAIVTRNGDVEETGLAAGVLNHPANGVAWLANRLHRH
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
GIALQAGEVVLAGSFIRPIDVARGDTIVADYGEFGTVACHFG
CCEEECCCEEEECCCCCCCCCCCCCEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]