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The map label for this gene is prpL [H]

Identifier: 120612875

GI number: 120612875

Start: 4696918

End: 4698522

Strand: Reverse

Name: prpL [H]

Synonym: Aave_4239

Alternate gene names: 120612875

Gene position: 4698522-4696918 (Counterclockwise)

Preceding gene: 120612876

Following gene: 120612874

Centisome position: 87.78

GC content: 71.09

Gene sequence:

>1605_bases
ATGAACCAAAACATGAAAAATCACAGGGTTTCCAAATGGAAGATCGCGCGCCGGGGCGGCACGCTGGCCGGCATCGCGGC
GGCATTGCTCATCGCAGGATGCGGTGGCGGGGGCGGTTCCACCGCCACGGCCTCCTCGTCCGGCGAAACCGTGCTGCGGG
TGGAGTCTGCGGTGCAACCCGCGGACGCGGCCGTGCCGTCGCGCGCGGCGGCACGCTCCGAGGCCGGGCCGCAGCCCGTG
CGGCTGGCACTGGCGGCATTGCAGTCCACCCGGGCGGAGGAAACGGGGAGGCACGGCGGCCCGCGCAAGGTGGGCACCCT
GCGCACCGTGCCCGAGACGGCCTCGGCCGCCGGACTGGCCGGCCGCCTGCAATGGAAGCCGGCGTCGGACGGCGGCCTGC
GGGCCGCCATCAGCTTCACGGCCGAGGACGCCTACGGCGTGCGCCTGGGCGTGCTGGTGCGCCGGCTGCCCGAATCGGCG
CTGCTGCGCGTGTACCGGCAGGACCGGCCGGACGCCGCCTACGAGACGCGGGGCAGCGACGTCCTGCAGATCCTGGCCCG
CAACGCGGCCGCCGGCGACACGTCGGACGCGGCGAAAACCTGGTGGACGCCCGATACCGGCGGCAGCGAGGCGACGCTGG
AGATCGACCTGCCGGCCGGCACCTCCGCCGATGCGCTCGACATCGCCATCCCGTCGCTGGTGCACATCCAGGAAGACCTC
TCGCTGTCCTCCAGCGGCGATGATGCGCTGGTGACCAAGAACGTCGGCGACGCCGTGGCCTGCAATCTCGACTCCACCTG
CTATGACGACTATGCGCAGCAGCGCAATGCCGTGGCGCGCATGGTCTTCGTGGACTCCACCGGGGCGCATTTCTGCACGG
GCACGCTGCTCAACGACCGCGACGGCACGCGCACGCCGTACTTCCTCACCGCCAACCACTGCATTCCGTCGCAGACGGTG
GCGTCCACGCTGCAGACCGACTGGTTCTTCCGGTCCTCGTCCTGCAACAACCGCACGCTGTCGCCGAACGCGGCGACGCG
CACGGGCGGTGCCGTGCTGCTCTACTCGGGCCCCGATACGGACACGGCCTTCCTGCGCCTCAACGACGCGCCGCCGCCCG
GCGCCGTGTTCGCCGCCTGGGATGCGGGCCTGCAGGCCATGTCCGCCGCGGTCGTCGGCATCCATCATCCACGTGGCGAC
CTGCAGAGGATCAGTTTCGGCAGCATCATGGGCACGCTCGCCTGCTCCGGCGACCTCGAGAGCCTGACCTGCGACTCCGC
GACGGGTGACGCAGCGAACTACTACGATGTCAGCCTCGACCGTGGCACGGTGGAGCACGGCAGCAGCGGCTCGGCACTGT
TCCAGGGGGGCCGGGTGATCGGTACGCTCTACGGGTATTCGGGTGCAGGGCAGTGTTCCCCGGACGGAGTGCGGTTGTAC
GCCCGCTTCGACCACGCCTACCAGGCCGCGCTCAAGCAGTGGCTGTCCCCTGCGACCCCTGCTCGCCACCGTGGCCACCA
GCCGCGCGTGCTTCCCCACCACGGCCACAGCGGCCATGGCACGCCGGCCGCTCCGCAGGAAGCCGCTTCCGTGGCGCAGG
GGTGA

Upstream 100 bases:

>100_bases
GGGGGTCAGCGAGGGCATCAAATTGGCGCTCAAGGCACTGGCGAAGTGAAGTCAGCCCTTCCCGGCACGCCAGTGCCGGA
CGCTGTGGGATGGGCGAAAA

Downstream 100 bases:

>100_bases
TCCGGGCCCGGCGCTTCCCGCGCCGGGCATGCGGGCTTGGACGGCAGCGCCCGCCGGGGCGCTGCCGGTGCCCCGCGTGT
GCCGCCCGCAACGGAACGGG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: Protease IV; pvdS-regulated endoprotease [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MNQNMKNHRVSKWKIARRGGTLAGIAAALLIAGCGGGGGSTATASSSGETVLRVESAVQPADAAVPSRAAARSEAGPQPV
RLALAALQSTRAEETGRHGGPRKVGTLRTVPETASAAGLAGRLQWKPASDGGLRAAISFTAEDAYGVRLGVLVRRLPESA
LLRVYRQDRPDAAYETRGSDVLQILARNAAAGDTSDAAKTWWTPDTGGSEATLEIDLPAGTSADALDIAIPSLVHIQEDL
SLSSSGDDALVTKNVGDAVACNLDSTCYDDYAQQRNAVARMVFVDSTGAHFCTGTLLNDRDGTRTPYFLTANHCIPSQTV
ASTLQTDWFFRSSSCNNRTLSPNAATRTGGAVLLYSGPDTDTAFLRLNDAPPPGAVFAAWDAGLQAMSAAVVGIHHPRGD
LQRISFGSIMGTLACSGDLESLTCDSATGDAANYYDVSLDRGTVEHGSSGSALFQGGRVIGTLYGYSGAGQCSPDGVRLY
ARFDHAYQAALKQWLSPATPARHRGHQPRVLPHHGHSGHGTPAAPQEAASVAQG

Sequences:

>Translated_534_residues
MNQNMKNHRVSKWKIARRGGTLAGIAAALLIAGCGGGGGSTATASSSGETVLRVESAVQPADAAVPSRAAARSEAGPQPV
RLALAALQSTRAEETGRHGGPRKVGTLRTVPETASAAGLAGRLQWKPASDGGLRAAISFTAEDAYGVRLGVLVRRLPESA
LLRVYRQDRPDAAYETRGSDVLQILARNAAAGDTSDAAKTWWTPDTGGSEATLEIDLPAGTSADALDIAIPSLVHIQEDL
SLSSSGDDALVTKNVGDAVACNLDSTCYDDYAQQRNAVARMVFVDSTGAHFCTGTLLNDRDGTRTPYFLTANHCIPSQTV
ASTLQTDWFFRSSSCNNRTLSPNAATRTGGAVLLYSGPDTDTAFLRLNDAPPPGAVFAAWDAGLQAMSAAVVGIHHPRGD
LQRISFGSIMGTLACSGDLESLTCDSATGDAANYYDVSLDRGTVEHGSSGSALFQGGRVIGTLYGYSGAGQCSPDGVRLY
ARFDHAYQAALKQWLSPATPARHRGHQPRVLPHHGHSGHGTPAAPQEAASVAQG
>Mature_534_residues
MNQNMKNHRVSKWKIARRGGTLAGIAAALLIAGCGGGGGSTATASSSGETVLRVESAVQPADAAVPSRAAARSEAGPQPV
RLALAALQSTRAEETGRHGGPRKVGTLRTVPETASAAGLAGRLQWKPASDGGLRAAISFTAEDAYGVRLGVLVRRLPESA
LLRVYRQDRPDAAYETRGSDVLQILARNAAAGDTSDAAKTWWTPDTGGSEATLEIDLPAGTSADALDIAIPSLVHIQEDL
SLSSSGDDALVTKNVGDAVACNLDSTCYDDYAQQRNAVARMVFVDSTGAHFCTGTLLNDRDGTRTPYFLTANHCIPSQTV
ASTLQTDWFFRSSSCNNRTLSPNAATRTGGAVLLYSGPDTDTAFLRLNDAPPPGAVFAAWDAGLQAMSAAVVGIHHPRGD
LQRISFGSIMGTLACSGDLESLTCDSATGDAANYYDVSLDRGTVEHGSSGSALFQGGRVIGTLYGYSGAGQCSPDGVRLY
ARFDHAYQAALKQWLSPATPARHRGHQPRVLPHHGHSGHGTPAAPQEAASVAQG

Specific function: Lysine-specific endoprotease. Involved in corneal virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003 [H]

Pfam domain/function: NA

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 55574; Mature: 55574

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQNMKNHRVSKWKIARRGGTLAGIAAALLIAGCGGGGGSTATASSSGETVLRVESAVQP
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCC
ADAAVPSRAAARSEAGPQPVRLALAALQSTRAEETGRHGGPRKVGTLRTVPETASAAGLA
CHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHCCCC
GRLQWKPASDGGLRAAISFTAEDAYGVRLGVLVRRLPESALLRVYRQDRPDAAYETRGSD
CEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHCCCHH
VLQILARNAAAGDTSDAAKTWWTPDTGGSEATLEIDLPAGTSADALDIAIPSLVHIQEDL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCHHHHHHHHC
SLSSSGDDALVTKNVGDAVACNLDSTCYDDYAQQRNAVARMVFVDSTGAHFCTGTLLNDR
CCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECC
DGTRTPYFLTANHCIPSQTVASTLQTDWFFRSSSCNNRTLSPNAATRTGGAVLLYSGPDT
CCCCCCEEEEECCCCCHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCCCEEEEEECCCC
DTAFLRLNDAPPPGAVFAAWDAGLQAMSAAVVGIHHPRGDLQRISFGSIMGTLACSGDLE
CEEEEEECCCCCCCCEEEEHHHHHHHHHHHEEEEECCCCCHHHEEHHHHHHHEEECCCCC
SLTCDSATGDAANYYDVSLDRGTVEHGSSGSALFQGGRVIGTLYGYSGAGQCSPDGVRLY
CEECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCCEEEE
ARFDHAYQAALKQWLSPATPARHRGHQPRVLPHHGHSGHGTPAAPQEAASVAQG
EEHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MNQNMKNHRVSKWKIARRGGTLAGIAAALLIAGCGGGGGSTATASSSGETVLRVESAVQP
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCC
ADAAVPSRAAARSEAGPQPVRLALAALQSTRAEETGRHGGPRKVGTLRTVPETASAAGLA
CHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHCCCC
GRLQWKPASDGGLRAAISFTAEDAYGVRLGVLVRRLPESALLRVYRQDRPDAAYETRGSD
CEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHCCCHH
VLQILARNAAAGDTSDAAKTWWTPDTGGSEATLEIDLPAGTSADALDIAIPSLVHIQEDL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCHHHHHHHHC
SLSSSGDDALVTKNVGDAVACNLDSTCYDDYAQQRNAVARMVFVDSTGAHFCTGTLLNDR
CCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECC
DGTRTPYFLTANHCIPSQTVASTLQTDWFFRSSSCNNRTLSPNAATRTGGAVLLYSGPDT
CCCCCCEEEEECCCCCHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCCCEEEEEECCCC
DTAFLRLNDAPPPGAVFAAWDAGLQAMSAAVVGIHHPRGDLQRISFGSIMGTLACSGDLE
CEEEEEECCCCCCCCEEEEHHHHHHHHHHHEEEEECCCCCHHHEEHHHHHHHEEECCCCC
SLTCDSATGDAANYYDVSLDRGTVEHGSSGSALFQGGRVIGTLYGYSGAGQCSPDGVRLY
CEECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCCEEEE
ARFDHAYQAALKQWLSPATPARHRGHQPRVLPHHGHSGHGTPAAPQEAASVAQG
EEHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12419815; 10984043 [H]