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The map label for this gene is yegE [C]

Identifier: 120612841

GI number: 120612841

Start: 4659835

End: 4661763

Strand: Reverse

Name: yegE [C]

Synonym: Aave_4205

Alternate gene names: 120612841

Gene position: 4661763-4659835 (Counterclockwise)

Preceding gene: 120612843

Following gene: 120612839

Centisome position: 87.09

GC content: 72.94

Gene sequence:

>1929_bases
ATGCCGCGCATCAATGCAATGCGGCGCCGGGCGGCCTGCGGCACAATCCGCCGCTGCCTTTTCCTTTCCAGTCCTCGCCC
GTGCCGCGGCCCCTGCGCCAGGCCATTGCGTCCCGTGCCGGTTTTTCCTTCCGCCCGCCTGCTGCTTTTGCGCACCGCCG
CGCGGTGCGGCGGCGCGCTGGCCGCCGCCCTGGCGTGGCTGTGCATGGTCCTCGTGGCGCCCGCCGCGCAGGCGGCAGCC
GTCGAGCCTGCGGGGCTCGCAGCGCGCGAGGGCGGAATTTCGCTCGTACCCCACATGGAGGTGCTGGAGGACCCCGGCCG
ACGCCTCGGGATCGGCGACATCCTCGCGCCGGAGAACGCGGCACGCTTCGCCCATCCCGACGATCCCCTGCGTGGCGCCG
AGGCCGACCGGGTGCTCTGGTTCCGCGTGCAGCTGCGCCTGGCCGATCCGGCGGACGCCCTGCGCGAATGGCTGCTGGTC
GTGCCCACGGTGTCCACCCACGATCTGCGCTTCTACGGGCCCTACGGCCCGGACGGCCGCGCGCTGGCGCCGCCCGTGGT
GACGGGCATGCGCCATCCGTGGGCCACGCGGCCGGCGGGATCGGAGCAGATGGCCTGGCGCTTCCGGCTGCCGGACGAGC
GGACGTACACGGCGTACTTCCGCGTGGAATCGACCTTCGCCCGTTTCTATGCCGCCAGGGCCTGGGATCTGGCCGACTAC
CTGCAGGCCACGCAGGACAAGCGCATGTTCGACGGTGCCTGCTATGGCCTGCTGCTGGGCCTGCTGGCCTTCAGCCTCGC
GATGCTGCTGGTGTTCCGCGAGGGCATCTATGCCTGGTATTCGCTCTCGTGCGCCTGTGCCCTGCTGGCGCTGGCCAGCC
TGAACGGGCACACGCTGCGCTATCCGTTCGCCCACTGGCCGGCGGCAGCGGGCCTCTTCTACACCCTGGCGCCGCCGCTT
TGGGCCATGTCCAAGCTGCTGTTCGGGCGCAGCCTGCTGCGCCTCTCGCACTACGCGCCGCGCATCGATCGCCTGGTGCT
CGCACTGGTCGCGGCGCTGGGCGCGGCGACCGTGTACGGGCTGTCCGGCCCCCATCCGCTCTGGCTGTTCCGGGCCGTGC
AGGCGTCGGTGATGGTGTCCACCGTGGTGCTGGCCGCCGGCGCGCTGATCGCGATGCGCAGGCGCTACTGGCCCGCCGTG
CTCTACAGCGCCGGCGTGCTGCTGCTGTTGCTGGGCATCTGCGCGATCATCGTCGCGAGCTGGGGCTGGGTGGCCTGGAC
GCCGGGCCAGATGGACCTGACACAGGCCGCGCTCGTGGCGGAAACCGTCATCTTCGCCGCCGCCATGGCGTCGCGGCTGC
GCATGCTCCGCATGTCCGAGCAGGCGCTCGGCCGGCGTACCCGCGAACTGGTGGAGGTGCTGGGCACGGACGCCCTCACG
GGCGCGGCGAACCGCGCCGGACTGGCGGGCCGTGCCGGGGCGGCCCTGGAGGCCGGCGAGCCGTTCACGCTCATGCTGCT
GGACCTGGACGGCTTCAAGGCCGTGAACGATACCTACGGCCATGCGGCGGGCGACGCCGTGCTGGTGGCCCTGGTGCAGC
GCCTGCGCGCCCTGCTGCGCGAAGGCGACCTGATCGCACGCCTGGGCGGCGACGAATTCGCCGTGCTCCTGGCCGGATCA
CCGCCGCGCACGGCCCTCGCGGACAAGGCCCGCGCCATGGCCCATGCCGTGGCCGTGCCCCTCGGCTTCGAAGGCCGGAA
CCTGTCGGTGGGCCTCAGCGTGGGCATCGCCAGCCATCCCGGCGACGGCCAGACCCTGGAATCCCTGCTGCGCGCCGCCG
ACGCCGCCATGTACGCCAGCAAGCGCCGCGGCCCGCAGGCCGGGGCGGAGTGCTTCGCCTTCGCGAGCGACTTGCCCCCG
GCGCCCTGA

Upstream 100 bases:

>100_bases
GAGCTGGAGCATGGGCAGCACTCGCAGGGGGTGAAAGGGAAGGCCGATGCTAGGGCCATGCGCCGCGCCTGCCAATGCCG
TATGTCCCGCCGATTGATAC

Downstream 100 bases:

>100_bases
CAGTCACTGCCTGGCCTTGCCTTCGGTGCGTTGGCATGGAGATGGCTCCGTGCGACGGTTGCCTGGCGTGCGGCCCTGGA
ACCCGCACTGCACGGAGGCG

Product: sensor diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MPRINAMRRRAACGTIRRCLFLSSPRPCRGPCARPLRPVPVFPSARLLLLRTAARCGGALAAALAWLCMVLVAPAAQAAA
VEPAGLAAREGGISLVPHMEVLEDPGRRLGIGDILAPENAARFAHPDDPLRGAEADRVLWFRVQLRLADPADALREWLLV
VPTVSTHDLRFYGPYGPDGRALAPPVVTGMRHPWATRPAGSEQMAWRFRLPDERTYTAYFRVESTFARFYAARAWDLADY
LQATQDKRMFDGACYGLLLGLLAFSLAMLLVFREGIYAWYSLSCACALLALASLNGHTLRYPFAHWPAAAGLFYTLAPPL
WAMSKLLFGRSLLRLSHYAPRIDRLVLALVAALGAATVYGLSGPHPLWLFRAVQASVMVSTVVLAAGALIAMRRRYWPAV
LYSAGVLLLLLGICAIIVASWGWVAWTPGQMDLTQAALVAETVIFAAAMASRLRMLRMSEQALGRRTRELVEVLGTDALT
GAANRAGLAGRAGAALEAGEPFTLMLLDLDGFKAVNDTYGHAAGDAVLVALVQRLRALLREGDLIARLGGDEFAVLLAGS
PPRTALADKARAMAHAVAVPLGFEGRNLSVGLSVGIASHPGDGQTLESLLRAADAAMYASKRRGPQAGAECFAFASDLPP
AP

Sequences:

>Translated_642_residues
MPRINAMRRRAACGTIRRCLFLSSPRPCRGPCARPLRPVPVFPSARLLLLRTAARCGGALAAALAWLCMVLVAPAAQAAA
VEPAGLAAREGGISLVPHMEVLEDPGRRLGIGDILAPENAARFAHPDDPLRGAEADRVLWFRVQLRLADPADALREWLLV
VPTVSTHDLRFYGPYGPDGRALAPPVVTGMRHPWATRPAGSEQMAWRFRLPDERTYTAYFRVESTFARFYAARAWDLADY
LQATQDKRMFDGACYGLLLGLLAFSLAMLLVFREGIYAWYSLSCACALLALASLNGHTLRYPFAHWPAAAGLFYTLAPPL
WAMSKLLFGRSLLRLSHYAPRIDRLVLALVAALGAATVYGLSGPHPLWLFRAVQASVMVSTVVLAAGALIAMRRRYWPAV
LYSAGVLLLLLGICAIIVASWGWVAWTPGQMDLTQAALVAETVIFAAAMASRLRMLRMSEQALGRRTRELVEVLGTDALT
GAANRAGLAGRAGAALEAGEPFTLMLLDLDGFKAVNDTYGHAAGDAVLVALVQRLRALLREGDLIARLGGDEFAVLLAGS
PPRTALADKARAMAHAVAVPLGFEGRNLSVGLSVGIASHPGDGQTLESLLRAADAAMYASKRRGPQAGAECFAFASDLPP
AP
>Mature_641_residues
PRINAMRRRAACGTIRRCLFLSSPRPCRGPCARPLRPVPVFPSARLLLLRTAARCGGALAAALAWLCMVLVAPAAQAAAV
EPAGLAAREGGISLVPHMEVLEDPGRRLGIGDILAPENAARFAHPDDPLRGAEADRVLWFRVQLRLADPADALREWLLVV
PTVSTHDLRFYGPYGPDGRALAPPVVTGMRHPWATRPAGSEQMAWRFRLPDERTYTAYFRVESTFARFYAARAWDLADYL
QATQDKRMFDGACYGLLLGLLAFSLAMLLVFREGIYAWYSLSCACALLALASLNGHTLRYPFAHWPAAAGLFYTLAPPLW
AMSKLLFGRSLLRLSHYAPRIDRLVLALVAALGAATVYGLSGPHPLWLFRAVQASVMVSTVVLAAGALIAMRRRYWPAVL
YSAGVLLLLLGICAIIVASWGWVAWTPGQMDLTQAALVAETVIFAAAMASRLRMLRMSEQALGRRTRELVEVLGTDALTG
AANRAGLAGRAGAALEAGEPFTLMLLDLDGFKAVNDTYGHAAGDAVLVALVQRLRALLREGDLIARLGGDEFAVLLAGSP
PRTALADKARAMAHAVAVPLGFEGRNLSVGLSVGIASHPGDGQTLESLLRAADAAMYASKRRGPQAGAECFAFASDLPPA
P

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=164, Percent_Identity=37.1951219512195, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=33.8983050847458, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=32.7485380116959, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787802, Length=264, Percent_Identity=27.6515151515151, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787541, Length=163, Percent_Identity=34.3558282208589, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081974, Length=181, Percent_Identity=29.2817679558011, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081977, Length=184, Percent_Identity=30.9782608695652, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=31.6455696202532, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788956, Length=193, Percent_Identity=32.6424870466321, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787056, Length=149, Percent_Identity=33.5570469798658, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787816, Length=156, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=155, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=31.547619047619, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 68923; Mature: 68792

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRINAMRRRAACGTIRRCLFLSSPRPCRGPCARPLRPVPVFPSARLLLLRTAARCGGAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHH
AAALAWLCMVLVAPAAQAAAVEPAGLAAREGGISLVPHMEVLEDPGRRLGIGDILAPENA
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEECCCHHHHHCCCCEECCCCCCCCCCC
ARFAHPDDPLRGAEADRVLWFRVQLRLADPADALREWLLVVPTVSTHDLRFYGPYGPDGR
CCCCCCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHEEECCCCCCCEEEECCCCCCCC
ALAPPVVTGMRHPWATRPAGSEQMAWRFRLPDERTYTAYFRVESTFARFYAARAWDLADY
CCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHH
LQATQDKRMFDGACYGLLLGLLAFSLAMLLVFREGIYAWYSLSCACALLALASLNGHTLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YPFAHWPAAAGLFYTLAPPLWAMSKLLFGRSLLRLSHYAPRIDRLVLALVAALGAATVYG
CCCHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEC
LSGPHPLWLFRAVQASVMVSTVVLAAGALIAMRRRYWPAVLYSAGVLLLLLGICAIIVAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WGWVAWTPGQMDLTQAALVAETVIFAAAMASRLRMLRMSEQALGRRTRELVEVLGTDALT
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
GAANRAGLAGRAGAALEAGEPFTLMLLDLDGFKAVNDTYGHAAGDAVLVALVQRLRALLR
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
EGDLIARLGGDEFAVLLAGSPPRTALADKARAMAHAVAVPLGFEGRNLSVGLSVGIASHP
CCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCC
GDGQTLESLLRAADAAMYASKRRGPQAGAECFAFASDLPPAP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRINAMRRRAACGTIRRCLFLSSPRPCRGPCARPLRPVPVFPSARLLLLRTAARCGGAL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHH
AAALAWLCMVLVAPAAQAAAVEPAGLAAREGGISLVPHMEVLEDPGRRLGIGDILAPENA
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEECCCHHHHHCCCCEECCCCCCCCCCC
ARFAHPDDPLRGAEADRVLWFRVQLRLADPADALREWLLVVPTVSTHDLRFYGPYGPDGR
CCCCCCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHEEECCCCCCCEEEECCCCCCCC
ALAPPVVTGMRHPWATRPAGSEQMAWRFRLPDERTYTAYFRVESTFARFYAARAWDLADY
CCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHH
LQATQDKRMFDGACYGLLLGLLAFSLAMLLVFREGIYAWYSLSCACALLALASLNGHTLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YPFAHWPAAAGLFYTLAPPLWAMSKLLFGRSLLRLSHYAPRIDRLVLALVAALGAATVYG
CCCHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEC
LSGPHPLWLFRAVQASVMVSTVVLAAGALIAMRRRYWPAVLYSAGVLLLLLGICAIIVAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WGWVAWTPGQMDLTQAALVAETVIFAAAMASRLRMLRMSEQALGRRTRELVEVLGTDALT
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
GAANRAGLAGRAGAALEAGEPFTLMLLDLDGFKAVNDTYGHAAGDAVLVALVQRLRALLR
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
EGDLIARLGGDEFAVLLAGSPPRTALADKARAMAHAVAVPLGFEGRNLSVGLSVGIASHP
CCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCC
GDGQTLESLLRAADAAMYASKRRGPQAGAECFAFASDLPPAP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]