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The map label for this gene is tagO [H]

Identifier: 120612777

GI number: 120612777

Start: 4590122

End: 4591225

Strand: Reverse

Name: tagO [H]

Synonym: Aave_4140

Alternate gene names: 120612777

Gene position: 4591225-4590122 (Counterclockwise)

Preceding gene: 120612778

Following gene: 120612776

Centisome position: 85.77

GC content: 67.21

Gene sequence:

>1104_bases
ATGATCTGGTTGTCTCTGGTCAGTTTCCTGGCAACGGCCCTCGCTGCTGCATGCATCGTCCGTTGGGGGCGAGGCCATGC
CGCGAACTACGGCGATGCCATGCCGCAGCGTTTCCACCTGGGGGATGTGCCCCGCCTGGGCGGGGCGGCGTTGCTGGCCG
GCATGGTCCTCAGCTGGGCGCTGGGCGCGCTCCAGTCGATCCTGTGGGGCGATCCGGGATCCTTGCGGCTGGGCATCTGG
GTCGGCTGGTGGATGGCCTGCCTGCTGCCGGCGGCCATCGGCGGCATGGCGGAGGACGTGACGCAGCGCCTGCCCGTTCG
CTACAGGCTGCTGCTCACGGCGATGTCCGGCGGGATCGCGCTGATGGTGCTCAACATGAACGTGCCCCGGCTGGGGCTGC
CCTGGCTGGACGCGCATCTGGTGGAGATGCCCTGGCTGGGCATGTGCATCGTGGTCCTGGCAGTCGCGGGCCTGCCGCAC
GCCTTCAACATCATCGACGGCTACAACGGGCTGGCCGGCATGGTGGCGCTCATCGTCTGCCTTGCGCTGGCGCATGTGAG
CCTGCAGGTGGGCGACCGTGCCCTGGCTTCCCTGCTGATCTGCACCGCGGCGGCCACCGTCGGCTTCCTCGTCTGGAATT
ATCCGCGGGGCATGCTGTTCGCGGGCGACAGCGGCGCCTACATCTGGGGAGTGATGATCGCGCTCAGCAGCATCGCGCTG
GTCCAGCGCAACCGCGACGTGTCCCCCTGGTTTCCCATGCTGCTGCTGATGTACCCCGTGTGGGAGACGGTGTTTTCCAG
CTACCGCAAGCTCGCGCGGGGCGTTTCGCCGGGAGTGGCCGATGCCCTTCATTTCCACCAGCTCATCTACCGGCGCATCG
TGCGCGGGGTGTTCCACGACGACGAGTCGCGGCGGGTGCTCATGCGCAACAACCGCACGTCCCCCTATCTCTGGGGCTTC
ACGATGCTCACCGTGGTGCCGGCCGTGCTGTTCTGGAGCAATACGCCGGTGCTGATGGTGTTCTGCGGCCTGTTCGGCCT
GACCTACGTGACGGCCTACCTGGCCATCGTGCGGTTCAAGGTCCCCATCTGGCTGAGGCACTGA

Upstream 100 bases:

>100_bases
ATGTCCGGAGCCTGTTGAGGCTATGGACGTCACCTGTGTATCACCAGGCGCGACCTTTGTTGCGGGCGGATACCGCTCAA
GCGCGTAGGATCGGCGCCCC

Downstream 100 bases:

>100_bases
AGCGGCCTGCGCCGGGGCGTGGCCTCCCGGCGCGCCGCAAGGCGCGGCAGAGCGGGCACAATGCGCACTTCTTCACTGAC
TGCCGCCCTGTTTTTTCCAC

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MIWLSLVSFLATALAAACIVRWGRGHAANYGDAMPQRFHLGDVPRLGGAALLAGMVLSWALGALQSILWGDPGSLRLGIW
VGWWMACLLPAAIGGMAEDVTQRLPVRYRLLLTAMSGGIALMVLNMNVPRLGLPWLDAHLVEMPWLGMCIVVLAVAGLPH
AFNIIDGYNGLAGMVALIVCLALAHVSLQVGDRALASLLICTAAATVGFLVWNYPRGMLFAGDSGAYIWGVMIALSSIAL
VQRNRDVSPWFPMLLLMYPVWETVFSSYRKLARGVSPGVADALHFHQLIYRRIVRGVFHDDESRRVLMRNNRTSPYLWGF
TMLTVVPAVLFWSNTPVLMVFCGLFGLTYVTAYLAIVRFKVPIWLRH

Sequences:

>Translated_367_residues
MIWLSLVSFLATALAAACIVRWGRGHAANYGDAMPQRFHLGDVPRLGGAALLAGMVLSWALGALQSILWGDPGSLRLGIW
VGWWMACLLPAAIGGMAEDVTQRLPVRYRLLLTAMSGGIALMVLNMNVPRLGLPWLDAHLVEMPWLGMCIVVLAVAGLPH
AFNIIDGYNGLAGMVALIVCLALAHVSLQVGDRALASLLICTAAATVGFLVWNYPRGMLFAGDSGAYIWGVMIALSSIAL
VQRNRDVSPWFPMLLLMYPVWETVFSSYRKLARGVSPGVADALHFHQLIYRRIVRGVFHDDESRRVLMRNNRTSPYLWGF
TMLTVVPAVLFWSNTPVLMVFCGLFGLTYVTAYLAIVRFKVPIWLRH
>Mature_367_residues
MIWLSLVSFLATALAAACIVRWGRGHAANYGDAMPQRFHLGDVPRLGGAALLAGMVLSWALGALQSILWGDPGSLRLGIW
VGWWMACLLPAAIGGMAEDVTQRLPVRYRLLLTAMSGGIALMVLNMNVPRLGLPWLDAHLVEMPWLGMCIVVLAVAGLPH
AFNIIDGYNGLAGMVALIVCLALAHVSLQVGDRALASLLICTAAATVGFLVWNYPRGMLFAGDSGAYIWGVMIALSSIAL
VQRNRDVSPWFPMLLLMYPVWETVFSSYRKLARGVSPGVADALHFHQLIYRRIVRGVFHDDESRRVLMRNNRTSPYLWGF
TMLTVVPAVLFWSNTPVLMVFCGLFGLTYVTAYLAIVRFKVPIWLRH

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 40376; Mature: 40376

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWLSLVSFLATALAAACIVRWGRGHAANYGDAMPQRFHLGDVPRLGGAALLAGMVLSWA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGALQSILWGDPGSLRLGIWVGWWMACLLPAAIGGMAEDVTQRLPVRYRLLLTAMSGGIA
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCEE
LMVLNMNVPRLGLPWLDAHLVEMPWLGMCIVVLAVAGLPHAFNIIDGYNGLAGMVALIVC
EEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHH
LALAHVSLQVGDRALASLLICTAAATVGFLVWNYPRGMLFAGDSGAYIWGVMIALSSIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHH
VQRNRDVSPWFPMLLLMYPVWETVFSSYRKLARGVSPGVADALHFHQLIYRRIVRGVFHD
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DESRRVLMRNNRTSPYLWGFTMLTVVPAVLFWSNTPVLMVFCGLFGLTYVTAYLAIVRFK
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VPIWLRH
CCEEECC
>Mature Secondary Structure
MIWLSLVSFLATALAAACIVRWGRGHAANYGDAMPQRFHLGDVPRLGGAALLAGMVLSWA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGALQSILWGDPGSLRLGIWVGWWMACLLPAAIGGMAEDVTQRLPVRYRLLLTAMSGGIA
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCEE
LMVLNMNVPRLGLPWLDAHLVEMPWLGMCIVVLAVAGLPHAFNIIDGYNGLAGMVALIVC
EEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHH
LALAHVSLQVGDRALASLLICTAAATVGFLVWNYPRGMLFAGDSGAYIWGVMIALSSIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHH
VQRNRDVSPWFPMLLLMYPVWETVFSSYRKLARGVSPGVADALHFHQLIYRRIVRGVFHD
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DESRRVLMRNNRTSPYLWGFTMLTVVPAVLFWSNTPVLMVFCGLFGLTYVTAYLAIVRFK
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VPIWLRH
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]